Sentences with phrase «systems biology approach»

Our primary research theme is to study scientific questions using integrated systems biology approaches.

The scientists used a comprehensive systems biology approach to explore the relationship between genes, low - dose radiation, and cancer.

There are also opportunities to explore cancer biology through systems biology approaches.

From correlation to causation: analysis of metabolomics data using systems biology approaches — Antonio Rosato, Metabolomics

The grant will also support a biotechnology symposium and workshop every summer, which will include training students in systems biology approaches to applying multiple genomics technologies and integrating large amounts of data.

His group is now blending large - scale systems biology approaches with mechanistic and structural biochemistry to systematically annotate the functions of these mitochondrial proteins, including many that harbor causative mutations in human disease.

ISB's Connection: With a mission to tackle biological complexity, ISB has pioneered systems biology approaches that put our scientists and collaborators in a prime position to take on the challenge of demystifying the brain.

In the research community, we've got to develop systems biology approaches, such as this one, that take a more sophisticated approach to get us where we need to be.»

New institutions around the world are gathering interdisciplinary teams of biologists, mathematicians, and computer specialists to help promote systems biology approaches.

The National Institutes of Health has awarded Virginia Tech researchers a $ 2.13 million grant to develop new systems biology approaches to study cells, one of the most basic units of life.

Using the replicative aging of the yeast Saccharomyces cerevisiae as an aging model, we will apply quantitative systems biology approaches to investigate: 1.

Specifically, the genome - wide systems biology approaches to dissect the epigenetic processes that become abnormal when aggressive prostate cancer and melanoma initiates, rather than the reductionist «gene - by - gene» classical approaches, are urgently necessary.

Specifically, the authors call for systems biology approaches (using large data sets and modeling to understand complex biological systems) to fill critical knowledge gaps in understanding how Mycobacterium tuberculosis (Mtb) infection causes disease.

CP: Participants in the ISB summer course will gain experience using systems biology approaches that allow them to carry out personalized medicine.

The systems biology approach, where cross-disciplinary scientists work together as a team, can potentially make important contributions to research.

Michael Katze, University of Washington microbiology professor and lead investigator for collaborative NIH programs that use systems biology approaches to investigate viral - host interactions, puts it bluntly: «The NIH is impatient with basic science,» he says.

Borenstein and his team use a systems biology approach and apply sophisticated computer modeling to understand the structure, function, and dynamics of the microbiome.

But the changing world of drug safety also requires that scientists adopt a systems biology approach.

«We should use a systems biology approach to look at entire pathwaywide or organismwide analysis at a systems level, to understand how individual genes, proteins and other components work together to regulate a property or a behavior.»

The Center has pioneered the systems biology approach to research, which utilizes state - of - the - art technology, fosters collaboration between scientists, and allows for a comprehensive understanding of the interactions between pathogens and their hosts.

There are ongoing studies which focus on the discovery of molecular biomarkers of the VSV - ZEBOV vaccine in healthy individuals using omics - based technologies in combination with a systems biology approach,» says Ali Harandi.

By using a systems biology approach, researchers deliberately move away from the classic reductionist manner of looking at molecules in isolation to study biological systems in their entirety.

As analytical devices continue to improve and bioinformatics systems get more powerful, yet easier to use, systems biology approaches will stretch across more areas.

Metabolic phenotyping and systems biology approaches to understand neurological disorders

The resulting data are being combined in a systems biology approach with high - resolution clinical phenotyping and findings obtained with a large array of established and novel in vitro, ex vivo and in vivo disease models to identify disease - associated genetic variants, disease - defining molecular signatures, and potential targets for therapeutic intervention.

Krogan, a UCSF professor of cellular and molecular pharmacology and a senior investigator at the Gladstone Institutes, is known for his research into developing and using systems biology approaches to help understand complex biological phenomena at a mechanistic level.

The title of Dr Dimas's grant is «A genomics and systems biology approach to explore the molecular signature and functional consequences of long - term, structured fasting in humans».

Dissecting these interactions with a combination of cell - biology and systems biology approaches should allow uncovering the tissue specific control mechanisms that are defective in cancer.

«Pregnancy complications are not very well understood, and we are amongst the only labs really taking a systems biology approach to this kind of research,» Alison explains.

Using a systems biology approach, scientists uncover important general principles of glioblastoma tumor evolution.

In this project, we seek to combine modern techniques in a systems biology approach using species - specific in vivo labeling tools (monoclonal antibodies and fluorescent protein - expressing bacteria), monitoring of acid production (pH - sensitive dyes, fluorescent proteins and metabolite profiling), as well as ecology based approaches such as labeling of acid active species with stable isotope probing (SIP) combined with deep 16S rRNA pyrosequencing.

The systems biology approach often involves the development of mechanistic models, such as the reconstruction of dynamic systems from the quantitative properties of their elementary building blocks.

The systems biology approach is characterised by a cycle of theory, computational modelling and experiment to quantitatively describe cells or cell processes.

A systems biology approach integrating genome ‐ wide genetic variation and transcriptome profiling data from participants of the Framingham Heart Study identifies key regulatory genes and gene networks underlying blood pressure control.

Founded on the belief that food can transform lives, one plate at a time, Habit is the first company to provide personalized nutrition recommendations based on a systems biology approach.

Functional medicine reflects a systems biology approach to health care: a comprehensive analysis of the manner in which all components of the human biological system interact functionally with the environment over time.

The intensive year - long instruction combined a systems biology approach to health with an in - depth concentration on root cause of disease, coupled with therapeutic dietary treatment, and stress management techniques.

She has also started her training with the Institute for Functional Medicine which teaches healthcare professionals to get to the root cause of lifestyle - driven disease through a patient - centered, systems biology approach.

Her ongoing clinical training through the Institute for Functional Medicine uses a systems biology approach when working with those who suffer from chronic and acute conditions to help them find their path to healing.

Functional medicine uses a systems biology approach, which is a study of how our body's biological systems interact functionally with environment over time.