Sentences with phrase «systems biology tools»

According to Dr Adil Mardinoglu, SciLifeLab Fellow and leader of the systems biology effort in the project: «We are now in possession of incredibly powerful systems biology tools for medical research, allowing, for the first time, genome - wide analysis of individual patients with regards to the consequence of their expression profiles for clinical survival.»
He then laid out his strategy for figuring out how to take advantage of the tumor - targeting T cells that patients already possess, and stressed the need for improved systems biology tools, including the ability to perform automated, high throughput analyses to perform deep interrogations into patients» T cell repertoires.

Not exact matches

Systems biology, biochemistry, synthetic chemistry, microbiology, and enzymology, along with evolutionary, bioinformatics, and biocomputational tools may also all be the cornerstone of your work, depending on the specific field you're working in.
The authors believe that these tools and methods will lay the foundation for crucial breakthroughs in the flatworm model system and in our understanding of stem cell biology and the process of regeneration.
Fundamental discoveries in biology have yielded powerful tools for the study of human biological systems.
CRISPR (pronounced crisper) burst on the scientific scene in 2012, when researchers transformed what had originally been identified as a rudimentary immune system in bacteria into one of the most powerful tools in molecular biology.
«The purpose of the paper was to provide the detailed recipes and protocols so that others can easily duplicate the work and help to further permeate the idea of «building with biology» — so that other researchers and educators can have the tools and the knowledge to build these bio-hybrid systems and attempt to address challenges in health, medicine, and environment that we face as a society,» stated Rashid Bashir, a Grainger Distinguished Chair in Engineering and head of the Department of Bioengineering at Illinois.
However, lipids provide a useful tool for systems biology, because «they can be quantified, which tells us about the state of a cell or tissue,» explains Kai Simons, CEO of Lipotype in Dresden, Germany.
The advent of molecular cloning, DNA sequencing and the many tools of molecular genetics and cell biology has given us sufficient knowledge of the basis for disease and the genes to target, but what has limited the application of gene therapy has been efficient gene delivery systems.
«This cellular system provides a very important and exciting tool for understanding the biology of human brown fat tissue.
His main responsibilities are the development of novel software tools and algorithms for the Virus Pathogen Resource (ViPR) and Influenza Research Database (IRD), as well as research on the comparative evolutionary genomics and systems biology of viruses.
NEW YORK and SEATTLE — April 5, 2018 — The Cancer Research Institute (CRI), Institute for Systems Biology (ISB) and Sage Bionetworks — three organizations on the forefront of cancer immunotherapy, systems biology and bioinformatics — today announced the release of the Cancer Research Institute iAtlas, a comprehensive web - based tool that allows oncologists and researchers to study and analyze interactions between tumors and the immune microenvirSystems Biology (ISB) and Sage Bionetworks — three organizations on the forefront of cancer immunotherapy, systems biology and bioinformatics — today announced the release of the Cancer Research Institute iAtlas, a comprehensive web - based tool that allows oncologists and researchers to study and analyze interactions between tumors and the immune microenvirsystems biology and bioinformatics — today announced the release of the Cancer Research Institute iAtlas, a comprehensive web - based tool that allows oncologists and researchers to study and analyze interactions between tumors and the immune microenvironment.
Recognizing the reality that genomics analysis is a big data / HPC (High Performance Computing) problem in a field where life scientists are focused on the biology and not computer science, Intel has been reshaping genomics software tools and cluster configurations for life sciences in the many - core era with Intel Scalable System Framework (includes many - core processors, new 3D memory, high - performance networking fabric, and Lustre storage).
The Bergthaler laboratory pursues an integrative approach comprising infection models and tools of immunology, pathology and systems biology in order to dissect novel disease - relevant interactions between pathogens and the host.
Working with the infectious disease scientific community, his team developed functional genomics tools and datasets to advance ways in which systems biology is leveraged to characterize emerging and biodefense threat - related pathogens.
