WASHINGTON (January 16, 2017)-- A synthesized steroid mirroring one naturally made by the dogfish shark prevents the buildup of a lethal protein implicated in some neurodegenerative diseases, reports an international research
team studying an animal model of Parkinson's disease.
Not exact matches
Animals that didn't run, no matter how enriched their world was otherwise, did not improve their brainpower in the complex, lasting ways that Rhodes's
team was
studying.
A
team of researchers published a
study first of its kind in the Journal of Agriculture and Food Chemistry in 2008 analyzing the phytoestrogen content of eggs among other
animal food products and vegetarian substitutes (10).
Nakanishi is coordinating seven
teams to
study the impact of the disaster on soil, plants,
animals, fisheries and forests for the next decade, measuring contamination levels and assessing the long - term threat.
In a new
study in the Proceedings of the National Academy of Sciences the research
team found that after giving mice metformin the
animals displayed reduced symptoms when going through nicotine withdrawal.
Combing the genetic data from a transmission
study in ferrets, a
team led by Thomas Friedrich, a professor of pathobiological sciences at the University of Wisconsin - Madison School of Veterinary Medicine, found that during transmission, when one
animal is infected by another through sneezing or coughing, the process of natural selection acts strongly on hemagglutinin, the structure the virus uses to attach to and infect host cells.
The
team hope to start
animal trials in around September 2015, and if those
studies go well, to move to people in five to ten years.
«Before this
study, it was not known if it is possible to produce sufficient numbers of these cells and successfully use them to remuscularize damaged hearts in a large
animal whose heart size and physiology is similar to that of the human heart,» said Dr. Charles Murry, UW professor of pathology and bioengineering, who led the research
team that conducted the experiment.
Many of these
animals are fierce predators that sit atop the food web, but Laidre's
team found that they are also important subsistence resources: Arctic people hunt nearly 80 % of the
studied populations for food and other uses.
When the
team behind the
study took infrared images of the
animals, they noticed that they were losing a considerable amount of heat through their tails.
Nath's
team is currently developing an
animal model of Nodding syndrome to further
study the disease and test potential therapies.
With a grant from the Morris
Animal Foundation, Antczak, his collaborators Samantha Brooks and Ann Staiger from the University of Florida, and the rest of the
team applied a genomewide association
study to compare the genetic makeup of horses with and without sarcoid tumors at more than 50,000 sites in the equine genome.
The IU
team is now planning
studies in
animals and, ultimately, will look to others to partner on clinical trials that implement the new treatment in humans.
The
team also compared the
animals» responses to the therapy's effects in laboratory cell samples and found that in vitro
studies did not predict how well the viral therapy and immune response would fight tumor cells in vivo.
The
team found that 89 % of the
animal studies were not published at all, making it impossible for the IRBs to know whether the
study had been reviewed by other experts.
The specifics have yet to be ironed out, but the Amgen
team has uncovered a few clues in their rodent
studies: They found treated
animals had increased activation of certain neurons in the brain that detect blood sugar, and this may have helped them sense when it was time to stop eating.
In a new
study, a
team found that injecting mice with tiny magnets and cranking up the heat eliminated tumors from the
animals» bodies with no apparent side effects.
The pilot
study of 40
animals was conducted by a multidisciplinary
team of scientists from the University of Surrey (UK), Universidad de Extremadura (Spain), and SME Ingulados (Spain).
Earlier
studies looked at many genes from a few
animals or a few genes from many
animals, but Brown University biologist Casey Dunn and his
team cast a wider net, sampling DNA from all across the genomes of 71 different
animals.
As director of the Poly - PEDAL Laboratory, a cross-disciplinary
team of researchers — many of them undergraduates — Full is devoted to forming general principles from the
study of
animal motion.
Lima's
team studied the behavior of the
animals before and after specific interventions were put in place.
With so little previously known about the larger Pacific striped octopus, the
team hopes to continue
studying the dietary needs of newly - hatched planktonic larvae to develop a captive breeding protocol and learn more about the
animal's full life cycle.
Based on past
studies from several
animal researchers, the Johns Hopkins
team knew that extinguishing fearful memories requires receptors for the neurotransmitter glutamate.
The
team's discovery that «the collective outcome [the group personality] is different from the sum of the personalities is very cool,» says Noa Pinter - Wollman, an
animal behaviorist at the University of California, San Diego, who was not involved in the
study.
To shed light on the mystery of Bornean elephant's origin, Chikhi and Goossens»
team used genetic data analysis and computational modelling to
study the past demographic history of these
animals.
A previous
study from the MGH
team found that injecting B cells into cardiac tissue damaged by a heart attack improved structural and functional recovery in an
animal model.
