Sentences with phrase «systemic use of»

SAP and SGPT (ALT) enzyme elevations, polydipsia and polyuria, vomiting, and diarrhea (occasionally bloody) have been observed following parenteral or systemic use of synthetic corticosteroids in dogs.

The systemic use of antibiotics and anti-fungal agents can also help.

Understanding the potential impact of the systemic use of coaching, the UF Lastinger Center has created, field - tested, and perfected a portfolio of research - driven coaching programs to advance learning in a range of areas and subjects and is offering access to them through a new Coaching Academy.

In this webinar moderated by Dr. Marty West of the Harvard Graduate School of Education, teams from Massachusetts, Tennessee, and Michigan presented their progress to date in establishing systemic use of research evidence, their ultimate goals, successful strategies, and the challenges and roadblocks they have faced.

Not exact matches

«The authorities are in a position to prevent systemic defaults,» said Fitch, including using the last resort of bailing out the LGFVs using fiscal resources.

«The commission will continue to stabilize the market and provide reassurance, and will use all its resources working toward the goal of preventing systemic risk.»

I calculated the level of democracy using the Polity dataset from the Center for Systemic Peace, which is the only data series on democracy that goes back to the mid-19th century.

Using systemic risk scores that evaluated size, interconnectedness, substitutability, complexity, and cross-jurisdictional activities, JPMorgan came in with the most dangerous score of 5.05 for U.S. mega banks.

As the three athletes prepared for the medal ceremony, Smith and Carlos wanted to use this opportunity to protest issues of systemic injustice in the United States in three distinct ways.

In this connection we can appreciate the need and significance of economics, literacy, computer literacy, use of media so as not to be brainwashed by the systemic forces, and dominant orthodoxies.

And if the academy acknowledged that religious intolerance is systemic and involves abuse of power, then its leaders would also have to acknowledge their tenuous position in relationship to the First Amendment, which says that the government will not use its power to «establish religion.»

After Iron Fist was rightly criticized for racial insensitivities, using the character's well - established comic book friendship with one of Marvel's most prominent black superheroes to directly confront systemic racism is a bold, smart move.

In the absence of a systemic analysis persons of goodwill can be (unwittingly) used by the powers that be for their benefit:

This month's spotlight is on Parenting Journey, an organization that recognizes that systemic stressors such as poverty, substance use, trauma, domestic violence, and immigration impact the mental wellness and the care provided to children, on top of the everyday stressors of parenting.

B Lab drives systemic change through three interrelated initiatives: 1) building a community of Certified B Corporations to make it easier for all of us to tell the difference between «good companies» and just good marketing; 2) accelerating the growth of the impact investing asset class through use of B Lab's GIIRS impact rating system by institutional investors; and 3) promoting supportive public policies, including creation of a new corporate form and tax, procurement, and investment incentives for sustainable business.

As with systemic analgesia, use of opioids in an epidural block increases the risk that your baby will experience a change in heart rate, breathing problems, drowsiness, reduced muscle tone, and reduced breastfeeding.

Today's sweeping indictments by federal and state prosecutors resoundingly confirm that the state's use of non-profits and SUNY to award billions in state economic development contracts has created huge and systemic opportunities for corruption.

Close to $ 2 Billion in public funds in play Today's sweeping indictments by federal and state prosecutors resoundingly confirm that the state's use of non-profits and SUNY to award billions in state economic development contracts has created huge and systemic opportunities for corruption.

«While we did not specifically investigate the use of force against the adult inmate population, our investigation suggests that the systemic deficiencies identified in this report may exist in equal measure at the other jails on Rikers,» prosecutors wrote in the report.

«Due to one - time events such as lower worker's comp costs, lower retirement costs, lower DGS costs from weather, but also some systemic changes from management, use of the ERP and timekeeping systems, which enabled the city to manage personnel costs better, city contracts and non-personnel costs better.»

As safety experts have told us and the U.S. Chemical Safety Board (CSB) explained in a groundbreaking 2011 report, the numerous laboratory incidents involving injury or death that we have sadly had to report in recent years almost always arise not from random mishaps, as the use of «accident» implies, but from specific and often systemic failures to observe accepted safety practices.

«Because of BX795's low toxicity, it has a great potential for systemic use as well as topical application.»

The new recommendations for systemic JIA are based upon more than 1,200 clinical scenarios and include recommendations for use of the following medications:

Venkatasubramanian, who is the Samuel Ruben - Peter G. Viele Professor of Engineering, Department of Chemical Engineering, and co-director of the Center for the Management of Systemic Risk, has long been interested in fairness and inequality and points out that the same concepts and mathematics used to solve problems in statistical thermodynamics and information theory can also be applied to economic issues.

Volunteers, ranging in age 40 to 80, were current or former smokers, and met one of the following other criteria: they used oxygen supplementation either currently or in the past, they were prescribed systemic corticosteroids and or antibiotics in the past year, or had been at the ER or hospitalized with a flare - up in the past year.

In 2006, the ASA released guidelines recommending the use of regional anesthesia, when possible, in patients with sleep apnea undergoing surgery to reduce the use of systemic opioids.

Researchers conducted a nationwide, population - based long - term observational cohort study using the Swedish Multi-Generation Register to monitor the risk of nonceliac autoimmune disease, which includes Crohn's disease, type 1 diabetes mellitus, hypothyroidism, hyperthyroidism, psoriasis, rheumatoid arthritis, sarcoidosis, systemic lupus erythematosus and ulcerative colitis.

Researchers used both animal models and human cells to demonstrate the hyper - responsiveness of MAIT cells to systemic exposure to bacterial superantigens.

The toxicity associated with the free - form version of the drug, he says, has prevented physicians from using the drug as a systemic treatment in people, one that can travel throughout the whole body.

