Researchers refer to such an idea as a gene BY environment interaction — such that different environments work in
tandem with our genes to lead to various outcomes.
Not exact matches
Recent research also has illuminated how the deadly cascade that leads to brain atrophy is set in motion: The buildup of amyloid plaques, working in
tandem with certain
gene mutations, sparks the formation of the renegade tau proteins.
The researchers say that the
genes ASF1A and OCT4 work in
tandem with a ligand, a hormone - like substance that also is produced in the oocyte called GDF9, to facilitate the reprogramming process.
The causative mutation was a repetition of a piece of non-coding DNA, a so called
tandem repeat, in a
gene with an unknown function, named C9orf72.
Although none of the German Neolithic samples carries the copy number expansion of the AMY2B
gene associated
with starch digestion, we find that this
gene is present in three copies in NGD, though this is due to a large segmental duplication that is shared
with multiple modern dogs, an event separate from the
tandem AMY2B duplications.
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A Hex cDNA
with a recognition sequence for bacterial BirA ligase was linked via an artificial IRES consisting of a
tandem array of repeated Gtx sequences to the
gene encoding Venus followed by a cytomegalovirus driven hygromycin - thymidine kinase dual selection cassette flanked by loxP sites.
Depending on the technical details, the process replaces one version of the
gene with another or adds another copy of the
gene in
tandem.
Another important factor in reading and writing disabilities, READ1, a polymorphic compound
with a short
tandem repeat within intron 2 of risk
gene DCDC2 may have a non-additive genetic interaction
with KIAHap, a risk haplotype in risk
gene KIAA0319 may be a transcriptional regulator of ETV and so also a transcriptional regulator of KIAA0319.
Moreover, a variable number of
tandem repeat in the 3 ′ UTR of the SLC6A3
gene is associated
with various antisocial behaviors such as violent delinquency [91] and propensity to a criminal career [92].
Fowler et al. (2009) found that a variable number
tandem repeat (VNTR) polymorphism in the
gene encoding monoamine oxidase A (responsible for catabolism of serotonin and other catecholamine neurotransmitters), and an insertion / deletion polymorphism in the SLC6A4 promoter (5 - HTTLPR) were associated
with what the authors term the «emotional dysfunction» aspect of psychopathy (a construct that corresponds
with CU traits) in a sample of adolescents
with attention deficit hyperactivity disorder (ADHD)[18].