These may only produce local irritation, but some dogs have been reported to
develop systemic reactions to the different proteins present in the saliva of these biting flies.
My shadowrunner, Scully, would regularly scuttle between a good person caught a bad situation to an opportunistic scumbag The lack
of systemic reaction opened up avenues for roleplaying without worrying about if points were going up or down.
Some babies are more sensitive than others, and this chemical burn or reaction can range from redness everywhere the disposable diaper is touching, to severe burns and
even systemic reactions like rashes and eczema all over the baby's body!
Food allergies or sensitivities can adversely affect gastrointestinal mucosal integrity, increasing gut permeability to food antigens, which, in turn, can
produce systemic reactions by releasing proinflammatory substances that alter hepatic detoxification.
Because digestive enzymes in the gastrointestinal tract readily break down the food allergens, most commonly in fruits, vegetables, and nuts, the symptoms of OAS are typically limited to the oropharynx,
although systemic reactions may rarely occur.
This seemed to be
a systemic reaction to the UV - B stress, since even seed cones hidden among foliage died.
Even one tiny drop can create
a systemic reaction.
Most people with latex allergies experience only a localized reaction on the vulva or penis (contact dermatitis);
systemic reactions (like asthma or anaphylaxis) are rare.
Dr. Alessi's article is «Diagnosis Diagnosed:
A Systemic Reaction» published in Professional School Psychology, 3 (2), 145 - 151.