Sentences with phrase «systemic sclerosis»
Systemic sclerosis is a condition where the body's immune system mistakenly attacks healthy cells and tissues, causing the skin and internal organs to become thick and hard. It can lead to symptoms like skin tightening, joint pain, and difficulty breathing. Full definition
Different profile of cytokine production in patients with systemic sclerosis and association with clinical manifestations
efis.org
Molecular mechanisms leading to pDC dysregulation and persistent type I IFN signature are largely unexplored, especially in systemic sclerosis (SSc), a disease in which pDCs infiltrate fibrotic skin lesions and produce higher levels of IFNα as compared to healthy controls.
Scleroderma (also called systemic sclerosis) is a devastating autoimmune rheumatic disease which damages connective tissue.
Although the specific effects or consequences of FMc remain to be demonstrated in healthy women, FMc has been implicated in «alloimmunity» in some classically autoimmune diseases, for example systemic sclerosis and thyroiditis [8], [10]--[12].
They found fetal cells in the skin of women with scleroderma and in the spleens of women with systemic sclerosis, both autoimmune diseases.
Adipose - Derived Stem Cells: an Innovative Therapeutic Approach in Systemic Sclerosis and Parry - Romberg Syndrome (2014) in CellR4; 2 (1): e791.
According to the Scleroderma Foundation, «Scleroderma, or systemic sclerosis, is a chronic connective tissue disease generally classified as one of the autoimmune rheumatic diseases.
This research could also have an impact on other diseases such as systemic lupus erythematosus, systemic sclerosis and Crohn's disease.
If it affects internal organs, too, the patient is said to have systemic sclerosis, an often - fatal condition with no known cure.
The Tissue Platform workgroup within autoimmune inflammatory diseases at Karolinska Institutet studies the effects of probes in cell assays relevant for the diseases we study, ie systemic lupus erythematosus, idiopathic inflammatory myositis, systemic sclerosis and inflammatory bowel disease.
A connective tissue disease, systemic sclerosis, has also been associated with hypothyroidism.
The gene was found to be associated with a variety of autoimmune conditions such as type 1 diabetes, asthma, Addison's disease, myasthenia gravis, Sjorgren's syndrome, systemic lupus erythematosus (SLE), systemic sclerosis, ulcerative colitis and all forms of AITD including Grave's disease and Hashimoto's thyroiditis.
Correlation of articular involvement, skin disfigurement and unemployment with depressive symptoms in patients with systemic sclerosis: a hospital sample