Sentences with phrase «system pathways for»

But they do share many of the same nervous system pathways for relaying signals.

Not exact matches

«Partnerships like this one have reinvigorated our nation's apprenticeship system, creating opportunity and pathways to prosperity for hundreds of thousands of Americans that will last for years to come.»
Our immigration system can strategically recruit top talent; we could market short pathways to citizenship for top Indian graduates, and for those working for listed companies or studying in leading U.S. graduate programs.
The same pathway that has put many in the seat of a new car — the lease — is taking off as a financial vehicle for homeowners who don't have tens of thousands of dollars sitting around to buy a rooftop solar - panel system outright.
In many animal model systems, for example, the precise genes involved in sexual partner selection have been identified, and their neuro - biochemical pathways have been worked out in great detail.
British Cycling has begun work on talent mapping — a «talent pathway» system for identifying talent and providing structured career progression to its staff (On - going).
In our current high stakes system where every test or assignment seems to be a critical step on the pathway to adult success, students frequently feel that they have no room for error.
A new pathway system, upgrading of turf and new tree plantings could also be paid for with the grant money, Gordon said.
One of the largest university systems in the country, CUNY sees itself as one of the only affordable pathways to opportunity for the city's underprivileged.
A bipartisan group of senators has agreed on a set of principles for a sweeping overhaul of the immigration system, including a pathway to American citizenship for 11 million illegal immigrants.
«For us, it's very important to understand the neural circuits or pathways so that we can develop therapies specifically for pain or itch, instead of targeting it as a whole system,» says Santosh Mishra, assistant professor of neuroscience in NC State's College of Veterinary Medicine and the corresponding author of a paper on the topFor us, it's very important to understand the neural circuits or pathways so that we can develop therapies specifically for pain or itch, instead of targeting it as a whole system,» says Santosh Mishra, assistant professor of neuroscience in NC State's College of Veterinary Medicine and the corresponding author of a paper on the topfor pain or itch, instead of targeting it as a whole system,» says Santosh Mishra, assistant professor of neuroscience in NC State's College of Veterinary Medicine and the corresponding author of a paper on the topic.
This one recommendation, which came at the end of the day, seemed to meet with the approval of all present — the need for a comprehensive information system capable of more accurately tracking and modeling the S&E education and workforce pathways.
The agency supports network science through individual institutes (for example, the National Institute of General Medical Sciences funds nine National Centers for Systems Biology, academic centers that emphasize network biology) and through agencywide initiatives (such as the National Technology Centers for Networks and Pathways, funded by the NIH Roadmap for Medical Research and the recently announced Human Connectome Project, which aims to map the connections among the human brain's 100 billion neurons).
«This research adds further significance to the role of p75 as a master regulator for many different signaling pathways that are vital for the nervous system to function normally.»
IL - 17 is in a signaling pathway that acts as a feedback loop for the immune system.
A new study in American Journal of Physiology — Heart and Circulatory Physiology identifies the involvement of a protective response pathway, the heme oxygenase system, that has potential as a new therapeutic strategy for cardiovascular diseases.
«We have achieved the important goal of helping these young patients and made progress in understanding the biological pathways and proteins that are important for the regulation of the immune system's responses.»
Male offspring showed stronger motivation to self - administer heroin during their adulthood and molecular changes in the glutamatergic system, which is the most important excitatory pathway for neurotransmission in the brain.
Dr. Sharma is a trained medical oncologist and immunologist whose research work is focused on investigating mechanisms and pathways within the immune system that are responsible for tumor rejection and clinical benefit.
This helped to confirm that in addition to relying on leaky blood vessels for nanoparticles to gain access to the tumor, a major inducible vascular transit pathway is available in the form of the vesicle transport system.
The Hippo signaling pathway, which is highly conserved up to humans, was known to play a critical role in organ size determination, like, for example, in the liver, but has not been demonstrated to influence neural stem cells in the central nervous system.
«Not only does this report shed light on how colds exacerbate asthma, it also suggests new pathways and existing drugs that might be exploited to limit this, in some cases, severe combination of respiratory events,» said John Wherry, Ph.D., Deputy Editor of the Journal of Leukocyte Biology, «These findings also highlight an emerging appreciation for the interaction between metabolic pathways and the immune system
Advances in high - temperature components and improved system modeling, combined with the potential for conversion costs an order of magnitude lower than those of turbines, suggest that TPV could offer a pathway for efficiently storing and producing electrical power from solar thermal sources, a new study suggests.
Janus kinases carry out important intracellular functions in many organs — for instance, activating key signal pathways in the systems which form new blood cells.
For example, we used to think that ring contraction to give the corrin system occurred quite late in the pathway.
Interestingly, these changes are related to the so - called PINK1 - Parkin pathway that is responsible for the mitochondrial quality control system and implicated in Parkinson's disease.
According to U of I researcher Cory Suski, although the extensive canal system protects the Lake Michigan water supply, it created another problem — numerous entry points and pathways for invasive Asian carp.
Recently, the Center for Lighting Enabled Systems & Applications (LESA) at Rensselaer Polytechnic Institute, together with the Illumination Engineering Society (IES), sponsored a workshop to explore pathways to define and promote the adoption of lighting systems specifically for health - care enviroSystems & Applications (LESA) at Rensselaer Polytechnic Institute, together with the Illumination Engineering Society (IES), sponsored a workshop to explore pathways to define and promote the adoption of lighting systems specifically for health - care envirosystems specifically for health - care environments.
