Sentences with phrase «target for treatment»
The findings, published in the journal Cell Reports, provide new insight into how melanoma grows and identifies a new target for treatment of melanoma and other cancers.
sciencedaily.com
The findings suggest a new mechanism for the body's control of fear and anxiety, and point to a new target for the treatment of anxiety disorders.
A protein produced by the immune system plays a critical role in the development of the disease and represents a novel potential target for treatment, new research suggests.
The findings could shake up prostate cancer research, providing targets for treatment of one of the most prevalent cancers in the west.
Identifying such factors is important in selecting the appropriate targets for treatment intervention in the context of sexual dysfunction and of improving women's sexual health and well - being.
Both define cell identity and are legitimate targets for treatment.
This promising finding may pinpoint those patients whose cancers are destined to return after surgery, but it also reveals a potential new target for treatment.
The findings could shake up prostate cancer research, providing targets for treatment, diagnosis and monitoring of one of the most prevalent cancers in the west.
A study published in Journal of Investigative Dermatology has identified a potential therapeutic target for the treatment of psoriasis, a chronic inflammatory disease of the skin that affects up to a 2 % of the population and which has still no cure.
«Scientists reveal potential new drug target for the treatment of rheumatoid arthritis.»
St. Jude researchers working with collaborators in China and Singapore have reported evidence that mutations in non-coding regions of the human genome contribute to leukemia in children and may offer promising targets for treatment in the future.
The new findings enhance scientific understanding of where infectious prion diseases might take hold in the brain and provide possible targets for treatment.
«We know that many genes are involved in ALS and a major goal in the field is to identify as many of these genes as we can so we can uncover targets for treatment at the cellular level,» says lead author Brittany Edens from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago.
«Understanding how these genes interact to contribute to the development of schizophrenia may allow us to identify the general pathway of the disease, potentially providing a better target for treatment.»
These lymphoid cells are thus an important target for the treatment of infection and chronic inflammation.
«In conclusion,» Nakano and fellow researchers wrote, «the FOXD1 - ALDH1A3 axis is critical for tumor initiation in mesenchymal GSCs, therefore providing possible new molecular targets for the treatment of GBM and other ALDH1 - activated cancers.»
The new insights will help scientists better understand the genetic origins of tumor metastases, and lead to more effective targets for treatment, said the researchers.
This finding demonstrated the unique contribution that self - efficacy plays in predicting treatment outcome and is concordant with previous findings that suggest that self - efficacy is a strong predictor of future behavior and that high levels of perceived self - efficacy may contribute to response to depression treatment, therefore justifying self - efficacy as a specific target for treatment intervention.
To acquire new insights into the biology and possible therapy of these tumors, Feigin et al. looked for aberrant expression of G protein — coupled receptors, cell signaling proteins that have been successfully targeted for treatment of other disorders such as depression.
«These results suggest that REV - ERB is a potent target for the treatment of DMD,» Burris said.
In addition, they conclude, «Our findings suggest that sleep problems may be an additional target for treatment and prevention strategies in female emerging adults with chronic pain and musculoskeletal pain.»
The study focused on the serotonin transporter, a molecule that regulates the amount of serotonin signaling between brain cells and is a major target for treatment of depression and mood disorders.
«Our findings indicate that APOE is not just involved in Alzheimer's risk and disease progression, but it could potentially be a real target for treatment or prevention.»
Today the brain's serotonin system is already a known target for the treatment of depression, and according to researchers it should be possible to use time signals in pharmaceutical development based on stem cells.
Our aim is to highlight the genetic networks that can impact on DM1 biomarkers to provide new therapeutic targets for treatments by chemical compounds.
«We are honored and pleased to be a recipient of this Grant Award, an integral part of our Bedside to Bench translation medicine strategy and its application to the identification of innovative targets for the treatment of cancer» said Christophe Quéva, CSO, iTeos Therapeutics.
These network maps are essential in pinpointing key regions in the brain that are affected in neurological disorders, and thus may be viable targets for treatment.
«The objective of our project is to evaluate the relevance of the transient receptor potential channel (TRP) TRPV1 as drug target for treatment of canine AD,» Torres added.
«Showing that TWEAK is a critical mediator in both conditions, makes it a potential therapeutic target for the treatment of inflammatory skin diseases in general.»
«Our work strongly supports that cancer stem cells are the main source of growth in these tumors and, as such, should be considered promising targets for treatment,» says Mario Suvà, MD, PhD, of the MGH Department of Pathology, co-senior author of the Nature paper.
«Therefore, it is important to consider this receptor subtype as potential target for the treatment of psychiatric illnesses characterized by alterations in personal relevance attribution.»
In regards to the proposed medicinal «cure for love» (15 February, p 26), one possible target for treatment would be...
«By greatly narrowing the specific genes involved in social disorders, our findings will help uncover targets for treatment and provide measures by which these and other treatments are successful in alleviating the desperation of autism, anxiety and other disorders,» says Korenberg.
Rahel hopes «that future work in this area of research will lead to more accurate diagnoses and better targets for treatments.»
«It raises the possibility that nicotinic receptors may be important targets for the treatment of multiple addictions, not just nicotine.
This study provides new candidate molecular targets for the treatment of such lymphomas.
These GABA neurons may represent a promising new target for treatment of cannabis use disorder, a common condition on the rise in the United States.
Researchers at the La Jolla Institute for Allergy and Immunology, in collaboration with colleagues the University of California, San Diego, identified a novel drug target for the treatment of rheumatoid arthritis that focuses on the cells that are directly responsible for the cartilage damage in affected joints.
Advances in our understanding of the biological pathways and mechanisms involved will help uncover new targets for treatment, which could one day translate into better, more personalised care for people living with schizophrenia.»
These relatively normal tissue cells communicate with the cancer cells and play a major role in cancer progression, and could offer a new target for treatment.
The depressed cortisol response concurs with the known effects of loneliness and provides a potential target for treatment.
«Genetic screening of brain metastases could reveal new targets for treatment.»
«Serotonin receptor is involved in eczema and other itch conditions: Research points to new target for treatments.»
In their work, Cohen and Brady engineered gut bacteria to produce specific ligands, N - acyl amides, that bind with a specific human receptor, GPR 119, that is known to be involved in the regulation of glucose and appetite, and has previously been a therapeutic target for the treatment of diabetes and obesity.
Our studies reveal that AHR is a novel target for treatment of this disease and potentially other diseases that manifest with excessive scarring,» explained lead investigator Richard P. Phipps, PhD, of the Department of Environmental Medicine and Flaum Eye Institute of the School of Medicine and Dentistry of the University of Rochester (Rochester, New York).
The research, which involved more than 12,000 older women, found that screening through GP practices allowed patients to be targeted for treatment.
A better understanding of the function of neuromodulators, such as COX - 2 and TIA - 1, may help identify novel therapeutic targets for the treatment of epilepsy.»
The team has shown that the microenvironment that controls hematopoietic stem cells can be targeted for the treatment of a set of disorders called myeloproliferative neoplasias, the most prominent of which are chronic myelomonocytic leukemia (CMML), juvenile myelomonocytic leukemia (JMML), and atypical chronic myelogenous leukemia (CML).