Thanks to this state - of - the - art telescope, we can observe
the target at higher frequency and higher resolution.
Not exact matches
By using engineered zinc - finger nucleases (ZFNs) designed to
target an integrated reporter and two endogenous rat genes, Immunoglobulin M (IgM) and Rab38, we demonstrate that a single injection of DNA or messenger RNA encoding ZFNs into the one - cell rat embryo leads to a
high frequency of animals carrying 25 to 100 % disruption
at the
target locus.
«But, if we miss those
targets, the increase in
frequency and intensity could be much
higher,» said Karin van der Wiel, a postdoctoral researcher
at the Royal Netherlands Meteorological Institute (KNMI) in De Bilt, Netherlands and a co-author of the new ERL paper.
This study demonstrates just how easy it is to drive a trait to a
high frequency in an evolutionary blink of an eye, and suggests that simply because a domestic trait is ubiquitous, it may not have been a
target for selection
at the very beginning of the domestication process,» said author Greger Larson.
The first three sets included
targets that appeared
at a low
frequency, the fourth set had
targets appear
at a
high frequency with feedback to let the observers know if they had been right or wrong and the fifth set of bags had
targets appear
at a low
frequency again.
Overall, the X4 - ZFNs are highly specific for cxcr4 with low
frequency disruption clearly seen
at 2 of 15 putative off -
target sites with the
highest homology to the intended
target.
«But, if we miss those
targets, the increase in
frequency and intensity could be much
higher,» said Karin van der Wiel, a postdoctoral researcher
at the Royal Netherlands Meteorological Institute (KNMI) in De Bilt, Netherlands and a co-author of the new ERL paper, who will also be presenting the new research
at a press conference today
at the AGU Fall Meeting.
from the University of Washington reported a surprising finding - when delivered via AAV infection, gene
targeting vectors with relatively short (1 kb) homology arms underwent homologous recombination
at a
frequency three orders of magnitude
higher than identical
targeting vectors delivered through transfection of naked DNA
In that year, Russell and Hirata from the University of Washington reported a surprising finding - when delivered via AAV infection, gene
targeting vectors with relatively short (1 kb) homology arms underwent homologous recombination
at a
frequency three orders of magnitude
higher than identical
targeting vectors delivered through transfection of naked DNA.
So, in its place of coaching them once per week
at the top of your leg day,
target them thrice per week by adding them into different coaching days with other body parts this is termed as
high frequency.
The needles are electrically stimulated
at two different
high frequencies, resulting in relaxation and analgesia of the
targeted muscles.