Sentences with phrase «target for disease»

Intestinal permeability — a new target for disease prevention and therapy.

10/29/2008 Eating Red Meat Sets Up Target for Disease - Causing Bacteria Non-human molecules absorbed by eating red meat increase risk of food poisoning in humans Offering another reason why eating red meat could be bad for you, an international research team, including University of California, San Diego School of Medic... More...

Measuring tau deposits using the novel radiotracer 18F - AV - 1451 (18F - T807), in conjunction with 11C - PiB to measure amyloid plaques and 18F - FDG to measure regional neurodegeneration, offers new insight into the neurodegenerative characteristics of Alzheimer's disease and shows that tau pathology may be an instrumental target for disease - modifying strategies.

Therefore, this could provide an important target for disease interventions or vaccine designs.

If it emerges that it is indeed a «catcher's mitt» for α - synuclein, it could provide a drug target for a disease whose 10 million sufferers are sorely in need of new medicines.

And I took the opposite half of the brain, pulled out the hippocampus, which is the area described by researchers as the target for disease, and ground it up, saving the RNA.

Research from Rutgers Cancer Institute of New Jersey shows that the RUNX2 protein, which regulates the transcription of genetic messages responsible for the different functions of cells, may play a role in melanoma cell growth and spread and could serve as a therapeutic target for the disease.

«A molecular atlas of calcific aortic valve disease: Study builds molecular networks of calcific aortic valve disease to identify key molecules and therapeutic targets for a disease that affects one in four older Americans.»

In addition to running his own lab, he directs the Applied Neurotherapeutic Research Group, a collaborative research initiative funded jointly by SFI and Wyeth, to understand the molecular underpinnings of changes in behavior and to identify new drug targets for diseases such as schizophrenia.

Now, Salk researchers have discovered how the molecule ERRγ gives this «healthier» brown fat its energy - expending identity, making those cells ready to warm you up when you step into the cold, and potentially offering a new therapeutic target for diseases related to obesity.

If additional work supports the finding, the study may provide researchers with potential new drug targets for the disease.

In order to find alternative targets for the disease, Guinovart and first author Giorgia Testoni of IRB Barcelona generated glycogenin - deficient mice, expecting to also block glycogen accumulation in cells.

Two - pore channels control Ebola virus host cell entry and are drug targets for disease treatment

«While we need to better understand how these abnormally regulated metabolites activate oncogenic proteins, our intriguing discovery suggests novel therapeutic targets for this disease,» says principal investigator and study leader Arnab Chakravarti, MD, chair and professor of Radiation Oncology and co-director of the Brain Tumor Program at the OSUCCC — James.

Scientists have eyed microRNAs as potential targets for disease - fighting treatments because their malfunction has been implicated in cancer, heart disease, viral infections, and other disorders.

An international study led by researchers at Monash University» Biomedicine Discovery Institute (BDI) has shone light on the way the Hepatitis C Virus (HCV) hijacks the communication systems in the host cells it infects, uncovering potential new therapeutic targets for the disease.

Leveraging this system could be a strategic therapeutic target for diseases like ALS and frontotemporal dementia.»

We investigate the role of genes and proteins in the onset of cancer, with the goal of identifying new treatment targets for this disease.

«This perspective will offer us a window into new therapeutic targets for these diseases.»

The study suggests a potential treatment target for diseases such as Crohn's disease and ulcerative colitis.

«We think this development will help other scientists better utilize open data, hopefully leading to the discovery of new therapeutic targets for disease,» says first author Andra Waagmeester, PhD, formerly a researcher at Maastricht University and now CEO of the start - up company Micelio.

Not exact matches

The technology's possibilities are staggering — in theory, allowing medical scientists to do everything from cure genetic disorders like sickle cell disease to identify gene targets for combating HIV.

Furthermore, an early - stage study pumping up the dose of its hemophilia A treatment — which aims to be a one - time therapy for the rare blood clotting - related disease — appeared to hit its targets without serious side effects.

Kevin Liang, a neuroscientist, explained to Soenksen that the brain is key to health, and so diseases that attack the brain offer a promising target for business and scientific innovators.

The bulk of research scientists working on Alzheimer's have long believed that a buildup of amyloid «plaques» is central to the disease's development — and that therefore targeting this protein is the best chance for a cure.

It is also restricted almost entirely to Africa, which, unfortunately for its victims, makes it a less attractive target for big drug companies than a host of non-fatal diseases (think erectile dysfunction) that are more common in rich countries.

