That's it; you don't have tens or hundreds to choose from if achieving the recommended scientific
target of the leading scientists is your goal.
Not exact matches
«The goal
of the BCS was to understand better the distribution and conservation needs
of Bornean cats and small carnivores and subsequently, to enable
targeted conservation efforts to those carnivores which are most threatened,» said Dr. Andreas Wilting,
scientist at the IZW and
lead editor
of this supplement.
In a study published in the April issue
of the Journal
of Neuroscience, Saint Louis University
scientists led by professor
of pharmacological and physiological sciences Daniela Salvemini, Ph.D., discovered that drugs
targeting the A3 adenosine receptor can «turn off» pain signals in the spinal cord to provide relief from chronic pain.
«The worst thing would have been no replacement
target,» says planetary
scientist Donald Brownlee
of the University
of Washington, Seattle, who
leads the Stardust mission en route to gather dust during a flyby
of Comet Wild 2.
Dr. David Fredricks, a physician -
scientist at Fred Hutchinson Cancer Research Center and senior author
of the study, said the results could
lead to a better understanding
of how biological conditions may promote infection by the virus that causes AIDS, and perhaps offer
targets for future prevention research.
Using experimental models and state -
of - the - art technology, the
scientists found that switching off this protein
leads to better control
of glucose production from the liver, revealing a potential new
target that may be used to treat type 2 diabetes and other metabolic diseases.
The new insights will help
scientists better understand the genetic origins
of tumor metastases, and
lead to more effective
targets for treatment, said the researchers.
A team
of researchers
led by UC San Francisco
scientists has identified a new drug
target for triple - negative breast cancer, an aggressive disease subtype that has the poorest outcomes and accounts for as many as one in five cases.
I think most
scientists expect that the way Bt crops are being deployed will eventually
lead to the evolution
of resistance in the
target pests, which means that the Bt cotton won't work anymore.
An experimental drug that
targets abnormally high levels
of a protein linked to cancer growth appears to significantly reduce the proliferation
of prostate cancer cells in laboratory cell cultures and animals, while also making these cells considerably more vulnerable to radiation, according to results
of a study
led by Johns Hopkins
scientists.
In tests on zebrafish, flies and mice,
scientists found that treating the disease with purified quercetin — which
targets beta - catenin —
led to a significant improvement in the health
of nerve and muscle cells.
Led by Massey's Deputy Director Steven Grossman, M.D., Ph.D., a team
of scientists targeted the gene CtBP with a drug known as HIPP (2 - hydroxy - imino phenylpyruvic acid) and were able to reduce the development
of pre-cancerous polyps by half and return a normal lifespan to mice born with a predisposition to intestinal polyps.
«Despite substantial public health efforts, flu vaccine rates for U.S. children are well below national
targets,» says
lead author Sarah J. Clark, M.P.H., associate director
of the University
of Michigan C.S. Mott Children's Hospital National Poll on Children's Health and associate research
scientist in the U-M Department
of Pediatrics.
The studies present the first genetic evidence
of a link between cholesterol and the disease, and they may
lead scientists to identify new
targets for therapy.
After identifying three different types
of resistance to a promising investigational lung cancer drug in a phase 1 trial, a team
of researchers
led by Dana - Farber Cancer Institute
scientists say new
targeted inhibitors and combinations are urgently needed to stay ahead
of tumors» constant and varied molecular shape - shifting.
Research
led by
scientists at the University
of Birmingham shows more precisely how G protein - coupled receptors, which are the key
target of a large number
of drugs, work.
A team
of scientists led by Gladstone's Dr. Steven Finkbeiner have identified a cellular mechanism that can be
targeted to treat amyotrophic lateral sclerosis (ALS).
A team
of researchers
led by Caltech
scientists has shown that nanoparticles can function to
target tumors while avoiding adjacent healthy tissue in human cancer patients.
Scientists at the University
of York have identified a therapeutic
target which could
lead to the development
of new treatments for specific blood cancers.
LA JOLLA —
Scientists at the Salk Institute for Biological Studies have identified a key genetic switch linked to the development, progression and outcome
of cancer, a finding that may
lead to new
targets for cancer therapies.
«Phenotypic screens are probably underutilized for identifying drug
targets and potential compounds,» says Daniel Tardiff, a
scientist in the Lindquist lab and
lead author
of one
of the Science papers.
2013 — Our
scientists unravel complex chains
of events that
lead to skin cancer becoming resistant to drugs that
target BRAF, and are the first to show that a new combination
of drugs is more effective at slowing cancer's growth.
«We think this development will help other
scientists better utilize open data, hopefully
leading to the discovery
of new therapeutic
targets for disease,» says first author Andra Waagmeester, PhD, formerly a researcher at Maastricht University and now CEO
of the start - up company Micelio.
PULLMAN, Wash. —
Scientists at Washington State University have identified a crucial step in DNA repair that could
lead to
targeted gene therapy for hereditary diseases such as «children
of the moon» and a common form
of colon cancer.
Convinced by ambitious
scientist Bolivar Trask (Peter Dinklage) that the solution to the problem is to green - light a line
of mutant -
targeting drones called Sentinels, Tricky Dick acts with predictably self - serving expediency — and inadvertently triggers a series
of events that
leads to a dystopian future in which humans and mutants alike teeter on the verge
of extinction.
According to Climate Progress, the report, Climate Policy and Industrial Competitiveness (pdf), completed by the economists, climate
scientists, and academics
of the German Marshall Fund, reveals that Europe's cap and trade has
lead many countries in the EU to meet their carbon
targets as agreed to in the Kyoto Protocol.
«Australia's
leading climate change
scientists are being
targeted by a vicious, unrelenting email campaign that has resulted in police investigations
of death threats,» the Canberra Times reports.
Lobby groups funded by the US oil industry are
targeting Britain in a bid to play down the threat
of climate change and derail action to cut greenhouse gas emissions,
leading scientists have warned.
Australia's
leading climate change
scientists are being
targeted by a vicious, unrelenting email campaign that has resulted in police investigations
of death threats.
To stay within the temperature
target / ceiling
of ~ 1 C that
leading climate
scientists recommend, we have run out
of carbon budget, and have accumulated significant carbon debt.