Sentences with phrase «targeting nerve cells»

He thinks targeting nerve cells could be a feasible therapeutic approach for asthma in humans.

Like Zika, West Nile virus and Powassan virus are neurotropic, meaning these pathogens target nerve cells.

Neurons that turn off brain circuits do so by decreasing electrical activity to target nerve cells.

«The signal produced by the PV cell — after stimulation by the PYR cell — was passed on to target nerve cells and prevented them from generating action potentials of their own,» Poulet says.

In the case of GBS, the immune molecules target nerve cells.

Evidence is building that the Zika virus often targets nerve cells.

Next, Singh says, the group should try to improve the specificity of the inhibitor so that it only targets nerve cells.

Adult stem cell therapy is a promising new approach to addressing the disease cycle and resulting symptoms seen in MS. Making use of the powerful healing mechanisms of stem cells present in your adipose (fat) tissue, Okyanos Cell Therapy presents the opportunity to address debilitating MS symptoms while targeting nerve cell repair.

Not exact matches

The start - up's premiere product, the Thin Ice vest, uses cold therapy to target areas of the body with high concentrations of thermoreceptors, which are nerve cells that are able to detect the presence of hot or cold temperatures.

Unlike some of the promising treatments that have failed in 2017 that deal with the so - called «amyloid hypothesis» (the treatments target amyloid beta deposits in the brain that accumulate in people with Alzheimer's disease), approaches that try to prevent nerve cells from dying wouldn't have any impact on that buildup.

Chemotherapy works by killing cancer cells by targeting fast - dividing cells, and in most cases, kills off some healthy cells along the way, including nerve cells in the brain.

Results from the new study suggest immunostimulant molecules that target neutrophils at nerve injury sites might enhance clean - up and promote nerve cell repair.

«The multiple sclerosis drugs currently on the market and being tested elsewhere seek to reduce the immune attack on cells, but none target neurodegeneration nor do they work to restore nerve cell function.

BREAKING DOWN MULTIPLE SCLEROSIS Taking narrow aim at the immune system isn't enough, so researchers are looking for new treatment targets within nerve cells and even in the gut.

If researchers could develop drugs that target those proteins, perhaps they could stop nerve cell death and prevent MS from progressing, the two scientists say.

Based on previous studies, researchers have hypothesized that recreational noise exposure might damage the circuitry between sensory hair cells in the inner ear and their auditory nerve targets that deliver information to the brain.

The Harvard researchers began by analysing the three - dimensional structure of the small region of the nerve cell sheath protein that is targeted by immune cells in MS patients.

In tests on zebrafish, flies and mice, scientists found that treating the disease with purified quercetin — which targets beta - catenin — led to a significant improvement in the health of nerve and muscle cells.

A better understanding of aberrant brain receptor signaling that leads to nerve cell dysfunction could reveal a target for therapy, according to the authors.

The other finding was of a variant near genes for several so - called semaphorins, proteins that guide developing nerve cells as they grow toward their final targets.

Before injecting nematodes with magnetic nanoparticles, the scientists first coated the manganese — iron nanoparticles with polyethylene glycol, a molecule that targeted the particles to the mucus layer of the amphid region (an opening near the nematode's mouth that hosts the nerve cells involved in the heat avoidance reflex).

Whereas in the nematode experiment the researchers targeted nanoparticles to temperature - sensitive ion channels that naturally exist in the membranes of the worms» nerve cells, the scientists inserted the gene for a heat - activated ion channel called TRPV1 into the human and rat cells.

There is no question that the great specificity of any one conscious perceptual experience — such as the throbbing pain of the socket following extraction of the lower right wisdom tooth, the feeling of familiarity in dj vu, the aha experience of sudden understanding, the azure blue of a high mountain vista, the despair at reading about one more suicide bombing — is mediated by coalitions of synchronized cortical nerve cells and their associated targets in the satellites of the cortex, thalamus, amygdala, claustrum and basal ganglia.

A number of radiotherapies that marry a small but potent amount of radioactive material and a targeted molecular compound have been gaining traction as progressive treatments for malignant NETs, which can develop wherever nerve cells and hormone - producing endocrine cells are present (e.g., gastrointestinal tract, pancreas, lungs, thyroid).

