Sentences with phrase «targeted therapies for»
Grant 1557: High - Resolution Cytogenetic Analysis of Histiocytic Malignancies and Development of a Targeted Assay to Screen for Expression Level Changes Dr. Matthew Breen, PhD Project Goal: The goal of this project is to narrow down the search for genes playing a key role in Histiocytic Malignancies and thus move a step closer to developing targeted therapies for canine patients diagnosed with this devastating cancer.
https://cvm.ncsu.edu/
Endocyte, Inc. is a biopharmaceutical company, which develops targeted therapies for the treatment of cancer and inflammatory diseases.
You will walk away with a solid understanding of how to identify and address neurological imbalances, and be able to implement targeted therapies for yourself, your family, clients and / or patients.
You will walk away with a solid understanding of how to intelligently balance hormones, and be able to implement targeted therapies for yourself, your family, clients and / or patients.
No matter what your background, you will walk away with a solid understanding of the inner - workings of the digestive tract, and be able to implement targeted therapies for restoring digestive health for yourself, your family, clients and / or patients.
National Cancer Institute and ECOG - ACRIN announce the July 2015 opening of the NCI - MATCH / EAY131 trial, a multi-arm phase II precision medicine study that seeks to determine whether targeted therapies for people whose tumors have specific gene mutations will be effective regardless of cancer type.
«We hope that this research can contribute to similar breakthroughs in targeted therapies for pancreatic ductal adenocarcinoma,» said Baines.
«This offers the opportunity for development of epigenetic targeted therapies for patients with ALL that could be broadly applicable to many patients.»
With the currently approved FDA cancer therapeutics drugs, we are only targeting the tip of the iceberg (85 targeted therapies for 105 gene products (1)-RRB- and with over 22,000 genes in our genome many genes are being neglected!
The study, published as the cover story of Cell Reports, provides a singular look into the genetic and non-genetic causes of Parkinson» s disease, which will help lead to more effective, targeted therapies for patients facing this devastating disease.
Results of the study, published today (19 March) in Nature Genetics, could open the door to new targeted therapies for this debilitating disease in the future.
The last few years have seen a tremendous level of discovery, with innovative, targeted therapies for leukemia and other blood cancers resulting in dramatic and sustained remissions.
«The truly interesting point will be to assess the clinical benefit of C3 - targeted therapies for PNH patients, and we are therefore looking forward to the upcoming clinical trials of novel complement inhibitors,» Ricklin notes.
Can implantable technology help deliver targeted therapies for brain cancer?
There, in a quest to develop targeted therapies for ovarian cancer, she began studying necroptosis, a form of programmed cell death.
The findings illustrate the potential relevance of considering adaptive responses by tumor cells when designing targeted therapies for cancer.
Identifying the origin could lead to targeted therapies for these very common diseases.»
In the era of personalized cancer therapy, patients with TNBC remain at considerably higher risk of relapse and death than patients with other breast cancer subtypes, due to the aggressive nature of TNBC and the lack of newer targeted therapies for the disease.
Dr. Cole's research interests include cancer genomics and the identification of molecularly targeted therapies for pediatric malignancies.
«Research finding could lead to targeted therapies for inflammatory bowel diseases.»
Professor Jean - Charles Soria, Chairman of the Drug Development Department at Gustave Roussy Cancer campus, France, will tell the Symposium: «Currently, there are no approved targeted therapies for mutant EGFR lung cancer patients who develop the T790M mutation, which means their disease inevitably will get worse.
Understanding this process can lead to better targeted therapies for pancreatic cancer.
«Understanding how the invading Ebola virus impacts the host's immune system is a very important step in developing targeted therapies for Ebola virus disease,» said Bukreyev.
«We desperately need better, more targeted therapies for both types of bladder cancer.»
«This research could help us find biomarkers for early detection, as well as provide information for developing targeted therapies for this devastating disease.»
