Sentences with phrase «team studying a drug»

Today, Yin is a regeneration biologist and assistant professor at MDI Biological Laboratory in Bar Harbor, leading a team studying a drug that could nudge the human body into regenerating heart muscle.

Not exact matches

Gilead's R&D team brought home a clean sweep for its four Phase III studies adding the experimental drug bictegravir to its backbone HIV therapy.

John Ehrlichman, Nixon's domestic policy adviser, later confessed to Dan Baum, author of another trenchant study of drugs, Smoke and Mirrors (1996), that Nixon's election team was looking for scapegoats.

The students who used the «study drug» were academically diverse: from high - achieving, AP and Honors students looking for a fast alternative to balance their schedules while maintaining a high GPA, to students struggling to keep a minimum GPA to play on a sports team.

The team employed proteomics, the large - scale study of proteins, to identify four on - the - market drugs that successfully quelled symptoms triggered by several of the overabundant proteins.

The studies focused on motor behavior, not mood disorders, but the team found that certain classes of psychotropic drugs, such as the antidepressants known as monoamine oxidase inhibitors, had recognizable, characteristic effects on behavior.

For this study the researchers targeted very specific types of GABA receptors to improve social behaviors with clonazepam, but the team also found that by using a different drug, they could target other GABA receptors and actually reduce the ability to socially interact in normal mice — underscoring that future medications would need to target very specific receptors so as not to diminish the drug's impacts.

In a recent study, working with a team of researchers, Danino demonstrated that bacteria in pancreatic tumors degrade a chemotherapy drug — Gemcitabine — most commonly used to treat patients who have pancreatic cancer.

Monje's team is also studying chemotherapy drugs to treat DIPG.

In a related Environmental Protection Agency study that is still in progress, a team of scientists at the Johns Hopkins Whiting School of Engineering is using gas chromatography and mass spectrometry to detect the presence of various anticonvulsants and anticancer drugs in drinking water.

The new drugs offer the hope of treatment to perhaps thousands of HIV patients who have stopped responding to other medications, says William Towner, medical director of the Kaiser Permanente HIV / AIDS research trials program and member of the study team, which reported its findings online today in The Lancet.

The team studied a lung cancer drug called erlotinib which can be used to treat between 10 and 30 per cent of lung cancer patients.

The team behind this study had worked with a different drug, the plant extract forskolin, in a 2006 study.

Parker's team hope to help the search for novel drugs to treat heart problems by studying how differently shaped structures in the heart make heart muscle work in different ways.

In the most convincing study to date, a team of researchers in Cambridge has shown that a diet high in soya protein can alter women's hormones in a way that mimics the effects of the anticancer drug tamoxifen.

Finally, the research team tested a drug already in clinical trials (IGF - 1) on a cohort of study participants, finding that it provoked a reversal of neural alterations, though the degree of response varied by ASD individual.

The team is already performing additional studies on the molecules that are altered by J147's effect on the mitochondrial ATP synthase - which could themselves be new drug targets.

In this study, a team of researchers from the National Institute on Drug Abuse led by Marilyn A. Huestis, PhD, set out to fill this critical gap in roadside marijuana testing knowledge.

For their part, Carhart - Harris and his team are keen to study other types of psychedelic drugs, including dimethyltryptamine (DMT), sometimes found in a traditional South American brew called ayahuasca.

Led by Bavari and Travis Warren, Ph.D., the USAMRIID team performed a series of studies involving a lethal challenge with Marburg virus in nonhuman primates to determine the efficacious dose and regimen of AVI - 7288, as well as to characterize the drug exposures in animals that produced efficacy.

In a study reported recently in the journal Scientific Reports, a team centered at Tokyo Medical and Dental University (TMDU) identified two molecules that can improve the response of pancreatic cancer to a common chemotherapy drug and also predict the prognosis of pancreatic cancer patients.

Wellems's team was studying chromosome 7 of P. falciparum in search of a gene that renders malaria resistant to the drug chloroquine, when they came across a cluster of five related genetic sequences.

For the study, the team activated AMPK signaling with drugs that have been used medically to protect heart tissue during surgery and in sports to enhance performance because of its blood flow boosting abilities.

In a bid to overcome such barriers to study, Inoue's team designed a system they dubbed iPOLYMER, composed of two binding proteins, FKBP and FRB, and an immunosuppressive chemical and drug called rapamycin.

The team's next step will be to complete studies showing safety of SW033291 - related compounds in larger animals, a required part of the pathway to secure approval from the U.S. Food and Drug Administration for trials in humans.

