Sentences with phrase «target candidate genes»

The new knowledge and target candidate genes resulted from such unbiased study are ultimately important for researchers to understand the fundamental nature of stem cell proliferation and differentiation.»

A traditional way to target a candidate gene is to identify a molecule or process important to, say, emotion, and then go back and find the genes that control it.

Not exact matches

The finance chairman and a finance committee member of Gene Locke's mayoral campaign helped bankroll the conservative political action committee that sent out an anti-gay mailer targeting City Controller Annise Parker and other municipal candidates earlier this month, according to Texas Ethics Commission documents.

To generate a rich source of potential vaccine and drug target candidates, the team identified a set of genes that are more active in certain stages of the parasite life cycle and within the parasite's gut.

Starting with a candidate list of 20,000 genes, researchers screened down to eight before singling out VNN - 1 as the primary target.

We helped with the analysis of targeted 3730 sequencing of some candidate genes in a warfarin patient cohort, and uncovered another gene, (CALU, encoding calumenin) in which variants influenced warfarin dose.

Again, we can do this by selectively targeting RNAi (RNA interference) against candidate genes to specific neuron classes and testing the animal's performance in behavioral assays.

Being able to go back and forth between the mouse and human genomes so easily has also made it much simpler and quicker to target related human genes that could be candidates for drug development.

I look for genes, pathways, and candidate mutations associated with a disease, in order to understand the mechanism and the etiology of a disease, which may eventually lead to new therapeutic targets.

Of these, SLC24A4 and CACNA1H are potential candidate genes for BP regulation, and the latter is a drug target for a class of calcium channel blockers.

The approach to target validation utilizes RNAi, CRISPR, and ORF expression platforms to genetically perturb candidate target gene expression in relevant cancer cell lines, and then profile the resulting phenotypic changes with regard to their effect on various biochemical pathways.

Their contributions to the yeast community include physical mapping methods, synthetic lethality screen approaches for identifying cross-species candidate genes as potential cancer drug targets, and a widely used set of vectors and yeast host strains that have been instrumental in work that has led to countless discoveries in recent decades.

«With this technology, you can test the function of these candidate genes and measure what percentage of cells are generating into our target arterial cells,» says Zhang.

Avalanche has two drug candidates designed to treat the most common forms of color vision deficiency: AVA - 322 carries the gene for L - opsin and targets protan defects and AVA - 323 carries the gene for M - opsin and targets deutan defects.