Sentences with phrase «tamoxifen for»

However, I have been on Tamoxifen for almost 4 years, with instructions to avoid any phytoestrogens, so have been avoiding soy in all forms, flax seeds, pumpkin, sweet potatoes, etc..

This would include using 50mg / day of clomifene for 4 weeks and 20mg / day of tamoxifen for 4 weeks starting one week after ending the cycle.

Some said it could just be a «statistical fluke» and pointed out that none of the women who took Tamoxifen for one to four years developed a new tumor.

«So, medical doctors, traditional doctors will recommend five to 10 years of hormone suppressing drugs, like tamoxifen for example,» Dr. V says.

Tamoxifen may not be right for older women You can expect to take any of these drugs once a day for five years — although a 2007 study in the journal Cancer suggests that tamoxifen may be on its way out for breast cancer survivors who've passed menopause: Two multicenter trials found that when women who'd been taking tamoxifen for two or three years switched to an AI, their survival rates significantly improved compared with continuing on with tamoxifen.

The researchers say that breast - feeding could be the equivalent of taking the drug tamoxifen for 5 years, which is a well - known way to cut breast cancer risk in women with a family history of the disease.

The results of the IBIS - II DCIS trial show that anastrozole is as effective as tamoxifen for this type of breast cancer and could offer a new treatment option for post-menopausal women.

The study looked at 2,980 postmenopausal women with DCIS in 14 countries, who were either given anastrozole or tamoxifen for five years after surgery.

Not exact matches

Hi I'm currently recovering from breast cancer, and chickpeas are not recommended for those on tamoxifen.

Kontos adds that a greater role for aspirin would be welcomed by many at - risk patients, as current drugs aimed at reducing risk, such as tamoxifen and raloxifene, have significant side effects and do not prevent ER - negative breast cancer.

But unlike tamoxifen, bazedoxifene has some of the properties of a newer group of drugs, known as selective estrogen receptor degraders, or SERDs, which can target the estrogen receptor for destruction.

Gerry Potter and Ray McCague of the Institute of Cancer Research in Surrey based their design strategy on tamoxifen, a drug widely used for treating breast cancer.

Standard treatments for ER + breast cancer are endocrine therapies such as tamoxifen and aromatase inhibitors.

«Never before has PTK6 inhibition been shown to inhibit growth and induce cell death of ER + breast cancer cells, including those resistant to standard treatments for this subtype such as tamoxifen,» said Hanna Irie, MD, PhD, Assistant Professor of Medicine (Hematology and Medical Oncology) and Oncological Sciences at The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, and senior author of the study.

«These results indicate that tamoxifen is a pharmacologically attractive scaffold for the development of new anti-cryptococcal drugs and provide a mechanistic base for its further optimization.»

«This means that tamoxifen, which is probably the best therapy for breast cancer available, is not working solely through blocking the oestrogen receptors, which everyone thought it did.

«This work sets the stage for additional animal studies to see if tamoxifen can be used as a drug in people and will allow us to design new drugs related to tamoxifen that are better antifungals,» says Damian Krysan of the University of Rochester, an author on the study.

The debate over the tamoxifen trial centres on the need to balance the risks of developing breast cancer with the possible risks to healthy people of taking a drug for many years.

But more importantly, because of their very different side - effects, anastrozole can be offered as an alternative for patients who may not tolerate tamoxifen as well or have previous illnesses making tamoxifen unsuitable.

Highly dependent on their estrogen receptors for growth and survival, these tumor cells are sensitive to hormonal therapies, making drugs like tamoxifen and fulvestrant effective first - line therapies for many patients.

Letrozole is approved by the FDA for the adjuvant treatment of early - stage breast cancer in postmenopausal women who have already been treated with 5 years of tamoxifen therapy.

Tamoxifen has been used for decades to treat breast cancer and has recently been shown to prevent breast cancers in many women.

Dr Julie Sharp, senior science information manager at Cancer Research UK, said: «These early results tell us more about why tamoxifen can stop working for some women.

All had taken letrozole for about 5 years; some also had been treated previously with tamoxifen.

The well - known breast cancer drug Tamoxifen, for example, blocks a tumor's ability to use estrogen.

For example the researchers used the CRE - ERT2 mouse model validated at the ICS, in which Cre function is controlled by the promoter of Atypical Notch ligand Delta - like homologue1 (Dlk1) under Tamoxifen activation, a skin fibroblast marker, to carry out temporal and tissue specific inactivation of key genes involved in skin fibroblast diversity.

It was used in this study for the first time to study factors that cause estrogen receptor positive breast cancer to recur during tamoxifen therapy.

«We have found that the same genes responsible for tamoxifen resistance in our animals are also turned off in human breast cancer cells that do not respond to the drug,» she says «Because these genes were epigenetically silenced — meaning they were not irreversibly altered, just switched off — it was possible to turn them back on.

