While
telomerase production decreases almost entirely in healthy adult cells, it increases in cancerous cells.
A study conducted by California's Preventive Medicine Research Institute saw
telomerase production boosted by 29 percent in 24 patients who switched from a sedentary lifestyle to one defined by exercise, healthy diet and stress management.
In fact, some scientists propose decreasing
telomerase production as a means of fighting cancer.
As you might expect, these facts complicate the notion of boosting
telomerase production to stop ageing.
Not exact matches
An estimated 90 percent of all malignant tumors use
telomerase to achieve immortality, and various proposed cancer therapies focus on turning down the
production of
telomerase in tumors.
One strategy, which occurs in about 90 percent of cancers, requires increase
production of a telomere - elongating enzyme called
telomerase.
Telomerase is an enzyme responsible for the
production of telomeres, which play an important role in the regulation of normal cell division.
With arsenic forcing the
production of largely useless
telomerase in cell lines that simulate acute promyelocytic leukemia, the chromosomes in cancer cells fuse together, causing the cell death that helps fight the cancer.
Asterias maintains an extensive global intellectual property portfolio including broad issued claims to fundamental platform technologies including, but not limited to, scalable growth of pluripotent stem cells, methods of
production and compositions of matter for several hESC - derived therapeutic cell types, and cellular immunotherapy using the
telomerase antigen.
Using PET scanning, they saw that KKM resulted in 19 genes being up - regulated and 49 genes being down - regulated, resulting in the
production of fewer inflammatory mediators, and increased
telomerase activity by almost 50 %.
In one study, researchers found that a compound within astragalus activates
production of the
telomerase (hTERT) enzyme.