«What was really interesting is that the microRNAs specifically
target host genes that are involved in the plant's defense against the parasite.»
Not exact matches
«So, with this knowledge, the dream is that we could eventually use
gene editing technology to edit the microRNA
target sites in the
host plants, preventing the microRNAs from binding and silencing these
genes.
They then measured the amount of messenger RNA of
genes that were
targeted by the dodder microRNAs and saw that the level of messenger RNA from the
host was reduced when the dodder microRNAs were present.
More importantly, once inside the
host, the food - derived exogenous miRNAs can regulate
host physiology by regulating
host «
target»
genes in the cross-kingdom manner.
Instead VIP provides the protective antibody
gene, giving the
host the tools to
target the malaria parasite.
Their contributions to the yeast community include physical mapping methods, synthetic lethality screen approaches for identifying cross-species candidate
genes as potential cancer drug
targets, and a widely used set of vectors and yeast
host strains that have been instrumental in work that has led to countless discoveries in recent decades.
He has made several important contributions in this area including identifying a new strain of CHIKV virus, identification of
host cellular
targets of HIV accessory
genes, new novel DNA vaccine approaches for HIV, CHIKV, RSV, Dengue, MERS and Zika among others.