The team used a designer drug technology known as DREADD to selectively turn off
targeted glial cells, something that has not been done before, said Grace.
Therefore, it stands to reason
that targeting these glial cells (in lieu of or in combination with neurons) may dramatically improve current treatments.»
Not exact matches
The virus appears to invade the brain by infecting a type of
glial cell called olfactory ensheathing
cells (OECs), which nourish smell - sensing neurons and guide them from the olfactory bulb to their
targets in the nervous system.
Targeting HO - 1 is therefore another potential approach to improving photodynamic detection in human
glial cell cancers.
However, research published in Nature Biomedical Engineering reveals that it may also be important to
target the supportive
glial cells surrounding the neurons.
The brain
cells targeted are called «
glial»
cells - not «neurons», which are the brain
cells that send messages to each other.
Understanding the role of
glial cells in glaucoma as well as what happens to the optic nerve where the retinal nerve axons leave the eye may present new therapeutic
targets and even potential biomarkers of glaucoma.
Avigen discovered the utility of AV411 through its internal program to develop innovative and
targeted approaches to reducing nervous system dysfunction caused by
glial cell activation.