Sentences with phrase «take on cancer cells»

It's a type of cancer immunotherapy, which harnesses the body's immune system to take on cancer cells.

Not exact matches

Basically, CAR - T therapy involves taking a patient's own immune «killer» T - cells, inserting new genetic code into those cells which turn them into cancer - hunters that can home in on malignant B - cells (another kind of immune cell), and then pumping these specialized leukemia - busting cells back into the patient.

The treatment is a type of so - called CAR T - cell therapy — taking a patient's own immune cells, called T cells, genetically manipulating them to attack specific proteins on cancer, and infusing them back into the patient.

In order to find out how and why ovarian cancer cells grow and take on such lethal characteristics, Dr. Shepherd and his team grow the cancer cells in 3D structures, called «spheroids» — the same way the cancer cells grow in patients.

Lab testing showed that the plant - made virus particles, which naturally bind to receptors on cancer cells, were taken in by human breast cancer cells.

Using this biosensor in highly invasive breast cancer cells taken from rodents and humans, the Einstein team discovered that when an individual invadopodium forms and is actively degrading the ECM, its Rac1 levels are low; on the other hand, elevated Rac1 levels coincide with the invadopodium's disappearance.

«If cancer recurs, it may be because the therapy didn't hit key mature cells that take on stem cell - like behavior.

«We began with stem cells taken from cord - blood, which have fewer acquired mutations and little, if any, epigenetic memory, which cells accumulate as time goes on,» says Zambidis, associate professor of oncology and pediatrics at the Johns Hopkins Institute for Cell Engineering and the Kimmel Cancer Center.

As cell phones and smart phones take over more communication, information and entertainment functions, concerns about their possible role in causing brain cancer are buzzing on the airwaves.

Banik cautions that neither of the contrast agents has yet been tested on animals injected with breast cancer cell lines, which he calls an important step to take.

The team worked on tissue from three patients with colorectal cancer, taking normal bowel stem cells and cells from four different areas of the tumours.

Other possible ways to attack pancreatic cancer cells focus on taking away their ability to hide from the immune system.

«The focus of chemotherapy and existing standard - of - care is on killing cancer cells but instead we took a completely different approach which changes the environment the cancer cells live in,» said Mick Bhatia, director and senior scientist with the McMaster Stem Cell and Cancer Research Institute, who led the group that performed the cancer cells but instead we took a completely different approach which changes the environment the cancer cells live in,» said Mick Bhatia, director and senior scientist with the McMaster Stem Cell and Cancer Research Institute, who led the group that performed the cancer cells live in,» said Mick Bhatia, director and senior scientist with the McMaster Stem Cell and Cancer Research Institute, who led the group that performed the Cancer Research Institute, who led the group that performed the study.

Most forms of cancer resemble evolution happening on an accelerated timescale, with a sudden explosion of genetic rearrangements taking place in the cells.

The disabled gene codes for the protein PD - 1, which normally puts the brakes on a cell's immune response: cancers take advantage of that function to proliferate.

But once cells become malignant, PDX1 takes on a new role and contributes to the cancer's growth.

Now, University of Pennsylvania researchers have revealed how a reduction in mitochondrial DNA content leads human breast cancer cells to take on aggressive, metastatic properties.

But a computer game that puts those kids on the front line of a battlefield inside the human body — where cancer cells and chemotherapy drugs are slogging it out for supremacy — just might persuade them that it's important to keep taking the drugs.

Furthermore, when the team, lead by cell biologist Valeria Fantin, implanted LDH - A-normal cancer cells and LDH - A-deficient cancer cells in mice, LDH - A-deficient tumors grew more slowly and took two - and - a-half times longer, on average, to kill the mice than LDA - A-positive tumors.

While past attempts to treat melanoma failed to meet expectations, an international team of researchers are hopeful that a compound they tested on both mice and on human cells in a petri dish takes a positive step toward creating a drug that can kill melanoma cancer cells without harming nearby healthy cells.

