Sentences with phrase «telomeres become»

Because telomeres become shorter as a cell ages, we can test the length of telomeres to gain a picture of the aging process.
If telomeres become excessively diminished, the cell will become inflamed and eventually die.
As time passes, telomeres become shorter; their length is an excellent predictor of health and longevity, and a lot of research on aging focuses on how to protect them from shortening.
As time passes, telomeres become shorter, which leads to aging and chronic disease.
These telomeres become shorter every time a cell divides, which hinders their ability to ensure that the new cells are identical to the parent cells.
Over time, the telomeres become too short for the cell to divide and they become «senescent.»
One key difference between telomeres and cassette leaders is that leaders stay intact as long as the tape does, whereas telomeres become ever - so - slightly shorter every time the cell replicates itself or is hit by damaging agents like free radicals.
The more chronically stressed we are, the shorter our telomeres become.

Not exact matches

Located at the ends of chromosomes, telomeres typically shorten with each cell division, until the end of the chromosome becomes so frayed that the cell dies.
Over time, these mobile elements accumulated and became the telomeres, says Villasante.
Telomerase periodically relengthens the telomere before it becomes critically short.
The telomeres, therefore, become a little bit shorter with each cell division process.
Therefore, adult stem cells become exhausted in aged individuals due to telomere length shortening that results in increased healing times and organ tissue degradation from inadequate cell populations.
In embryos where the telomerase gene was deleted, the telomeres of all embryos became shorter than normal.
The limitation may be that normal cells do not produce active telomerase, which can rebuild the telomeres and keep cells from becoming senescent.
Telomeres» initial length varies among individuals, but in everyone, they become shorter over time.
Cell - culture studies show that when telomeres can no longer shield chromosomes from damage, cells stop dividing or become unstable.
No matter where the source of their DNA, as soon as the embryos became hollow balls of cells, between the developmental stages known as blastocyst and morula, telomerase lengthened telomeres to the right size.
When the telomeres are worn away, the chromosomes become vulnerable to mutations, possibly paving the way for age - related diseases such as atherosclerosis and certain cancers.
Telomeres — repeating DNA sequences at the ends of chromosomes that become shorter with each cell division — have long tantalized biologists seeking to understand and control the aging process.
In cancerous cells, telomerase somehow becomes reactivated, and the telomeres begin growing again.
Telomeres do, however, gradually become shorter, a process that is partly responsible for the aging process.
If telomeres get too short, the cell can no longer divide and becomes inactive or dies.
Thus, the possibility of premature aging in the IVC animals arises, which may become evident in the telomere machinery regulation, since Terc transcription was significantly higher in the IVC testes.
Shorter telomeres have recently been linked to risk of certain cancers, and telomeres are known to become shorter with the accumulation of environmental insults over time.
In the year 2092, Nemo Nobody is a 118 - year - old man who finds himself as the last mortal amongst humans who have become immortal due to scientific advances from the perpetual rejuvenation of telomeres.
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