The 2nd session provided an overview of cases, as evidence for clinical use of pharmacogenomics, focusing onTPMT genotyping for thiopurine treatment (Dr. Marieke Coenen, Radboud University, Nijmegen, the Netherlands), DPYD genotyping (Dr. Linda Henricks, Netherlands Cancer Institute (NKI), Amsterdam, the Netherlands), tamoxifen and CYP2D6 genotyping (Prof. Matthias Schwabb, Margarete Fisher Bosch Institute, Stuttgart, Germany) and SLCO1B1 and statin pharmacogenomics (Prof. Mikko Niemi, University of Helsinki, Helsinki, Finland).

For confirmation, we exploited the flexibility of our system, enabling tamoxifen inducible conditional gene ablation while controlling for genetic background and tamoxifen effecFor confirmation, we exploited the flexibility of our system, enabling tamoxifen inducible conditional gene ablation while controlling for genetic background and tamoxifen effecfor genetic background and tamoxifen effects.

(K) Representative FACS plots of the type in I for cells from a 2 - day tamoxifen - treated S1pr1f / f CreERt2 mouse.

Researchers at Karolinska Institutet in Sweden have developed a method for assessing the effect of tamoxifen, a common drug to prevent the relapse of breast cancer.

For severe cases, doctors sometimes prescribe Danazol, a steroid derivative that decreases levels of the reproductive hormones FSH and LH, or tamoxifen, a breast - cancer drug that helps relieve breast pain by blocking estrogen receptors, thus preventing estrogens effect on breast tissue.

â $ There are two drugs approved for reducing your risk of getting breast cancer: raloxifene, which is approved for use in postmenopausal women, and tamoxifen, which is approved for all ages, â $ explains Dr. Gralow.

«Tamoxifen can cause vaginal bleeding and increase risk for endometrial cancer, so we make sure breast cancer patients [taking it] see a gynecologist on a regular basis,» says Dr. Andrews.

This rate compares favorably with hormonal treatments such as tamoxifen given as a preventive measure to women at high risk for breast cancer.

Second, tamoxifen — one of the most commonly prescribed breast cancer drugs (its also used preventively by some high - risk women)-- may have heart - protective effects for breast cancer patients and survivors, according to some research.

And in March 2008, researchers announced that drugs in a newer class called aromatase inhibitors (AIs) stopped breast cancer recurrence for postmenopausal patients who had completed tamoxifen treatment (even years after).

Tamoxifen is the number one medical drug for reducing male breasts, and it's very effective.

Dietary estrogens in the form of soy foods were found to have the potential to disrupt the endocrine system with the effects in women similar to taking the breast cancer drug tamoxifen (Proceedings of the Society for Experimental Biology and Medicine 1995 Jan; 208 (1): 51 - 9).

But for women who are taking tamoxifen and want to continue, yes, physiologic doses of transdermal progesterone are compatible with tamoxifen.

The drug tamoxifen, for instance, helps many women with breast cancer, but they pay the price of an increased risk of endometrial cancer.1 Medicine would do much better concentrating on genuine prevention — especially through nutrition.

Rather than wait and see for two long years only to resort later to drugs designed for breast cancer like tamoxifen and raloxifene or surgical reduction does not seem like a health promoting plan of action particularly for a young boy possibly already struggling with self esteem issues.

May require slightly different dosages for drugs such as tamoxifen, warfarin, fluvastin, and many nonsteroidal anti-inflammatory agents such as aspirin, ibuprofen and naproxen.

For example, the anti-estrogen drug tamoxifen, prescribed for breast cancer treatment, has been used by men to oppose the estrogenic effects of anabolic steroiFor example, the anti-estrogen drug tamoxifen, prescribed for breast cancer treatment, has been used by men to oppose the estrogenic effects of anabolic steroifor breast cancer treatment, has been used by men to oppose the estrogenic effects of anabolic steroids.

Tamoxifen often is prescribed as part of the treatment for ER + breast cancer.

For instance, if your doctor is recommending you take an estrogen inhibitor such as Tamoxifen, the book can help you weigh the pros and cons of using such drugs as well as chemotherapy, radiation, and other treatment options.

If you're diagnosed with high estrogen levels or if you're high - risk for estrogen - dependent cancers, your doctor may prescribe Tamoxifen.

For instance, the antidepressant Effexor may be a better choice for women taking tamoxifen because it appears to interact the least with this hormone - blocking drug, he saFor instance, the antidepressant Effexor may be a better choice for women taking tamoxifen because it appears to interact the least with this hormone - blocking drug, he safor women taking tamoxifen because it appears to interact the least with this hormone - blocking drug, he says.

New Drug Therapies for Breast Cancer Tamoxifen has been used for twenty years in the treatment of advanced breast cancer.