The scientists took the genes for the most effective liver cancer antigen receptors on those T cells, put those receptors on human T cells and the resulting engineered human T cells eradicated the cancer as well, without hurting normal liver cells, they report in the journal Hepatology.

When normal cells are transformed into cancer cells, this epithelial tissue can take on the characteristics of embryonic tissue, known as mesenchymal tissue, which is comprised of unspecialized cells that will develop, as the embryo matures, into more specialized tissues.

Unlike other studies on p53, however, which target cell populations that average many cells together, Dr. Lahav developed a new approach, quantifying p53 at high temporal resolution in single cells and taking into account that «individual cell decisions are crucial in the development and treatment of cancer.»

Before long, the cancer cell is abnormal enough that it takes on behaviors that eventually kill us.

By binding to and blocking certain molecules on T cells, in this case a molecule called PD - 1, pembrolizumab «takes the brakes off» the immune response, allowing a more powerful response to cancer.

Once taken up by antigen - presenting cells, which help focus the immune system on an invader, the vaccine releases a factor that heightens their attention specifically to the cancer - promoting protein E7, a so - called oncoprotein that not only enables the human papillomavirus to multiply, but potentially cervical cancer cells to do the same.

For instance, «we're seeing relapses despite the fact» that T cells have swarmed a tumor and taken aim at molecules on the malignant cells, said Greenberg, who is also the head of immunology at the Fred Hutchinson Cancer Research Center.

A team at the University of Leeds has discovered that shaping gold nanoparticles in the form of minuscule tubes sees them take on a number of new properties, including the ability to be heated up to destroy cancer cells.

The U.S. drug maker released a statement on Monday saying that its Keynote - 010 study, a randomized Phase two - third trial, showed that patients who were taking two different doses of Keytruda (FDA - approved two mg / kg dose and treatment dose of 10 mg / kg given every three weeks) had longer survival compared to those who took docetaxel, the drug widely used for non-small cell lung cancer (NSCLC).

Fact # 3: The technology that conventional medicine uses to detect cancer in various parts on the body is based on a PET scan (Positron Emission Tomography), which takes advantage of cancer cells» voracious appetite for sugar.

This is a photomicrograph — a photograph taken under a microscope of an actual breast cancer cell, which then divides, and becomes two cells, and then four, eight, and so on.

Some cancers develop mutations that serve the purpose of increasing the influence of insulin on the cell; others take advantage of the elevated insulin levels that are common to metabolic syndrome, obesity and type 2 diabetes.

A «WOW» maple syrup finding: Take this 2015 study reported in Oncology Reports: the researchers examined the effect of three grades of maple syrup (grades are based on the color of the syrup and ranges from light to darker with color being influenced by time of year and processing technique) on the proliferation, migration, and invasion of colorectal cancer (CRC) cells in order to investigate whether maple syrup is suitable as a phytomedicine for cancer treatment.

When we take into account that «50 to 70 percent of our total immune system cells can not see cancer... even on our best day,» A.J. Lanigan said, the notion of adding it to our diet seems even more blasphemous.

A study funded by the US Public Health Service studied the effects of pomegranate juice on prostate cancer cells taken from patients and determined that pomegranate extract was able to slow down the growth of cancer in these cells.

Those are cells that were taken from nun many years ago that had breast cancer and they propagated them and they do a lot of the research on this line of cells that actually came from a nun that had breast cancer called MCF - 7 estrogen dependent breast cancer.

Taken as a whole, we are not surprised by the hallmark impact on cancer prevention made by cruciferous vegetables, or the potential of this food group to modify activities in cells that have already become cancerous.

Since these experiments were only performed on cancer cells in test tubes, the researchers took the next step and ran tests on breast cancer tumors in live mice.

The radiation can destroy the thyroid gland and any other thyroid cells (including cancer cells) that take up iodine, with little effect on the rest of your body.

When it comes down to it, the holistic approach involves taking into account whole - body function and not just focusing on killing cancer cells and can improve a pet's clinical response to treatment.