Sentences with phrase «targets for therapeutic applications»

PrediXcan has the potential to identify gene targets for therapeutic applications faster and with greater accuracy than traditional methods.

Not exact matches

This new technology offers two main advantages based on the use of molecular tools to manipulate the genome: firstly, working models that had not existed up until now for the study of tumour biology and, secondly, their application will eventually allow for the study of new therapeutic targets and therapies.

The role of Apelin and Elabela in establishing the circulatory system makes them potential targets in future development of therapeutic applications for illnesses ranging from the various cancers, and cardiovascular diseases, to even metabolic diseases such as diabetes.

It is still too early to think about its clinical application, but the work reveals a new genetic target on which to look for new possible therapeutic strategies.

But, these squishy packages are hard targets for potential therapeutic and diagnostic applications that exploit nanomaterials, from quantum dots that light up specific tissues to nanocages carrying drug payloads.

Dr. Kirino says that «further studies to understand how SHOT - RNAs promote cell proliferation may lead to the use of SHOT - RNAs as potential target candidates for future therapeutic applications in breast and prostate cancers.»

Its lead therapeutic programs, which leverage the company's expertise in chemistry and structural biology, include DG041, an antiplatelet compound being developed for the prevention of arterial thrombosis; DG051 and DG031, compounds targeting the leukotriene pathway for the prevention of heart attack; and DG071 and a platform for other PDE4 modulators with therapeutic applications in Alzheimer's disease and other conditions.

Successful application depends on two key principles: identifying an appropriate therapeutic gene and successfully delivering it to the target site while maintaining its efficacious properties (e.g., for gene expression).

«The inflammation resolving targeted nanoparticles have shown exciting potential not only for the potential treatment of atherosclerosis as described here, but also other therapeutic areas including wound repair, for example, as described in the Feb. 9 online issue of Journal of Clinical Investigation, in addition to other applications currently underway with our collaborators,» Farokhzad said.

Keiichiro Suzuki, a CRISPR expert from Salk Institute researcher, also not involved in the study, said by email: «Due to the high stability, specificity and ease for biosynthesis, the synthetic CRISPR RNA approach developed in this study will facilitate targeted genetic modification in a variety of human cells for fundamental studies as well as therapeutic applications»

Exposure therapy is widely appreciated as one of the most effective therapeutic treatments for anxiety spectrum disorders; however, it is often underutilized due to problems that present themselves during treatment, such as client unwillingness or hesitancy, or a lack of understanding on the professional's part regarding targeted applications.