Sentences with phrase «targeting disease states»

Not exact matches

«The state needs to better understand asthma trends and better target publicly funded initiatives, particularly for Hispanic, African - American and the poorest New Yorkers struggling with this disease,» argued Comptroller DiNapoli.

The Donald J. Trump Foundation gave away $ 158,250 in 2014 to fight cancer and other diseases, many of which target children, and donated $ 141,000 to groups that promote conservative social policy he would espouse in his presidential campaign a year later, state and federal records show.

«The state of the art right now is targeting two or three genes simultaneously and then looking at the effects, but we think that perhaps the gene sets that need to be modulated to address some of these diseases are actually broader than that,» says Lu, who is the senior author of the study.

«Our findings suggest that PRMT5 is a possible prognostic factor and therapeutic target for glioblastoma, and they provide a rationale for developing agents that target PRMT5 in this deadly disease,» says co-corresponding author Robert A. Baiocchi, MD, PhD, associate professor of medicine and a hematologist at the OSUCCC — James who is also collaborating on an Ohio State effort to develop a PMRT5 inhibitor.

Using virtual tissue technology, researchers at Indiana University have identified a potential new drug target in the fight against polycystic kidney disease, an illness with no effective FDA - approved treatment that affects 200,000 people per year in the United States.

Ben Stanger, MD, PhD, a professor in the division of Gastroenterology, and first author Ravi Maddipati, MD, an instructor in the division of Gastroenterology, say that these results may prove useful in designing better targeted therapies to stop tumor progression and provide an improved non-invasive method for detecting early disease states in this highly lethal cancer.

Using experimental models and state - of - the - art technology, the scientists found that switching off this protein leads to better control of glucose production from the liver, revealing a potential new target that may be used to treat type 2 diabetes and other metabolic diseases.

Monitoring immune responses by measuring cytokine levels has become an integral part of disease - related research, providing clues to the state of the immune system and how it could be targeted therapeutically.

So they are a potential target for new therapies for the disease which is incurable according to the present state of research.

The WHO, the Centers for Disease Control and Prevention (CDC), and professional societies have recommended targeted testing and treatment of high - risk individuals with latent TB infection as part of an effort to eliminate TB in the United States.

We use a combination of genomics, systems biology, biochemistry, bioinformatics and molecular biology to investigate the networks formed by RNA binding proteins, miRNAs and their target genes and evaluate their impact on biological processes, cancer and disease states.

«With emphasis on reaching a targeted low - disease activity state, physicians have many drugs to choose from for treating RA patients including triple therapy.

«Usually that's useless because they are already inactive in that state, but this finding suggests we might be able to find new therapeutic approaches to target these diseases.»

ALFA compiles the current state - of - art about the annotations of DNA regulatory elements (such as transcription factor binding sites, microRNA target sites) for a better understanding of biological processes underlying rare diseases.

Biochemical sleuthing by an Indiana University graduate student has ended a nearly 50 - year - old search to find a megamolecule in bacterial cell walls commonly used as a target for antibiotics, but whose presence had never been identified in the bacterium responsible for the most commonly reported sexually transmitted disease in the United States.

These off - target effects may actually be beneficial in treating IBD, primary sclerosing cholangitis, primary sclerosing cholangitis / IBD - related CRC, and asthma, whereby a multitude of abnormal signaling involving inflammation, oxidative damage, DNA damage, and apoptotic abnormalities exists to manifest itself into a diseased state.

PULLMAN, Wash. — Scientists at Washington State University have identified a crucial step in DNA repair that could lead to targeted gene therapy for hereditary diseases such as «children of the moon» and a common form of colon cancer.

However, when inflammation isn't quick, and targeted, it can cause a state of chronic inflammation leading to disease.