Sentences with phrase «target tissues and organs»

Therapy using live cells is increasingly used to replace damaged tissue, deliver gene therapies to target tissues and organs, and stimulate self - healing along with a number of other applications.

«As an oral agent that targets all tissues and organs in the body, RG7916 has the potential to impact all aspects of the disease.

Not exact matches

«We've previously understood very little about how these bacteria move through and into our organs, tissues, and central nervous system, but our work sheds light on these processes and could form the basis for novel therapeutics that target the bacterium's ability to invade.»

Rutgers engineers have invented a «4D printing» method for a smart gel that could lead to the development of «living» structures in human organs and tissues, soft robots and targeted drug delivery.

These «nanoswimmers» cross the blood — brain barrier highly efficiently, and could lead to the development of drug delivery systems that navigate through tissues and organs to target specific sites precisely.

Reactivation of HBV may occur with chemotherapy, organ and tissue transplantation, High dose corticosteroids, and biologicals targeting tumor necrosis factor - alpha (TNF - α), Anti-TNF medications are used in treating rheumatic diseases, such as rheumatoid arthritis, digestive conditions that include Crohn's and colitis, and dermatologic conditions, such as psoriasis.

Contrast agents that exert a strong effect are said to have high «relaxivity,» which enhances the visual contrast between the target organ and surrounding tissue.

Tissues being sampled include biopsy material from target organs, peripheral blood cells and serum / plasma, germline DNA, and stool for microbiota analysis.

«Biological systems are soft, and if you want to design a device that can target those tissues or organs, you should match their mechanical interface as well,» Tian said.

Ideally, the researchers found that the best targets were genes or proteins primarily expressed in one specific tissue, so the drug treats the disease at its core, without interfering with other, healthy tissues or organs, and thus causes fewer side - effects.

Therefore the group studies with sophisticated imaging technology in vitro and ex vivo: i) the molecular mechanism driving the migration of HIV through the intestinal epithelial barrier; ii) the cellular targets in the mucosa, in specific macrophages and DCs, to identify the possible pathways to invade the tissue and disseminate to other organs; iii) the involvement of DCs and their functional properties in mediating adaptive immune responses at mucosal level; and iv) the role of antibodies with different effector functions in changing the pathways of the virus.

These syndromes include conditions in which autoimmunity is clearly implicated as causal, in light of identification of autoantibodies to relevant autoantigens; diseases suspected to be autoimmune because of the presence of autoantibodies, although the autoreactive response has not been proven to be pathogenic and could be a consequence or marker of tissue damage; and other diseases often considered to be «autoimmune,» such as psoriasis or inflammatory bowel disease, characterized by organ - targeted inflammation but without evidence of a stimulating autoantigen.

Transplanted organs, tissues and cells are targets of the host immune response, that, in the absence of adequate immunesuppression, lead to graft loss.

Thus, tissue clearing allows researchers to more quickly screen the viral vectors for those that best target the cells and organs of interest.

The Metabolomics & Proteomics Technology Unit will offer localizomics approaches based on MS Imaging on tissue / organs slices (or on in - vitro cell cultures), either in targeted MS (i.e. drug and metabolites distribution) or in untargeted high resolution (HR) MS (metabolite profiling).

LA JOLLA — Salk Institute researchers have discovered a holy grail of gene editing — the ability to, for the first time, insert DNA at a target location into the non-dividing cells that make up the majority of adult organs and tissues.

gentle non-invasive form of therapy that targets the organs and their surrounding tissues including ligaments, fascia and membranes.

Almost all organs and tissues can be targeted by an autoimmune disease.

The overall goal of IV Nutritional Therapy is to achieve blood plasma nutrient concentrations not obtainable by oral supplement administration to achieve health optimization and to directly target diseased or nutritionally deficient cells / organs / tissues of the body.

However, when a person has an autoimmune disease, the immune system mistakenly turns on itself, targeting cells, tissues and organs of your own body.

The campaign to promote organ, tissue and eye donation and transplantation, which was launched by Indianan Donor Network in 2016, will target IMSA fans to become donors in honor of the late Justin Wilson and Bryan Clauson.

Eventually, studies done using dye showed that enzymes, hormones, peptides and proteins in fact are absorbed intact and are able to target specific tissues and organs.

The viral infection mostly targets the respiratory and gastrointestinal tracts of dogs, although there is an increasing incidence of canine distemper that invades the brain and spinal cord as well as other organs and tissues of the body such as optic nerves, urogenital structures, and epithelial tissues.