Yong, a neuroscientist, initially had the idea to test the acne medicine in an
animal model since minocycline has many anti-inflammatory properties that he thought could be useful in treating MS. Soon after obtaining successful research results, in
studies also supported by the MS Society of Canada and MSSRF, Yong
teamed up with Metz who led the transition into a pilot clinical trial, then a Phase 2, and finally the definitive Phase 3 trial.
For the JCI
study, the
team applied the radiotracer to monitor olfactory sensory neuron population dynamics in a rodent model, using PET to measure its uptake across the
animals» lifespan, including during age - related neurodegeneration.
Although c9, t11 also showed some weak anti-inflammatory action in the
team's test - tube
studies, it failed to curb inflammation in
animals.
The
study was performed in Kilpisjärvi in northwest Finland, where the research
team tested the importance of grazing
animals, warming and nutrient availability by combining small greenhouses that increased the summer temperature by 1 - 2 degrees Celsius, small fences that excluded reindeer, voles and lemmings, as well as by use of fertilization.
As part of a DNA
study of the world's cats, Stephen O'Brien and his
team at the National Cancer Institute (NCI) in Frederick, Maryland, collected blood and tissue samples from 209 puma in zoos, museums, and the wild across North and Central America, and from 106 of the
animals in South America.
Led by Bavari and Travis Warren, Ph.D., the USAMRIID
team performed a series of
studies involving a lethal challenge with Marburg virus in nonhuman primates to determine the efficacious dose and regimen of AVI - 7288, as well as to characterize the drug exposures in
animals that produced efficacy.
The same likely holds true for other
animals, predicts the Uppsala University
team that helped conduct the rabbit
study.
Dr. Lyons and his
team used zebrafish to
study the formation of myelin sheaths by oligodendrocytes because this laboratory
animal is transparent at early stages of its development, which allows investigators to directly observe cells within the organism.
In each
animal, the
team studied 7100 bases, the letters that define genes.
Using a combination of human or specially engineered mouse cells in vitro and in vivo
animal models,
study senior investigator Judy Lieberman, MD, PhD;
study lead investigator Farokh Dotiwala, PhD, with a
team lead by the Brazilian parasitologist Ricardo Gazzinelli, DSc, DVM, found that when an immune killer cell, such as a T - cell or natural killer (NK) cell, encounters a cell infected with any of three intracellular parasites (Trypanosoma cruzi, Toxoplasma gondii or Leishmania major), it releases three proteins that together kill both the parasite and the infected cell:
The
team's next step will be to complete
studies showing safety of SW033291 - related compounds in larger
animals, a required part of the pathway to secure approval from the U.S. Food and Drug Administration for trials in humans.
To make their new
study, the
team — including scientists from University of Oxford, University of Vermont, Harvard University, Aarhus University in Denmark, Princeton University, Netherlands Institute of Ecology, and Purdue University — used these findings and other existing data about historic and current
animal populations.
Scientists
studying the potential effects of climate change on the world's
animal and plant species are focusing on the wrong factors, according to a new paper by a research
team from the Wildlife Conservation Society, University of Queensland, and other organizations.
When the
team injected the vaccine into the skin of macaque monkeys, the reaction was similar to that in humans, but when injected into the bloodstream, the vaccine provided a strong and long - lasting CD8 + response in all three
animals studied.
ASCB President Don Cleveland of the University of California, San Diego, said his
team just published an
animal study on a gene silencing therapy for treating a form of Lou Gehrig's disease that they now hope to move to clinical
studies.
The
team found that out of the nearly 150 pathogens
studied, 75 caused visible symptoms in
animals, such as seizures, lethargy, unprovoked aggression, or death, meaning signs of the disease could be easily detected.
The one research
team that has
studied chimpanzee enclosure size in zoos concluded that once the
animals have at least 12.2 square meters per individual, the benefits of more space taper off, NIH says in a notice today.
For their
study, the
team flooded a line of Escherichia coli (a common bacterium that lives harmlessly in the intestinal tracts of many
animals, although some strains can cause food poisoning with antibiotics, killing some of cells but leaving behind a gaggle of stubborn ones.
The research
team tested the hypothesis by transplanting cells onto the surface of mouse bone grafts and
studying the cell behavior both in vivo — inside the
animal — and in vitro — outside the body.
Along with the
studies in live
animals, the research
team also
studied human brain tissue from Northwestern's Cognitive Neurology and Alzheimer's Disease Center.
The
team of researchers
studied stable carbon isotopes in the tooth enamel of the large primates — which are able to reveal information about the
animals» dietary habits even after several million years.
Some
teams are
studying the potential of stem cells and others try to understand why some
animals can regenerate.
A
team of Japanese scientists has discovered a new species of polychaete, a type of marine annelid worm, 9 - meters deep underwater near Japan's Syowa Station in Antarctica, providing a good opportunity to
study how
animals adapt to extreme environments.
The
team studied Cryptococcosis, a disease that infects humans and
animals after breathing in airborne fungi.