Sentences with phrase «target genes responsible»

In doing so, they will be guided by one central question: how might a drug - based treatment target the gene responsible for the release of fatty acids and the enzyme ATGL, and how might it do so exclusively in adipose tissue?

Now, the team has found that another type of dwarf phage also targets a gene responsible for a cell wall - building enzyme.

Not exact matches

If we know which genes are responsible for breast cancer, then we can tailor therapies to target those genes specifically.»

To validate their findings, the scientists injected the novel nanoparticles into pancreatic tumor - bearing mice and observed that by balancing these two targets — bringing them to a normal level by increasing their expression or blocking the gene responsible for their expression — they significantly prolonged the survival of the mice.

Still, the standard form of liver - targeted gene therapy carries a range of potential complications, including the risk of harmful mutations and of the body mounting an immune response against the viral vectors used to carry the correct forms of the defective genes responsible for haemophilia.

«We are currently identifying the genes responsible for generating the DNA tether, which could be promising novel targets for the next generation of cancer therapies.»

Utilizing genetic approaches such as «fine mapping» and «genome editing,» the researchers narrowed the region of the chromosome and targeted each gene to responsible for affecting the behavioral response to the drug.

Vaxwave ® is based on lymphocytic choriomeningitis virus (LCMV) and in this vector the gene encoding the LCMV envelope protein, normally responsible for virus entry into target cells, has been deleted and replaced with a target gene of interest.

«Using a clinically tested gene therapy platform, we are able to induce very specific regulatory cells that target the self - reactive cells that are responsible for causing multiple sclerosis,» says Brad E. Hoffman, co-author of the study.

Published in Science, an exciting paper describes a new CRISPR - based gene editing system that targets RNA, the molecule responsible for translating DNA into protein, instead of DNA.

We hypothesized that antimicrobial resistance can be reversed by targeting chromosomal non-essential genes that are not responsible for acquired resistance but essential for resistant bacteria under therapeutic concentrations of antimicrobials.

The drug, named Inclisiran, utilizes a technique called RNA interference therapy which targets, and switches off, a specific gene known to be responsible for elevated LDL levels.