When the growing nerve fiber and the target cell finally come in contact, the provisional adhesion consolidates into the structural and functional organization of the synapse.

The solution was targeted to each animal's striatum, a brain region involved in motor control; it is the dopamine - producing nerve cells in this area that die during Parkinson's disease.

In fact, so much of the progress that we're making in laboratories, including mine, is on developing neuroprotective therapies that can protect the retina from degeneration, regenerate optic nerve fibers all the way back to their targets in the brain, and even replace damaged retinal ganglion cells with self - therapies that completely rebuild the optic nerve.

Glutamate, like all neurotransmitters, is a chemical message released by one nerve cell and targeted at another.

These key understandings are the first significant steps toward slowing or preventing the cell death process using targeted interventions to protect the optic nerve from glaucoma's damage.

This enables the doctors to target your stem cells inside the brain to re-establish blood flow and repair damaged nerve cells (neurons).

«Indeed, targeting the fibrinogen - microglia interactions to halt nerve - cell damage could be a new therapeutic strategy,» said Dr. Akassoglou.

Doctors at Okyanos utilize a specifically developed Okyanos protocol for opening up the blood brain barrier to help deliver stem cells directly to the brain; a technique that has been proven effective in independent studies This enables doctors to target your stem cells inside the brain to re-establish blood flow and repair damaged nerve cells (neurons) as well as target the restoration of myelin, halting the future progression of symptoms.

Recent studies of various mouse strains showing «striking differences» in the repair of axons — the long, slender projections in nerve cells that conduct electrical impulses — could be applied to human cells «to identify biomarkers of central nervous system repair potential and provide new targets for intervention,» he says.

Through a five - year National Eye Institute R01 grant totaling more than $ 2.6 million, they will investigate several aspects of how EDN induces neurodegeneration and cell death and how these mechanisms might be targeted therapeutically for early disease prevention, before nerve damage and cell death has occurred.

Understanding the role of glial cells in glaucoma as well as what happens to the optic nerve where the retinal nerve axons leave the eye may present new therapeutic targets and even potential biomarkers of glaucoma.

Yes, nanotechnology is becoming ubiquitous in our daily lives and has found its way into many commercial products, for example, strong, lightweight materials for better fuel economy; targeted drug delivery for safer and more effective cancer treatments; clean, accessible drinking water around the world; superfast computers with vast amounts of storage; self - cleaning surfaces; wearable health monitors; more efficient solar panels; safer food through packaging and monitoring; regrowth of skin, bone, and nerve cells for better medical outcomes; smart windows that lighten or darken to conserve energy; and nanotechnology - enabled concrete that dries more quickly and has sensors to detect stress or corrosion at the nanoscale in roads, bridges, and buildings.

Right now all therapy for glaucoma is directed at lowering eye pressure, but the idea that we could develop therapies and test them in people that really target the retinal ganglion cells and the axon fibers going into the optic nerve — that, I think, is the most exciting new frontier for the premise of restoring vision and protecting vision in glaucoma.

Neurona's initial aim is to develop therapeutic compositions of specialized nerve cells for targeted delivery into the injured nervous system.

The observations that astrocytes and even non-neural cells (J Cell Sci 2004, J Lipid Res 2007) store and can release neurotransmitter amino acids in a way resembling synaptic release, and that oligodendrocytes have NMDA type glutamate receptors (Nature 2005), together with findings that glutamate and other neuroactive substances can be co-released from nerve endings (Eur J Neurosci 2003, Molec Neurosci 2004, Cereb Cortex 2009a), including at the neuromuscular junction (Neuroscience 2007b), suggest novel ways of intercellular communication and potential drug targets.

Researchers at Karolinska Institutet in Sweden now demonstrate in a paper published in Nature that a well - known family of enzymes can prevent the inflammation and thus constitute a potential target for drugs.Research suggests that microglial cells — the nerve system's primary immune cells — play a critical part in neurodegenerative diseases, such as Alzheimer's and Parkinson's.

But other ways of treating the disease, including targeting the other protein called tau that damages nerve cells, may prove important as well.