But they do share many of the same nervous
system pathways for relaying signals.
Not exact matches
«Partnerships like this one have reinvigorated our nation's apprenticeship
system, creating opportunity and
pathways to prosperity
for hundreds of thousands of Americans that will last
for years to come.»
Our immigration
system can strategically recruit top talent; we could market short
pathways to citizenship
for top Indian graduates, and
for those working
for listed companies or studying in leading U.S. graduate programs.
The same
pathway that has put many in the seat of a new car — the lease — is taking off as a financial vehicle
for homeowners who don't have tens of thousands of dollars sitting around to buy a rooftop solar - panel
system outright.
In many animal model
systems,
for example, the precise genes involved in sexual partner selection have been identified, and their neuro - biochemical
pathways have been worked out in great detail.
British Cycling has begun work on talent mapping — a «talent
pathway»
system for identifying talent and providing structured career progression to its staff (On - going).
In our current high stakes
system where every test or assignment seems to be a critical step on the
pathway to adult success, students frequently feel that they have no room
for error.
A new
pathway system, upgrading of turf and new tree plantings could also be paid
for with the grant money, Gordon said.
One of the largest university
systems in the country, CUNY sees itself as one of the only affordable
pathways to opportunity
for the city's underprivileged.
A bipartisan group of senators has agreed on a set of principles
for a sweeping overhaul of the immigration
system, including a
pathway to American citizenship
for 11 million illegal immigrants.
«
For us, it's very important to understand the neural circuits or pathways so that we can develop therapies specifically for pain or itch, instead of targeting it as a whole system,» says Santosh Mishra, assistant professor of neuroscience in NC State's College of Veterinary Medicine and the corresponding author of a paper on the top
For us, it's very important to understand the neural circuits or
pathways so that we can develop therapies specifically
for pain or itch, instead of targeting it as a whole system,» says Santosh Mishra, assistant professor of neuroscience in NC State's College of Veterinary Medicine and the corresponding author of a paper on the top
for pain or itch, instead of targeting it as a whole
system,» says Santosh Mishra, assistant professor of neuroscience in NC State's College of Veterinary Medicine and the corresponding author of a paper on the topic.
This one recommendation, which came at the end of the day, seemed to meet with the approval of all present — the need
for a comprehensive information
system capable of more accurately tracking and modeling the S&E education and workforce
pathways.
The agency supports network science through individual institutes (
for example, the National Institute of General Medical Sciences funds nine National Centers
for Systems Biology, academic centers that emphasize network biology) and through agencywide initiatives (such as the National Technology Centers
for Networks and
Pathways, funded by the NIH Roadmap
for Medical Research and the recently announced Human Connectome Project, which aims to map the connections among the human brain's 100 billion neurons).
«This research adds further significance to the role of p75 as a master regulator
for many different signaling
pathways that are vital
for the nervous
system to function normally.»
IL - 17 is in a signaling
pathway that acts as a feedback loop
for the immune
system.
A new study in American Journal of Physiology — Heart and Circulatory Physiology identifies the involvement of a protective response
pathway, the heme oxygenase
system, that has potential as a new therapeutic strategy
for cardiovascular diseases.
«We have achieved the important goal of helping these young patients and made progress in understanding the biological
pathways and proteins that are important
for the regulation of the immune
system's responses.»
Male offspring showed stronger motivation to self - administer heroin during their adulthood and molecular changes in the glutamatergic
system, which is the most important excitatory
pathway for neurotransmission in the brain.
Dr. Sharma is a trained medical oncologist and immunologist whose research work is focused on investigating mechanisms and
pathways within the immune
system that are responsible
for tumor rejection and clinical benefit.
This helped to confirm that in addition to relying on leaky blood vessels
for nanoparticles to gain access to the tumor, a major inducible vascular transit
pathway is available in the form of the vesicle transport
system.