LONDON, April 16 - Shire, the London - listed rare diseases specialist that is a potential takeover target for Japan's Takeda Pharmaceutical, is selling its oncology business to unlisted French drugmaker Servier for $ 2.4 billion.

That will then form a starting point for companies and researchers to develop precision medicines that can target these diseases and determine which patients may respond best to existing or new medicines, reported the Wall Street Journal.

Because, as Belmonte rightly explains, the new «precisely targeted» tools can help us «study species evolution, biology and disease, and may lead ultimately to the ability to grow human organs for transplant.»

Across the provinces and territories, vaccination rates for preventable diseases like influenza, pertussis (whooping cough) and pneumococcal (pneumonia) infections are well below national immunization uptake targets of around 80 percent.

Ionis Pharmaceuticals» mission is to develop safe and effective RNA - targeting drugs for both rare and more prevalent diseases and providing those drugs to the broadest group of patients as quickly as possible.

Cambridge, MA — March 30, 2017 — Aura Biosciences, a biotechnology company developing a new class of therapies to target and selectively destroy cancer cells using viral nanoparticle conjugates, announced today that it has enrolled and dosed the first patient in its Phase 1b clinical trial of light - activated AU - 011, an investigational, first - in - class targeted therapy in development for the treatment of ocular melanoma, a rare and life - threatening disease.

That therapy for treating melanoma is already in the development pipeline, along with 906 other biologics targeting over 100 diseases from autoimmune disorders to viruses.

What Stephen Hawking Missed: Small Biotechs Developing Promising Cell Therapies for Devastating Disease Source: Streetwise Reports (5/2/18) In the second of a two - part series exploring the disruptive cell therapy space, Maxim Group analyst Jason McCarthy takes a look at small - cap companies targeting big - ticket indications and their potential to drive blockbuster value for both patients and investors.

(Reuters)- Alnylam Pharmaceuticals Inc's RNAi - based drug that targets a rare genetic disease met the main goal of a key study, in a breakthrough for the new class of medicines that works by blocking disease - causing proteins.

Maastricht, The Netherlands, 1 November 2017 — Cristal Therapeutics, a clinical stage biopharmaceutical company developing targeted nanomedicines for the treatment of cancer and other diseases with high unmet patient need, announced today that it has begun a Phase 1b...

Preventive effects of drinking green tea on cancer and cardiovascular disease: epidemiological evidence for multiple targeting prevention

«Targeted promotion of the active SCFA producers as ecosystem service providers via personalised nutrition may present a novel ecological approach for manipulating the gut microbiota to manage T2DM and potentially other dysbiosis - related diseases,» Zhao added.

Traits targeted for improvement include higher nutritional quality; tolerance of pests, diseases, and environmental stresses, such as flood and drought; and reduced greenhouse gas emissions.

Smashing their campaign goal by raising twice as much as targeted, Souplantation and Sweet Tomatoes guests, team members, farmers and suppliers have raised $ 300,000 for the St. Jude Children's Research Hospital ® battle to help kids beat cancer and other serious diseases.

«The state needs to better understand asthma trends and better target publicly funded initiatives, particularly for Hispanic, African - American and the poorest New Yorkers struggling with this disease,» argued Comptroller DiNapoli.

Although Paladino has been targeted for removal since he told the arts newspaper that he wished then - President Barack Obama would die of mad cow disease and Michelle Obama would go live with a gorilla, the basis for the unusual proceedings is a petition filed by Board President Barbara Seals Nevergold and other board members accusing Paladino of disclosing confidential information discussed in closed - door sessions.

Carl Paladino has been targeted for removal since he told a Buffalo arts newspaper in December that he wished then - President Barack Obama would die of mad cow disease and Michelle Obama would go live with a gorilla.

«These new insights into the complexities of epigenetic regulation are contributing to our basic understanding of this process in human health and disease and gives us new vision for how to go about targeting errors in DNA methylation with innovative drug therapies.»

«Until recently we have been looking for individual genes associated with diseases, which drug companies then target with treatments.

Arman first worked to gain a thorough understanding of the medical conditions Eos was hoping to target, and then to identify the standard treatment strategies for those diseases.

«xIAP has other roles in the cell, such as regulation of cell death, so it is a tricky target for treating inflammatory diseases.

The m2R receptors therefore are a new potential target for treating the disease, Hart said.

«Searching for targeted treatments for inflammatory diseases.»

So it is very exciting to identify other potential targets for treating these diseases,» he said.