Sentences with phrase «team transplanted the cells»

When the team transplanted the cells into diabetic mice whose own beta cells had been destroyed artificially with a chemical, the cells acted like healthy beta cells.

Not exact matches

Da Cruz and his team grew replacement RPE cells from human embryonic stem cells on a thin plastic scaffold, before transplanting the tissue into the back of each volunteer's eye.

Luznik and his team inventoried types of immune cells present in the blood of bone marrow transplant patients treated with post-transplant cyclophosphamide.

The team also transplanted treated fibroblasts into the hearts of live mice, where they developed into cardiomyocytes (Cell, DOI: 10.1016 / j.cell.2010.07.002).

The team has already successfully repopulated pig kidneys with human cells, but Ott says further studies are vital to guarantee that the pig components of the organ do not cause rejection when transplanted into humans.

Craig Venter «s team at the J. Craig Venter Institute in Rockville, Maryland, and San Diego, California, has made a bacterial genome from smaller DNA subunits and then transplanted the whole thing into another cell.

On average the transplanted stem cells regenerated 40 percent of the damaged heart tissue, said Dr. Michael Laflamme, UW assistant professor of pathology, whose team was principally responsible for generating the replacement heart muscle cells.

Jacob's team has transplanted the back - up or «alternative» respiratory machinery from the mitochondria of lower organisms to human cells, showing that it can protect against pathological stresses, and even lethal poisons like cyanide, that target the mitochondria.

In this study, Cherqui's team transplanted wildtype HSPCs into an FA mouse model, reporting that the HSPCs engrafted and soon differentiated into macrophages in key regions of the mice's brain and spinal cord where they appeared to transfer wildtype FXN into deficient neurons and muscle cells.

Unlike the first synthetic cells made in 2010, in which Venter's team at the J. Craig Venter Institute in La Jolla, California, copied an existing bacterial genome and transplanted it into another cell, the genome of the minimal cells is like nothing in nature.

«Just one transplant of the human EPO - producing cells treated kidney anaemia in mice, keeping their haemoglobin levels in the normal range for the remaining 7 - month lifespan of the animals,» says Kenji Osafune, of Kyoto University in Japan, who led the team.

The team then transplanted these cells into the kidney cavities of mice with a form of kidney anaemia.

The team could isolate muscle stem cells from the male mice before they died and when they transplanted them into muscle - damaged recipient mice, they found that the stem cells were able to regenerate new muscle.

Because previous work in rats and monkeys has found that proteins that block the costimulatory signal can hold T cells at bay, Kim Olthoff, a transplant surgeon at the University of Pennsylvania Medical Center in Philadelphia, thought her team could achieve a targeted immune suppression by getting the transplanted organ itself — rather than proteins injected into the bloodstream — to block the costimulatory signal.

Zavazava's team is among several groups aiming to create an alternative source of insulin - producing pancreatic cells that can be transplanted into patients with type 1 diabetes.

One team has grown lung cells that performed their gas - exchange functions when transplanted into living rats.

Sacha's team has shown a species of monkey called Mauritian cynomolgus macaques can successfully receive stem cell transplants.

Yong - Chun Yu at Fudan University in Shanghai, China, and his team wondered if fearful adult mice could be helped by a transplant of embryonic brain cells.

Now, in a study recently published in the journal PLOS ONE, a team of scientists from VCU Massey Cancer Center have shown a genetic relationship between the reactivation of hCMV and the onset of graft - versus - host disease (GVHD), a potentially deadly condition in which the immune system attacks healthy tissue following a bone marrow or stem cell transplant.

Furthermore, when the team suppressed STAP - 2, the prostate cancer cells showed reduced proliferation and did not form a tumor when transplanted into mice.

Today, at 56, Atala oversees 300 researchers and support personnel, including chemists, biologists and engineers divided into different teams working on cell therapy, a technology for what he calls partial transplants and the creation of new organs.

After generating T cells against cytomegalovirus, medical biotechnologist Erica Dander, 26, wrote in collaboration with her multi-disciplinary team a successful clinical trial protocol to test whether injecting the T cells could kill infected cells in transplant patients.

The research team tested the hypothesis by transplanting cells onto the surface of mouse bone grafts and studying the cell behavior both in vivo — inside the animal — and in vitro — outside the body.

A team of researchers led by Andreas Beilhack and Harald Wajant of the University Hospital W?rzburg devised an alternative way to prevent GvHD in mice, developing a protein called STAR2 that can stimulate the formation of the transplant recipient's own T reg cells in vivo.

To investigate how zebrafish tails take shape, Thisse's team removed some of the presumed pre-tail cells from early - stage embryos, then transplanted them into the middle of another embryo.

Yoshizaki's team first performed some germ cell transplant operations.

Previous work from the Cambridge team has shown that transplanting neural stem cells (NSCs)-- stem cells that are part - way to developing into nerve cells — reduces inflammation and can help the injured CNS heal.

The research team has not directly tested whether the transplanted RPE cells improved the animal's vision.

Then his team used a drug (not the test compound) to kill each mouse's liver before transplanting human liver cells into their bodies.

Takahashi's team transplanted retina cells made from the patient's skin cells into the patient's eye with the goal of treating macular degeneration.

The team used a specific mouse strain that is healthy but it is lacking in a specific immune cell receptor, which makes the mouse unable to reject transplanted foreign cells.

More than 20 years ago Munson McLeod underwent a successful stem cell transplant to conquer his non-Hodgkin lymphoma by a caring, dedicated team at Rutgers Cancer Institute of New Jersey and Robert Wood Johnson University Hospital.

At the University of Chicago Medicine, the same team of expert physicians and nurses who provide inpatient blood and bone marrow stem cell transplant care oversee the outpatient program.

A team of UK stem cell scientists, led by Dr. Robin Ali from UCL Institute of Ophthalmology in London, has developed a new strategy for repairing the retina by transplanting photoreceptor cells generated in the laboratory from embryonic stem cells.

The team transplanted stem cell - derived photoreceptors into another strain of mouse, called CRX null, which is congenitally blind.

(Medical Xpress)-- A team of researchers affiliated with several institutions in Japan has succeeded in growing kidneys from stem cells that worked as they were supposed to after being transplanted into rats and pigs.

Two researcher teams — led by Professor Min Zhao at the University of California, Davis, School of Medicine's Institute for Regenerative Cures and Junfeng Feng, a neurosurgeon at Ren Ji Hospital, Shanghai Jiao Tong University and Shanghai Institute of Head Trauma — worked together to developed a model of stem cell transplants in rats.

Importantly, the team also found that, in mice, antibody - mediated stimulation of this receptor following a bone marrow transplant increased the number of donor - derived T - cells and boosted initial thymus recovery.

Up close, huddled inside the Centeno - Schultz Pain Center, I joined a team of MDs, a PhD, and two nurses to witness orthopedic history in vivo: an adult stem cell (ASC) transplant to help bones and joints grow anew.

When I was in the hospital for a stem cell transplant — the medical team took measurements of temperature, blood pressure and blood samples every 4 hours.

A research team led by Michal Schwartz of Israel's Weizmann Institute of Science grew these immune cells in a laboratory and implanted them into rats, and the transplants of the cells caused the axons to regenerate.