The Hippo signaling
pathway, which is highly conserved up to humans, was known to play a critical role in organ size determination, like,
for example, in the liver, but has not been demonstrated to influence neural stem cells in the central nervous
system.
«Not only does this report shed light on how colds exacerbate asthma, it also suggests new
pathways and existing drugs that might be exploited to limit this, in some cases, severe combination of respiratory events,» said John Wherry, Ph.D., Deputy Editor of the Journal of Leukocyte Biology, «These findings also highlight an emerging appreciation
for the interaction between metabolic
pathways and the immune
system.»
Advances in high - temperature components and improved
system modeling, combined with the potential
for conversion costs an order of magnitude lower than those of turbines, suggest that TPV could offer a
pathway for efficiently storing and producing electrical power from solar thermal sources, a new study suggests.
Janus kinases carry out important intracellular functions in many organs —
for instance, activating key signal
pathways in the
systems which form new blood cells.
For example, we used to think that ring contraction to give the corrin
system occurred quite late in the
pathway.
Interestingly, these changes are related to the so - called PINK1 - Parkin
pathway that is responsible
for the mitochondrial quality control
system and implicated in Parkinson's disease.
According to U of I researcher Cory Suski, although the extensive canal
system protects the Lake Michigan water supply, it created another problem — numerous entry points and
pathways for invasive Asian carp.
Recently, the Center
for Lighting Enabled
Systems & Applications (LESA) at Rensselaer Polytechnic Institute, together with the Illumination Engineering Society (IES), sponsored a workshop to explore pathways to define and promote the adoption of lighting systems specifically for health - care enviro
Systems & Applications (LESA) at Rensselaer Polytechnic Institute, together with the Illumination Engineering Society (IES), sponsored a workshop to explore
pathways to define and promote the adoption of lighting
systems specifically for health - care enviro
systems specifically
for health - care environments.
Pathway information
for systems biology Cary MP, Bader GD, Sander C FEBS Lett.
Hopefully, this knowledge, coupled to utility of the mAGES
system, will spark the search
for small molecule drug combinations which can safely and efficiently modulate the involved
pathways and promote astrocyte to NSC conversion.
The Application of Omics Data to the Development of AOPs — Mary T. McBride, A
Systems Biology Approach to Advancing Adverse Outcome
Pathways for Risk Assessment
If I have part of an oncogenic
pathway with two genes (A and B), then we expect that mutations in either one may be enough to disrupt the
system, and there will be no selective pressure
for mutation in the other.
Using the liquid SIMS technique and the newly patented electrochemical
System for Analysis at the Liquid Vacuum Interface (SALVI), the researchers discovered transient species and reaction
pathways in the solid - liquid interface.
Dr. Levitsky: My organization within Roche, Pharma Research and Early Development (pRED), has invested in antibody engineering, not only
for use of monoclonal antibodies in the established ways of delivering cell - killing agents to tumors or interrupting cell signalling
pathways, but also as ways to engage and manipulate the immune
system's response to tumors.
I have a graduate degree in
Systems Science and a passion
for the kind of problem solving that can come out of interdisciplinary research, and I've come to see this as a natural
pathway into RD work.
Through systematic annotation of the resulting movies, we developed a phenotypic profiling
system, which shows high correlation with cellular processes and biochemical
pathways, thus enabling us to predict new functions
for previously uncharacterized genes.
The Th17 - ELR + CXC chemokine
pathway is essential
for the development of central nervous
system autoimmune disease.
