The new research, which studied the immortalization process using genome - engineered cells in culture and also tracked skin cells as they progressed from a mole into a malignant melanoma, suggests that
telomerase plays a more complex role in cancer.
«Two - step process leads to cell immortalization and cancer: Clearer view of the role telomere length and
telomerase play in cell immortalization.»
Not exact matches
Although de Lange notes that telomere shortening needs further investigation, she says there's now no doubt that telomeres
play a critical role in limiting human cell division and that
telomerase can reactivate the process.
«That makes fooling with
telomerase look like child's
play.»
Telomerase is an enzyme responsible for the production of telomeres, which
play an important role in the regulation of normal cell division.
Telomerase is believed to
play a role in the normal development of progenitor cells.
Dr. Blackburn won the Nobel Prize in Physiology or Medicine in 2009 for discovering the molecular nature of telomeres and for co-discovering the enzyme
telomerase; both telomeres and
telomerase are thought to
play central roles in aging and diseases such as cancer.