Sentences with phrase «targeted nucleic»

«Our research supports the development of targeted nucleic acid delivery platforms for therapeutics for autoimmune diseases and cancer,» says Prof. Peer.

The Unit's scientific mission covers the design, synthesis, molecular modeling, as well as biophysical, biochemical and cellular studies of small - molecule probes and drug candidates targeting nucleic acids or proteins involved in cancer.

Not exact matches

The exterior of the nanoparticle is coated with nucleic acids that act as targeting agents, drawing the delivery system to the retina and facilitating uptake by RPE cells.

Together with his principal investigator (PI), he had realized the commercial potential of modifying nanoparticles with nucleic acids to create targeted, personalized medicines for a myriad of diseases.

It asserted that bacterial death probably results from chlorine attacking a variety of bacterial molecules or targets, including enzymes, nucleic acids and membrane lipids.

They can also deliver precise doses of drugs, nucleic acids, or proteins to targeted points on the cell.

The two cell types are important to a broad range of organ systems in the body and play active roles in diseases that could be targets for nucleic acid therapies.

BioGene Limited are based near Cambridge and provide a «solution - based» portfolio of products, services and support — to encompass the key application areas of molecular biology to include Nucleic Acid Purification, Target Amplification and Post-Amplification Analyses.

«By selectively targeting the source of the immune activation rather than shutting off the innate immune system downstream, these nucleic acid scavengers are able to limit pathological inflammation without compromising one's ability to fight a viral infection,» Sullenger said.

Scientists are also breaking ground with nucleic acid platforms that have the potential to deliver cancer vaccines, for neoantigens and other targets.

Intrigued by the ability of certain polymers to mop up DNA and RNA for gene transfer, Sullenger and colleagues tested the idea that these chemical compounds might also be effective targeting such nucleic acids as they arise in cell death.

Special computational techniques are also available to discover biological targets (proteins, nucleic acids) of a drug.

In this case, both the target and the candidate drug are nucleic acids.

A University of Colorado Cancer Center study recently published in the top - ranked journal Nucleic Acids Research (NAR) describes a database named multiMiR, the most comprehensive database collecting information about microRNAs and their targets.

Antisense inhibitors are synthetic nucleic acid drugs that can be designed to selectively bind to messenger RNA from the targeted, disease - linked gene, and inactivate it.

Target information above from: UniProt accession P46013 The UniProt Consortium The Universal Protein Resource (UniProt) in 2010 Nucleic Acids Res.

Target information above from: UniProt accession Q9UBK2 The UniProt Consortium The Universal Protein Resource (UniProt) in 2010 Nucleic Acids Res.

His current research focuses on chemical evolution of sequence - defined carriers for drugs, proteins and therapeutic nucleic acids, with a medical focus on tumor - targeted therapies.

Our group seeks to investigate the use of chemically - modified nucleic acid aptamers, single stranded DNA or RNA sequences that specifically bind to a diverse variety of targets, in biosensing and catalysis.

Dr. Maria DeRosa's research examines a type of nucleic acid called «aptamers» that can fold into 3D nanoscale shapes capable of binding tightly to a specific molecular target.

Enzon's drug - development programs utilize two platforms: Customized PEGylation Linker Technology (Customized Linker Technology ®) and third - generation mRNA - targeting agents utilizing the Locked Nucleic Acid (LNA) technology.