In 2016, Dmitry I. Gabrilovich, M.D., Ph.D., program leader of Wistar's Translational Tumor Immunology program, and his research
team identified a marker for myeloid - derived suppressor cells (MDSCs), a population of immune cells implicated in tumor resistance to various types of cancer treatment, including targeted therapies, chemotherapy and immunotherapy.
Not exact matches
A
team led by Margaret Pericak - Vance of Duke University, Jonathan Haines of Vanderbilt University in Nashville, Tennessee, and Allen Roses — a former Duke researcher now in charge of genetics research at the Glaxo Wellcome Company in Research Triangle Park, North Carolina — scanned the DNA of members of 16 large families with a high rate of Alzheimer's, looking at 280 genetic
markers that might help
identify candidate genes.
Australian
team uses genetic
markers to
identify the most viable embryos to eliminate risk of multiple pregnancies
Any
markers the
team may find would likely not be used to screen potential abusers, Rahm says, but rather to
identify people most likely to respond well to treatment, or to confirm a psychiatric assessment.
The
team focused on sections of DNA that they suspected would provide
markers for past population movements and
identified nearly 400,000 DNA positions across the genome in each individual.
The UCLA
team identified 353 DNA
markers from 51 types of cells and tissues and examined how age affects their DNA methylation levels throughout a lifetime.
The collaborative research
team also found a molecular
marker that would help
identify patients most likely to benefit from cabazitaxel treatment.
For instance, company researchers have recently
identified a promising new genetic
marker for a particular cancer; because Avalon already has all the patents filed on the discovery, Carter and the management
team recently gave the scientists the go - ahead to write up two papers on the work.
Next steps for the
team include
identifying microbiota metabolites whose levels are either significantly elevated or depleted during diseases such as IBD or cancer, to find disease - specific
markers and explore possible roles for these metabolites in disease progression.
Our
team proposes using the strains containing all the
identified evolutionary
markers as vaccine candidates for upcoming influenza seasons,» Kainov continues.
The cancer cell
marker that Johnson and her
team identified was a specific change in protein glycosylation, that is, a unique pattern of sugars decorating a protein found on the cell surface.
Once they were able to isolate skeletal muscle cells using the newly
identified surface
markers, the research
team matured those cells in the lab to create dystrophin - producing muscle fibers.
The next step for her
team is to start looking at individuals instead of just populations,
identifying blood
markers and other physiological signals that illustrate how a person is responding to his or her environment, even before needing to go to the hospital.
The research, by a
team at Washington University School of Medicine in St. Louis, also suggests that the size of the brain's right anterior insula may predict the risk of future bouts of depression, potentially giving researchers an anatomical
marker to
identify those at high risk for recurrence.
The next phase of the research will see this
team, in collaboration with clinical colleagues in the Netherlands,
identify early life clinical
markers of the future renal and cardiovascular health of these children.
Within this gene, the deCODE
team identified haplotypes, or specific sets of genetic
markers, that correspond both to significantly increased risk of stroke and to significantly decreased risk.
Using single water molecules as atomic
markers, the
team successfully
identified the atomic species of this surface; result that was additionally confirmed by the comparison of simultaneous AFM and STM measurements with the outcomes of first - principles calculations.