The rapid progress in developing Cas9 into a set of tools for cell and molecular biology research has been remarkable, likely due to the simplicity, high efficiency and versatility of the system.
Currently, researchers have access to powerful tools in biology to help them understand the ocean, such as microscopy and DNA sequencing, but are lacking essential tools in genetics to make robust experimental model systems.
Rapid developments in the field of synthetic biology and its associated tools and methods, including more widely available gene editing techniques, have substantially increased our capabilities for bioengineering — the application of principles and techniques from engineering to biological systems, often with the goal of addressing «real - world» problems.
Krogan described the CCMI as a «cross-UC program focused on using quantitative systems tools to help understand the underlying biology behind the genomic data derived from breast, head and neck, and other cancers.»
His research interests belong to pushing frontiers of microscopy for cell biology, developing of new microscopical tools, systems and approaches.
This two - volume reference integrates this exciting area of biology, combining the prerequisites for a general understanding of adult and embryonic stem cells, the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations, as well as a presentation by the world's experts of what is currently known about each specific organ system.
Their next step is to continue to rework HipMCL and other computational biology tools for future exascale systems, which will be able to compute quintillion calculations per second.
An in vivo - vitro shuttle system for the study of P. cynomolgi liver stages12 is being exploited to better understand hypnozoite biology using molecular tools and genome - scale approaches, which rely on the availability of a complete and well annotated P. cynomolgi reference genome sequence.
Our goal is to provide intuitive bioinformatics tools for the visualization, interpretation and analysis of pathway knowledge to support basic research, genome analysis, modeling, systems biology and education.
While synthetic biology may be a useful tool in helping to better understand biological systems, it carries too many risks and unanswered questions to be allowed outside the lab at this time.
These tools can be rapidly adapted to meet the current and future demands of systems biology, such as data management systems designed to support the seamless mining and analysis of biological data.
Specifically, Dangl and his team investigate how the plant immune system discriminates between microbial friend and foe in a complex environment, using tools and techniques from genomic, structural, cellular, and molecular biology.
Techniques used in systems biology The defining feature of System Biology is the ability to obtain, integrate and analyze complex data from multiple experimental sources using interdisciplinary tools.
To improve fuel production titer, rate, and yield (TRY), we study the producing host and fuel biosynthesis pathway intensively using various functional genomics tools such as targeted proteomics, metabolomics, and transcriptomics, and engineer the metabolic pathway in the producing host using synthetic biology tools and systems biology.
In 1996, she started the Center of Excellence for Breast Cancer Care at UCSF to integrate clinical care and research, automate tools for the capture of patient and clinical data, and develop systems to tailor care to biology, patient preference, and performance.
«With this (technology), the center will provide the biology research community with tools to study an enormous number of biological systems that are currently inaccessible by current X-ray methods,» says NSF Chemistry of Life Processes Program Manager David Rockcliffe.
During the course of the project, the network furthered tools and strategies to make available to the wider research community, a new approach to the systems biology of the living cell.
Network science is a powerful tool for analyzing complex systems in fields ranging from sociology to engineering to biology.
The law CHAPTER 2: BIOLOGY OF DOGS Physiological characteristics Reproductive system CHAPTER 3: BASIC HEALTH Signs of a healthy dog Recognising poor health Common internal parasites Common external parasites Common disease and illness Skin problems in dogs Notifiable diseases Preventative health care & care of the sick dog Good nutrition Reproduction and breeding Desexing CHAPTER 4: PSYCHOLOGY Understanding the dog's mind Evolution and domestication Behavioural development Common behaviour and body language Behavioural problems General training tips CHAPTER 5: GROOMING The need for grooming Techniques Grooming tools Pet clips and styling CHAPTER 6: WORKING IN THE CANINE INDUSTRY Health services Breeding Grooming Training Day care & exercise Long term care Assistance dogs Canine therapy Professional dog handling Retail Funeral and memorial services APPENDIX Love Dogs?
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