As a monolayer of cells critical to photoreceptor function and survival, the RPE is an ideally accessible
target for cellular therapy.
Not exact matches
«Alcohol prevents ability to extinguish fearful memories in mice: Insight into
cellular mechanisms illuminates biological
target for PTSD
therapy.»
Wahl was on the tenure track in 2002 as a pathology researcher at Duke University, identifying
cellular targets for cancer
therapies, when funding dried up
for her research and she consequently failed to get tenure.
«It would be very difficult
for the virus to develop resistance against a
therapy that
targets a
cellular protein,» says Palese.
The
cellular processes that we have identified in this study as being important
for the development of stomach cancer provide new
targets for therapy that have not been explored before,» Dr. O'Reilly said.
The restriction of
cellular growth by p53 has been reported to result in cell cycle arrest or apoptosis [6], and
targeting p53 and restoring p53 function to limit tumor growth has been intensively researched
for cancer
therapy [7].
Targets of research range from basic molecular and
cellular mechanisms, the manipulation of these mechanisms in animal models, analyses of the genes and gene products in cardiovascular disease, and clinical research that seeks to improve diagnosis and
therapy for patients.