Sentences with phrase «target hypoxic»

Embryonic endothelial progenitor cells armed with a suicide gene target hypoxic lung metastases after intravenous delivery.

However, in order to come close to achieving a reduced target hypoxic zone of 5,000 square kilometers (1930.5 square miles) by 2050, nitrogen levels would have to be brought to zero — a scenario that the researchers note in their paper is «not only considered unrealistic, but also inherently unsustainable.»

ERK1 / 2 inhibition increases antiestrogen treatment efficacy by interfering with hypoxia - induced downregulation of ERalpha: a combination therapy potentially targeting hypoxic and dormant tumor cells

Not exact matches

Van Meter and her colleagues sought to explore what future targets might be necessary to reduce the hypoxic zone.

Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin - 2.

Confirmation of hypoxic conditions was carried out using immunohistochemistry to measure expression of HIF - 1α and qRT - PCR to assess upregulation of target genes at the RNA level (Supplementary Fig.

Importantly, NSCs can target breast cancer metastasis in the brain [9] and can penetrate deep and hypoxic regions of solid tumors [7].

[6] Another natural isoflavinoid, 4 - O - methyl alpinumisoflavone, isolated from the tropical rainforest tree, Lonchocarpus glabrescens, could inhibit HIF - 1 activation and hypoxic induction of HIF - 1 target genes (CDKN1A, GLUT - 1, and vascular endothelial growth factor (VEGF)-RRB-.