«For our new systemic viral vectors — AAV PHP.S and AAV PHP.eB — there are many potential uses, from mapping circuits in the periphery and fast screening of gene regulatory elements to genome editing with powerful tools such as CRISPR - Cas9,» says Gradinaru.

In this study, by using a systemic mtEF4 gene knockout mouse model, researchers found that mtEF4 knockout damages the oxidative phosphorylation function in germ cells of male mice, thus causing male sterility.

It is the number one cause of systemic antibiotic use, which floods the whole body with antibiotics rather than just a specific region, said Rodrigo Bicalho, assistant professor of dairy production medicine at the College of Veterinary Medicine.

Nearly 80 million people in 77 countries received the influenza vaccine with WHO's help — including providing a «seed» strain of the virus used by manufacturers — but the report says that «numerous systemic difficulties» slowed distribution to low - resource countries.

Liver cirrhosis is a leading cause of morbidity and mortality, with complications such as HE resulting in recurrent emergency hospitalizations, irreversible brain injury, and a poor prognosis.2 - 5 There is some evidence that HE patients have a reduced relative abundance of certain beneficial gut microbiota (e.g. Lachnospiraceae and Ruminococcaceae) and an enrichment of potentially pathogenic Enterobacteriaceae ¬ - a microbial profile that has been linked to cognitive impairment and systemic inflammation in cirrhotic patients with HE.1 Faecal microbiota transplants have been used successfully to correct dysbiotic conditions such as recurrent Clostridium difficile and ulcerative colitis,6 - 8 and a preliminary report suggested that FMT may be promising in the management of HE.9

Systemic toxicity for the solenopsin derivatives has not been tested, but Arbiser says systemic toxicity would not necessarily preclude use in skin diseases, citing the example of external application of botulinuSystemic toxicity for the solenopsin derivatives has not been tested, but Arbiser says systemic toxicity would not necessarily preclude use in skin diseases, citing the example of external application of botulinusystemic toxicity would not necessarily preclude use in skin diseases, citing the example of external application of botulinum toxin.

The researchers found that the addition of vitamin D3 to ciclesonide did not significantly reduce the rate of first treatment failure (a composite outcome of decline in lung function and increases in use of beta - agonists, systemic steroids, and health care utilization) compared with placebo; 28 percent and 29 percent of participants in each group, respectively, experienced at least 1 treatment failure during 28 weeks.

«Our observations are of great clinical importance since IL -6-directed therapies are increasingly being used or studied to treat various human autoimmune conditions such as rheumatoid arthritis and systemic lupus erythematosus.»

The trio named SCIgen in honor of the World Multi-Conference on Systemics, Cybernetics, and Informatics (WMSCI), an annual event that they suspected was fraudulently claiming to use human peer reviewers to vet submissions.

Mice given a drug commonly used in patients to fight systemic fungal infections more often succumb to what would otherwise be a mild case of the flu.

It's hoped this latest insight will lead to the widespread use of antigen - specific immunotherapy as a treatment for many autoimmune disorders, including multiple sclerosis (MS), type 1 diabetes, Graves» disease and systemic lupus erythematosus (SLE).

Development of a vaccination protocol for mucosal use (HZI): Parenteral administration induces systemic protective immunity but is inefficient in inducing mucosal immunity, whereas mucosal administration can improve both systemic and local vaccine efficacy on mucosal tissues.

The HZI will develop a vaccination protocol for mucosal administration based on three novel strategies: (i) development and optimization of a vaccination protocol in which parenterally - primed T and B cells are subsequently pulled into the mucosa by the local delivery of the cognate antigen to the requested effector site, (ii) testing the co-administration of antigens with novel mucosal adjuvants using different mucosal immunisation routes and schedules, and (iii) testing various nanoparticles co-administered with different immunomodulators for their ability to generate both systemic and mucosal immune responses following transcutaneous / trans - follicular vaccination.

However, currently available probes that use this technology fail to maximize their specificity for tumours because of strong off - target signals, and thus, have limited ability to detect small tumours in a short timespan after systemic injection.

[21] In the recently presented FLAURA study, in which osimertinib was used in untreated patients with advanced EGFR - mutant NSCLC, the HR for systemic disease control and CNS control similarly favored osimertinib over erlotinib or gefitinib, supporting the preclinical data that showed osimertinib's penetration across the BBB and providing support for using this agent in first - line management of EGFR - mutant patients with brain metastases.

Other studies have looked at PD - L1 expression as a prognostic variable and in the context of response to systemic therapy and used a cut point of percentage positivity of ≥ 5 %.

(It should be noted that the knockdown of the TOR pathway in the fat body severely affects larval growth [8]; therefore, Lsp2 - GAL4, which is expressed in the fat body at the wandering stage — after the growth period [13]-- was used to overexpress TSC1 / 2 in order to avoid secondary effects from a systemic growth defect.)

In a study involving 12 patients with bladder cancer, who also underwent prostate surgery as part of their treatment, she identified the ICOS molecule as the first immunologic marker identified in both tumor tissues and the systemic circulation that can be used as a biomarker for monitoring of anti-CTLA-4 treated patients as a possible marker of therapeutic activity.

This pure cell preparation is used in the systemic treatment of heart disease and other conditions such as inflammatory arthritis, autoimmune diseases and neurological disorders.

The authors use the official term SEID (systemic exertion intolerance disease), which was recommended by an Institute of Medicine panel in 2015, but hasn't really stuck among those in the ME / CFS field.

FDA Approved Ibrutinib for Relapsed, Refractory Marginal Zone Lymphoma: Approval for the use of ibrutinib in patients with relapsed or refractory marginal zone lymphoma was granted by the US Food and Drug Administration for those patients who require systemic therapy who were treated with at least one anti-CD20 therapy.