Sentences with phrase «targeted cell metabolism»

Not exact matches

Yang said the study not only indicated which genes are affected by traumatic brain injury and linked to serious disease, but also might point to the genes that govern metabolism, cell communication and inflammation — which might make them the best targets for new treatments for brain disorders.

For instance, researchers used virtual screening to identify compounds that target the gene for PFKFB3, an enzyme that helps regulate the metabolism of cancer cells.

«Cancer cell metabolism kills: Possible new therapies targeting energy supply of cancer cells?.»

The findings may help to explain how cancer cells maintain their high levels of metabolism — and could uncover future targets for cancer treatment.

Understanding these pathways, and the identification of the key proteins that control the ability of cancer cells to reprogram their metabolism through biochemical, and epigenetic or genetic alterations that make them resistant to therapies, is of paramount importance for the design of more targeted and therefore less toxic therapies.

A Legionella effector acquired from protozoa is involved in sphingolipids metabolism and is targeted to the host cell mitochondria.

Advances in research into the immunological evasion, metabolism and latency of metastatic cancer cells allow the identification of potential targets to test therapies.

Unlike the case of most gene therapies that are intended to permanently alter their target cells, however, Oisín's senoablative genetic constructs will not be inserted permanently into the patient's genome: instead, its genetic payload will be expressed temporarily from the main body of the cell, following which the construct will be passively degraded by normal cellular metabolism.

Jared Mayers (Brigham and Women's Hospital Boston, USA), winner of the prize category Translational Medicine, kicked the event off with his research on differences in how cancer cells and normal cells utilize of nutrients and how this has been linked to genetic changes in cancer, opening up an opportunity for drugs targeting metabolism.

The drug works by increasing the natural metabolism of the body while targeting fat cells for energy burning use while saving important muscle fibers.