Sentences with phrase «telomerase antigen»
Our AST - VAC immunotherapy programs employ three common elements of dendritic cells, telomerase antigen, and the LAMP signal sequence to stimulate robust and specific immune responses to cancer cells (Figure 1).
http://asteriasbiotherapeutics.com/
Asterias maintains an extensive global intellectual property portfolio including broad issued claims to fundamental platform technologies including, but not limited to, scalable growth of pluripotent stem cells, methods of production and compositions of matter for several hESC - derived therapeutic cell types, and cellular immunotherapy using the telomerase antigen.
Not exact matches
These cells were immortalized by retroviral transduction of the SV40 T antigen and Telomerase reverse transcriptase (TERT), the catalytic subunit of the telomerase complex [4], and then termed HMLE (Human Mammary with Large T Telomerase reverse transcriptase (TERT), the catalytic subunit of the telomerase complex [4], and then termed HMLE (Human Mammary with Large T telomerase complex [4], and then termed HMLE (Human Mammary with Large T and TERT).
Our vaccines also employ the LAMP sequence, licensed from Immunomic Therapeutics, to optimize antigen presentation, increasing immune responses to telomerase.
Additionally, the allogeneic platform has the flexibility to leverage alternative antigens beyond telomerase, which could extend AST - VAC2 applications even further.