While Dr. Joseph led this study, he is a part of a team of international researchers studying the drug, which he says has offered patients with metastatic melanoma «truly impressive results.»

«Drug treatments for schizophrenia have barely changed over the past few decades, as they still target dopamine receptors,» says study co-author Dr Andrew McQuillin, head of the UCL Molecular Psychiatry team that first discovered GRM3.

Previous studies have shown the drug to be effective at spurring new bone growth in mice and in humans with osteoporosis, and a U-M research team believes that it may spur new growth in brittle bone disease patients as well.

The link between this drug and ALK and lung cancer was not suspected until 2007, when a team in Japan published a study in Nature that made the connection.

For this study, the team will test Sofosbuvir, a new drug, and Ribavirin, which is used in the treatment with interferon.

Although further studies are necessary, potential clinical applications of the team's finding would involve developing methods or drugs that prevent Mtb from entering M - cells.

In the study, the team fed 25 male - female pairs a drug that suppresses prolactin dissolved in peanut oil and 25 male - females peanut oil only as a control.

The VA - UAB team says, based on its lab studies, that honokiol binds more strongly with EGFR than does the drug gefitinib (sold as Iressa), which is commonly used to treat head and neck cancers.

The study, led by a team in The Research Institute at Nationwide Children's Hospital, is the first of its kind to show these results from an exon - skipping drug — a class of therapeutics that allows cells to skip over missing parts of the gene and produce protein naturally.

Further research on how serotonin works in the human brain is needed, according to study author Dr. Toru Takumi, a senior team leader at the RIKEN Brain Science Institute in Japan, to determine whether drugs like fluoxetine could offer similar potential to treat humans with ASD.

A team of researchers has used a computational modeling approach to analyze and compare the toxic effects of fifteen different drugs on the liver, according to a study in PLOS Computational Biology.

The research team will continue the study for a full three years, as is required by the U.S. Food and Drug Administration (FDA) for a phase I clinical trial.

In the new study, a Danish - Czech - U.S. team first firmed up the drug's anticancer effects by combing through Denmark's unique cancer registry — more than 240,000 cases diagnosed between 2000 and 2013, along with data on the medications each patient took.

«Future research will focus on optimizing the candidate therapies discovered by our team in this study as well as developing biomarkers that can be used to test the efficacy of other potentially promising drugs,» says Dr. Rothstein

A new study shows that a 70 - year - old malaria drug can block immune cells in the liver so nanoparticles can arrive at their intended tumor site, overcoming a significant hurdle of targeted drug delivery, according to a team of researchers led by Houston Methodist.

Genini, Beltran and Aguirre say their results suggest that these drugs or similar ones might have a role to play in the retinal diseases they investigated and perhaps in others that their team is currently studying.

Rotman's team discovered this effect in one study in which participants were introduced to a fictitious pharmaceutical company that produced drugs to treat Parkinson's disease and a bacterial infection called Brucellosis.

The team is currently pursuing further studies of the impact of Part D cost - sharing policies in different disease areas, and hopes ultimately to get a better understanding not only of changes in drug access but also of the long range clinical outcomes and costs associated with any delays or interruptions in treatment.

In a new study, a Danish - Czech - U.S. team found the cancer death rate was 34 % lower for patients in a massive cancer registry who stayed on the drug compared with those who started — but stopped — taking it, the researchers reported this week in Nature.

The research team, led by Renee Goodwin, PhD, in the Department of Epidemiology, analyzed data from the National Household Survey on Drug Use, an annual cross-sectional study of approximately 497, 000 Americans, ages 12 and over.

In the first of the two studies, the research team reviewed published analyses of specialty drug cost - sharing, specifically for the three conditions that attract the largest proportion of specialty drug spending: rheumatoid arthritis, cancer and multiple sclerosis.

A Houston Methodist team led by Mauro Ferrari, PhD and Jenny Chang, MD has received funding from the U.S. Department of Defense to complete preclinical efficacy studies and a future clinical trial testing a breast cancer precision drug.

In one study, the Penn - led team conducted a review of the literature and found evidence that high out - of - pocket costs were generally associated with lower use of specialty drugs.

In their recent study, the UCSF team reports the discovery that a class of commonly prescribed Type - 2 diabetes drugs, called TZDs (thiazolidinediones, such as Actos and Avandia), promoted the conversion of white fat cells into brown (in mice and culture dishes) by stabilizing the PRDM16 protein.

Ingber and his team found that a new class of drug being developed by GlaxoSmithKline could prevent pulmonary edema symptoms in the lung chip — and a separate study confirmed those results in animals.