Sentences with phrase «target regulatory sequence»

The authors designed an electromobility shift assay (EMSA) to examine how the missense substitution affected PAX7 «s ability to bind a target regulatory sequence.

Not exact matches

Although each type of TF preferentially binds certain regulatory DNA sequences, evidence shows that this binding specificity is limited, and that TFs bind other noncognate targets, too.

Molecular studies of Hox - regulated target genes suggest that these changes occur through accumulation of mutations in regulatory DNA sequences.

But rather than changes in doublesex itself, these studies revealed changes in downstream targets of dsx, via changes to specific DNA sequences to which DSX protein binds in the cis - regulatory regions of the bric - a-brac and desatF genes and affecting sex differences in abdominal pigmentation and pheromone production.

At present we are engineering regulatory sequences to direct gene expression selectively to target cells and tissues in the CanEuCre / Pleiades Promoter Project.