Sentences with phrase «targeting vaccine antigens»
Ken SHORTMAN, WEHI, Melbourne, AUS «Enhancing protective antibody responses by targeting vaccine antigens to Clec9A on dendritic cells» Host:...
http://www.ciml.univ-mrs.fr/ Not exact matches
Recombinant vaccines rely on one or more antigens — proteins associated with the target bacterium — that boost an immune response; in this case Mycobacterium tuberculosis, which causes TB.
The study size requires screening about 10,000 patients for the presence of the MAGE - A3 antigen that the vaccine targets.
The findings underscore the need for targeted research to further evaluate manufacturing strategies and vaccine antigens and platforms, according to the authors.
The Cancer Vaccine Collaborative is working on treatments that target multiple cancer antigens, which should trigger a more aggressive immune response and increase the odds of defeating tumors.
The albumin - targeted vaccines provoked immune responses five to 10 times stronger than those generated by the peptide antigens alone.
«In addition, our method offers the potential to accelerate the development of new vaccines by allowing the efficient evaluation of candidate target antigens.»
These same models are used to develop new anti-cancer vaccines based on long peptide or DNA vaccination targeting the antigen to antigen presenting cells.
The overall aim of this project is to determine the functional significance of antibody targeted cellular and complement responses to a novel pediatric malaria vaccine candidate antigen, PfSEA - 1.
These are more specific therapies such as monoclonal antibodies and cancer vaccines, which target specific tumor antigens.
discovery of new vaccine targets by innovative approaches that allow the identification of non-classical vaccine antigens like non-protein antigens and subdominant epitopes and novel protein candidates
Robert Schoen, M.D., M.P.H., of the University of Pittsburgh, presented research showing that the tumor - associated antigen MUC1 is a promising target for such a preventative vaccine.
«This loss - of - HLA mechanism suggests that, when designing vaccines and cell - based therapies, we need to target antigens that are presented to the immune system,» says Swanton.
Serogrouping identified isolates expressing capsule antigens targeted by the vaccine.
«We have created a potentially much less expensive approach to making a therapeutic cancer vaccine that, while targeting a single tumor antigen, generates an immune response against multiple antigens.