Pathway information for systems biology Cary MP, Bader GD, Sander C FEBS Lett.
Hopefully, this knowledge, coupled to utility of the mAGES system, will spark the search for small molecule drug combinations which can safely and efficiently modulate the involved pathways and promote astrocyte to NSC conversion.
The Application of Omics Data to the Development of AOPs — Mary T. McBride, A Systems Biology Approach to Advancing Adverse Outcome Pathways for Risk Assessment
If I have part of an oncogenic pathway with two genes (A and B), then we expect that mutations in either one may be enough to disrupt the system, and there will be no selective pressure for mutation in the other.
Using the liquid SIMS technique and the newly patented electrochemical System for Analysis at the Liquid Vacuum Interface (SALVI), the researchers discovered transient species and reaction pathways in the solid - liquid interface.
Dr. Levitsky: My organization within Roche, Pharma Research and Early Development (pRED), has invested in antibody engineering, not only for use of monoclonal antibodies in the established ways of delivering cell - killing agents to tumors or interrupting cell signalling pathways, but also as ways to engage and manipulate the immune system's response to tumors.
I have a graduate degree in Systems Science and a passion for the kind of problem solving that can come out of interdisciplinary research, and I've come to see this as a natural pathway into RD work.
Through systematic annotation of the resulting movies, we developed a phenotypic profiling system, which shows high correlation with cellular processes and biochemical pathways, thus enabling us to predict new functions for previously uncharacterized genes.
The Th17 - ELR + CXC chemokine pathway is essential for the development of central nervous system autoimmune disease.
8.30 Hana Paculová CDK12 connects transcriptional regulation to DNA damage repair pathway 8.55 Karol Kaiser Wnt secretion during nervous system development 9.20 Simona Hankeová The role of Notch signaling in vasculogenesis 10.00 Coffee break 10.30 Tomáš Doležal Extracellular adenosine regulates complex host - pathogen interactions through the energy release for the immune response 10.55 Ondřej Bernatík and Igor Červenka Regulation of diverse function of Dvl by phosphorylation 11.20 Jan Ryneš Dissection of Axin interactome: rational approach for control of signaling cascades via intervention with specific protein - protein interactions 12.05 Targeting opportunities: discussion & sum - up 13.00 Lunch and departure
Previous work has given insights into the mechanistic pathways leading to small molecule sequestration in membrane - free coacervate protocells; successfully demonstrated the use of liquid - liquid phase separated micro compartments for protein expression using cell free expression systems; exploited microfluidics for the high throughput formation of stable, monodisperse microdroplets; and integrated two contrasting modes of protocell construction to produce a novel hybrid model based on fatty acid membrane - bound coacervate micro-droplets.
The embryonic Drosophila central nervous system similar to the human spinal cord is a paradigm for understanding the cellular processes and genetic pathways regulating the formation and maintenance of a diverse population of nerve cells.
Why it matters: Parkinson's disease is marked by the loss of dopamine in the brain's nigrostriatal neural pathway, which is one of four major pathways for this hormone and neurotransmitter in the brain; the disease primarily affects part of the motor system involved in the production and coordination of movement.
Biomarkers (Rick Paules, Section Editor): This section will present a forum for innovative scientific studies that integrate genomic, proteomic and metabolomic approaches with studies of complex physiological regulatory processes to gain a systems biology insight into complex pathways and networks controlling homeostatic and pathophysiologic states.
Our goal is to provide intuitive bioinformatics tools for the visualization, interpretation and analysis of pathway knowledge to support basic research, genome analysis, modeling, systems biology and education.
They linked these behaviors to immune pathways, implicating that targeting key components of the immune system could be a new therapeutic strategy for FTD.
These less acknowledged mechanisms of interaction and molecular control might have made the initial pathways to prebiotic systems evolution more intricate, but were surely essential for sustaining far - from - equilibrium chemical dynamics, given their functional relevance in all modern cells.
The anterograde (forward) tracing results of retinal projections in the garden warbler demonstrated virtually identical connections between the eye and the brain as known from other lateral - eyed bird species [e.g. 15]--[18]: fibers either projected onto the contralateral optic tectum (part of the tectofugal system), to the nucleus of the basal optic root (part of the accessory pathway)(data not shown) or curved into the thalamus innervating the dorsal geniculate complex (Gld, for details, see Fig. 1C, 2A, D).
Systems biology is the study of the interactions between the components of a biological system, and how these interactions give rise to the function and behavior of that system (for example, the enzymes and metabolites in a metabolic pathway).
«Right now we have some advanced tools we can use to stimulate the nervous system — very specific pathways in the brain and spinal cord,» said Horner, who is also vice chairman of research for the Department of Neurosurgery at Houston Methodist.
The endocannabinoid system regulates energy homeostasis through G protein — coupled cannabinoid - 1 receptors5, 6 located in the central nervous system and in various peripheral tissues, including adipose tissue, muscle, the gastrointestinal tract, and the liver.7 While peripheral cannabinoid - 1 receptor activation decreases adiponectin production in adipocytes, 8 central cannabinoid - 1 receptor activation in preclinical studies stimulates eating, decreases muscle, and stimulates hepatic and adipose tissue lipogenic pathways in animal models of obesity.9 In genetic and diet - induced obesity, rimonabant, a selective cannabinoid - 1 receptor blocker, reduces overactivation of the central8, 10 and peripheral11, 12 endocannabinoid system8, 10,13 and prevents weight gain and associated metabolic disorders, thus revealing a novel strategy for the treatment of obesity and related cardiometabolic disorders.
Finally, the strategy applied here for selective delivery of MK801 can be extended to other small molecules for use in brain tissue (Tian et al., 2012), allowing for an approach that combines chemistry, molecular genetics, and neurobiology to dissect cell signaling pathways in specific cell types in the central nervous system.
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