While novel treatment opportunities for heart disease, like microRNA therapeutics, are often effective,
systemic delivery induces a low cardiac exposure and can lead to undesirable effects in other tissues.
Not exact matches
Systemic delivery of TNF - related apoptosis -
inducing ligand (TRAIL) elevates levels of tissue inhibitor of metalloproteinase - 1 (TIMP - 1) and prevents type 1 diabetes in nonobese diabetic mice.
Ko IK, Ju YM, Chen T, et al., Combined
systemic and local
delivery of stem cell
inducing / recruiting factors for in situ tissue regeneration.