Sentences with phrase «tegmental area of»

Here we used shRNA to model Shank3 insufficiency in the ventral tegmental area of mice.

12 Can't Get Enough of Your Love: Dopamine is produced in the ventral tegmental area of the brain, the same region affected by addictive drugs like cocaine.

Not exact matches

Looking inside the brains of animals exposed to chronic social defeat stress, the scientists observed hyperactive firing of neurons in the ventral tegmental area (VTA), a critical part of a reward circuit.

To regulate mood, the prefrontal cortex acts as a pacemaker to coordinate the actions of the amygdala, which governs stress responses, and the ventral tegmental area, which plays a role in the brain's reward circuitry.

Mice in booze camp In the new study, performed on adolescent male mice, ethanol alcohol exposure seemed to enhance synaptic plasticity in the ventral tegmental area (VTA), a part of the brain that plays a critical role in the reward pathway.

Drugs of abuse impact the ventral tegmental area (VTA) of the brain, which is rich in dopamine neurons.

The U.C. San Francisco team had previously shown that upping levels of GDNF into a part of the brain associated with drug addiction (the ventral tegmental area) dramatically curtailed the animals» habits.

Between - group analysis of phase 2 demonstrated a significant activation cluster in the ipsilateral posterior insula (pIns) in group P. Using the pIns as a seed region the PPI analysis yielded a significant enhanced coupling to the midbrain (periaqueductal grey / ventral tegmental area) after analgesia onset in group A only.

The blunted dopamine signaling to ethanol arose due to changes in the circuitry in the ventral tegmental area, the heart of the brain's reward system.

Neuroscientists know that a particular brain structure, the ventral tegmental area, or VTA, is the origin of numerous dopamine - secreting nerve fibers that run in discrete tracts to many different parts of the brain.

«Resilient mice overcome this change by counteradapting their gene expression [the suite of genes that act on the nucleus accumbens that are either turned on or off] to clamp down the levels of activity in the ventral tegmental area.»

More specifically, in a 2012 review of the love research literature Lisa Diamond and Janna Dickenson, psychologists at the University of Utah, found romantic love is most consistently associated with activity in two brain regions — the ventral tegmental area (VTA) and the caudate nucleus.

Until now, the area of the brain where these neurons are found, called the ventral tegmental area (VTA), had only been associated with the reward system — not stress from withdrawal.

An ancient structure called the ventral tegmental area (VTA) controls our ability to use past experience as a predictor of future reward.

Through the combined use of in vivo microdialysis and behavioral and neuropharmacological techniques, his early work characterized the role of serotonin and its signaling via serotonin - 1B (5 - HT1B) receptors in the ventral tegmental area, nucleus accumbens, and ventral pallidum in the rewarding actions of cocaine and ethanol.

For example, he demonstrated that nicotine - induced formation of the endocannabinoid 2 - AG in the ventral tegmental area is sensitized following chronic nicotine exposure.

Upon intake of alcohol, the absence of the RASGRF - 2 impaired the activity of dopamine - releasing neurons in a region of the brain called the ventral tegmental area (VTA) and prevented the brain from releasing dopamine, and hence any sense of reward.

They focused on one of its major pathways, the ventral tegmental area (VTA), which the mPOA use to transmit messages to other parts of the brain.

Collectively, these data reveal the contribution of impaired ventral tegmental area function to social behaviors and identify mGluR1 modulation during postnatal development as a potential treatment strategy.

Previous research in the laboratory of Daniel McGehee, PhD, neuroscientist and associate professor in the Department of Anesthesia & Critical Care at the Medical Center, discovered that nicotine could promote plasticity in a region of the brain called the ventral tegmental area (VTA).

When we do something pleasurable, a bundle of neurons called the ventral tegmental area uses the neurotransmitter dopamine to signal to a part of the brain called the nucleus accumbens.

Your brain's pleasure center (aka ventral tegmental area, or VTA, and nucleus accumbens, or NA) is the root of all behavior, driven by chemical messengers that are intimately tied into the energy processes I have outlined above.

The team's scans revealed a tiny area of the brain called the ventral tegmental area (or VTA for short) lighting up when the study's participants were shown a photo of their beloved.

«Love triggers the parts of the brain associated with reward,» van der Walt says, «in neuroscience terms this is the caudate nucleus and the ventral tegmental, areas of the brain that release the neurotransmitter dopamine.»

Mobbs saw that subjects» brains became highly activated for all the cartoons, but one subset of structures responded solely for the funny ones — namely, the ventral tegmental area, the nucleus accumbens, and the amygdala.

In the earlier stages of love, other brain areas such as the caudate nucleus and the ventral tegmental areas become active.