The findings, which were published online in the journal Cancer Cell, could ultimately lead to new targeted therapies for many other types of cancer carrying similar p53 mutations.
«We are excited that our translational research team of clinicians and basic researchers have come together to present these novel findings and hope that future studies and trials based on this work can move forward to bring targeted therapies for TED,» commented Dr. Phipps.
«New targeted therapy schedule could keep melanoma at bay: Optimizing the timing of targeted therapies for melanoma reverses tumor growth, and resistance can be mitigated..»
«Genes may cause tumor aggressiveness, drug resistance in African - American prostate cancer: Research found many targeted therapies for prostate cancer may not be effective against tumors in African - American men.»
Currently, there are no targeted therapies for affected children, who are usually treated with topical steroids and, in severe disease, with immunosuppressant drugs.
«Our findings offer new directions for targeted therapies for children with eczema,» says Amy Paller, MD, co-senior author and dermatologist at Ann & Robert H. Lurie Children's Hospital of Chicago, as well as Chair of Dermatology and Professor of Pediatrics at Northwestern University Feinberg School of Medicine.
«These are optimistic results for one of the first targeted therapies for cancer stem cells,» says Antonio Jimeno, MD, PhD, investigator at the CU Cancer Center, director of the university's Cancer Stem Cell - Directed Clinical Trials Program, and principal investigator of the clinical trial at the CU Cancer Center site.
Incyte's (NASDAQ: INCY) Jakafi racked up $ 1.1 billion in sales last year as the only targeted therapy for patients with myelofibrosis, but a majority of patients who take it eventually relapse.
«These new drugs are opening the door for more avenues of targeted therapy for the future,» says American Cancer Society president Ralph Vance, a professor of medicine at the University of Mississippi School of Medicine.
«This study forms the basis for future research in patients with breast cancer and offers hope for targeted therapy for patients with aggressive triple - negative inflammatory breast cancer,» said lead researcher Mateusz Opyrchal, M.D., Ph.D., Assistant Professor of Oncology at RPCI.
«Identifying NTM as one of the triggers will hopefully provide a clue to the future development of a targeted therapy for these patients,» he added.
«Previous bacterial infection increases risk of newly - diagnosed Sjögren's syndrome: Identifying trigger will hopefully help future development of targeted therapy for patients suffering from this debilitating disease.»
This pathway is currently the focus of development of targeted therapy for moderate - to - severe eczema, suggesting that these same agents being tested in adults could also be useful in young children.
«This provides a rationale for a potential targeted therapy for this specific subtype of JMML,» said Weiss.
«Potential targeted therapy for lung cancer identified using fly model.»
«Thanks to a deeper understanding of cancer biology, we have a potential new targeted therapy for multiple myeloma, and can better tailor treatment for kids with Wilms tumor.
Unraveling the underlying mechanism could help pave the way toward making phages a targeted therapy for diseases like cholera.
These findings, published in Human Molecular Genetics, point to new possibilities for targeted therapy for SMA.
Targeted therapy for genetic mutations is much more effective.
This project will address this question and then utilize this knowledge to develop a targeted therapy for AMD.
New research findings from The University of Texas at Dallas unveil how kidneys filter ultra-small engineered particles, which may lead to new ways of developing targeted therapy for the detection and treatment of kidney...
MD Anderson and BridgeBio Pharma launch Navire Pharma to develop targeted therapy for patients with difficult - to - treat cancer
Targeted therapy for this disease is difficult because we still do not have a firm understanding of what causes it.
Not exact matches
Gene therapy, for example, frequently involves using a virus to deliver a gene to the cells that scientists are targeting.
I won't reveal yet who my favorites are, but I will say that these young scientist - founders came up with very creative solutions for preventing infections in some common surgeries, tackling resistance in targeted antibody drugs, improving gene vectors for cell therapies, helping the vision - impaired «see» faces and better read their environments, imaging hard - to - see spots in the lungs and other organs, improving genetic risk analysis, and expediting the logistical operations of hospitals.