8.30 Hana Paculová CDK12 connects transcriptional regulation to DNA damage repair
pathway 8.55 Karol Kaiser Wnt secretion during nervous
system development 9.20 Simona Hankeová The role of Notch signaling in vasculogenesis 10.00 Coffee break 10.30 Tomáš Doležal Extracellular adenosine regulates complex host - pathogen interactions through the energy release
for the immune response 10.55 Ondřej Bernatík and Igor Červenka Regulation of diverse function of Dvl by phosphorylation 11.20 Jan Ryneš Dissection of Axin interactome: rational approach
for control of signaling cascades via intervention with specific protein - protein interactions 12.05 Targeting opportunities: discussion & sum - up 13.00 Lunch and departure
Previous work has given insights into the mechanistic
pathways leading to small molecule sequestration in membrane - free coacervate protocells; successfully demonstrated the use of liquid - liquid phase separated micro compartments
for protein expression using cell free expression
systems; exploited microfluidics
for the high throughput formation of stable, monodisperse microdroplets; and integrated two contrasting modes of protocell construction to produce a novel hybrid model based on fatty acid membrane - bound coacervate micro-droplets.
The embryonic Drosophila central nervous
system similar to the human spinal cord is a paradigm
for understanding the cellular processes and genetic
pathways regulating the formation and maintenance of a diverse population of nerve cells.
Why it matters: Parkinson's disease is marked by the loss of dopamine in the brain's nigrostriatal neural
pathway, which is one of four major
pathways for this hormone and neurotransmitter in the brain; the disease primarily affects part of the motor
system involved in the production and coordination of movement.
Biomarkers (Rick Paules, Section Editor): This section will present a forum
for innovative scientific studies that integrate genomic, proteomic and metabolomic approaches with studies of complex physiological regulatory processes to gain a
systems biology insight into complex
pathways and networks controlling homeostatic and pathophysiologic states.
Our goal is to provide intuitive bioinformatics tools
for the visualization, interpretation and analysis of
pathway knowledge to support basic research, genome analysis, modeling,
systems biology and education.
They linked these behaviors to immune
pathways, implicating that targeting key components of the immune
system could be a new therapeutic strategy
for FTD.
These less acknowledged mechanisms of interaction and molecular control might have made the initial
pathways to prebiotic
systems evolution more intricate, but were surely essential
for sustaining far - from - equilibrium chemical dynamics, given their functional relevance in all modern cells.
The anterograde (forward) tracing results of retinal projections in the garden warbler demonstrated virtually identical connections between the eye and the brain as known from other lateral - eyed bird species [e.g. 15]--[18]: fibers either projected onto the contralateral optic tectum (part of the tectofugal
system), to the nucleus of the basal optic root (part of the accessory
pathway)(data not shown) or curved into the thalamus innervating the dorsal geniculate complex (Gld,
for details, see Fig. 1C, 2A, D).
Systems biology is the study of the interactions between the components of a biological
system, and how these interactions give rise to the function and behavior of that
system (
for example, the enzymes and metabolites in a metabolic
pathway).
«Right now we have some advanced tools we can use to stimulate the nervous
system — very specific
pathways in the brain and spinal cord,» said Horner, who is also vice chairman of research
for the Department of Neurosurgery at Houston Methodist.
The endocannabinoid
system regulates energy homeostasis through G protein — coupled cannabinoid - 1 receptors5, 6 located in the central nervous
system and in various peripheral tissues, including adipose tissue, muscle, the gastrointestinal tract, and the liver.7 While peripheral cannabinoid - 1 receptor activation decreases adiponectin production in adipocytes, 8 central cannabinoid - 1 receptor activation in preclinical studies stimulates eating, decreases muscle, and stimulates hepatic and adipose tissue lipogenic
pathways in animal models of obesity.9 In genetic and diet - induced obesity, rimonabant, a selective cannabinoid - 1 receptor blocker, reduces overactivation of the central8, 10 and peripheral11, 12 endocannabinoid
system8, 10,13 and prevents weight gain and associated metabolic disorders, thus revealing a novel strategy
for the treatment of obesity and related cardiometabolic disorders.
Finally, the strategy applied here
for selective delivery of MK801 can be extended to other small molecules
for use in brain tissue (Tian et al., 2012), allowing
for an approach that combines chemistry, molecular genetics, and neurobiology to dissect cell signaling
pathways in specific cell types in the central nervous
system.