Sentences with phrase «telomeres found»

The secret to higher HGH levels and longer life may be in telomeres found at the ends of our chromosomes.

Doing so keeps the telomeres found on the ends of your DNA strands long and able to protect chromosomes from deterioration.

Not exact matches

Blackburn conducted research focused on mothers caring for children with autism and other chronic conditions, and found that moms who were more resilient to stress — perceiving their situation as a challenge, rather than something hopeless or overwhelming — kept their telomeres longer.

In case you haven't heard enough about how beneficial meditation can be, here's another way researchers have found that it helps: Family members who meditated for as little as 12 minutes a day for two months while caring for a relative with dementia improved their telomere maintenance.

In people with recurrent depressions, a correlation could also be found between low cortisol levels and short telomeres.

The finding is surprising because this was not a study of telomere length.

Researchers from several institutions, including, UCLA, Boston University, Stanford University and the Institute for Aging Research at Hebrew SeniorLife, analyzed blood samples from nearly 10,000 people to find that genetic markers in the gene responsible for keeping telomeres (tips of chromosomes) youthfully longer, did not translate into a younger biologic age as measured by changes in proteins coating the DNA.

The team found that telomere length was especially affected in larger males, compared with females or smaller males.

For instance, one small study found that people who ate healthier diets, did yoga or meditation, and exercised daily increased the activity of telomerase, which could lead to longer telomeres.

Telomere length does seem to be linked to life span; one key study in The Lancet found that otherwise - normal people over 60 who started out the study with short telomeres were more likely to die over the next 17 years than those with long telomeres.

Now, in a move that brings these questions into sharper focus for the general public, Telome Health, founded by Elizabeth Blackburn, who won the Nobel for Medicine for her work in this area, has announced that it will bring to market a test for telomere length.

Their findings: the telomeres of subjects who exercised the most (an average of 199 minutes weekly) were longer than those of volunteers who worked out the least (a mere 16 minutes or less a week).

A large - scale genetic study of the links between telomere length and risk for five common cancers finds that long telomeres are associated with an increased risk of lung adenocarcinoma.

And five months later, Jerry Shay and Woodring Wright of University of Texas Southwestern Medical Center, also working with Geron collaborators, published additional findings, showing that, by introducing the hTRT gene to cells, they could make those cells repair unraveling telomeres.

Surprisingly, the researchers found no associations between shortened telomeres and cancer risk.

They found that longer telomeres were significantly associated with increased risk for lung cancer — specifically lung adenocarcinoma, which more than doubled in risk for every 1000 base pair increase in telomere length.

Such a lag time, says Hahn, could allow cancer cells to develop resistance to a drug by finding some other way to maintain their telomeres.

To search for new enzymes that could repair telomeres, the researchers — Susan Smith, Titia de Lange, and their colleagues at Rockefeller University in New York City — used a biochemical screen to find substances that interact with TRF1, a human protein known to bind to telomeres.

Great tits raised in an urban environment have shorter telomeres — protective caps at the ends of chromosomes — than those raised in rural environments, researchers find.

«The findings from our study validated recent findings on the telomere binding role of ZBTB48.

The finding also resolves another recent counterintuitive finding: that people with shorter telomeres are more resistant to melanoma.

Telomeres are the protective tips found at the end of each DNA strand and are indicative of cellular aging.

«We also found an association between telomere shortening and thiamine deficiency (TD),» said Yamaki.

Blackburn and UCSF psychologist Elissa Epel's work found that the most stressed - out women had shorter telomeres that translated into an extra decade or so of aging compared with their matched controls — showing that external stressors can throw a monkey wrench into the cell's molecular mechanics.

Researchers chased the gene down and found it was a mutant telomerase RNA gene component, and patients had about half the normal amount of telomerase, which meant their telomeres shorten prematurely.

She found that ASF1 loss initiated an intra-nuclear ping - pong game: cells replicated the tag and then tossed it back and forth between different chromosomes in order to build disorganized but serviceable telomeres.

The researchers found that individuals carrying a particular genetic variant had shorter telomeres — meaning less padding for those fragile genes.

They found that the inactivation of POT1 caused by these mutations leads to longer and potentially unprotected telomeres, regions at the end of our chromosomes that protect chromosomes from damage.

The finding relates to telomeres, the caps that protect the tips of chromosomes when cells divide.

Telomeres are repetitive nucleotide sequences found at the end of chromosomes which protect them from deteriorating during the process of replication.

They found that women with the lowest number of eggs also had the shortest telomeres — the chromosome caps that wear away as cells age — in their white blood cells.

«We have previously found that shag chicks that experience higher levels of stress during development have greater telomere loss.

Scientists at King's College London have found that people who have previously suffered from acne are likely to have longer telomeres (the protective repeated nucleotides found at the end of chromosomes) in their white blood cells, meaning their cells could be better protected against aging.

They found that when chicks first hatched, there was no effect of parental age on offspring telomere length, suggesting there were no pre-natal effects of parental age.

Researchers found she had prematurely shortened telomeres, protective caps on the ends of chromosomes that reduce with age.

Brazilian scientists from the D'Or Institute of Research and Education (IDOR) and the Federal University of Minas Gerais (UFMG) found that ADHD kids and their mothers are more likely to have shorter telomeres, a hallmark of cellular aging, which is associated with increased risk for chronic diseases and conditions like diabetes, obesity and cancer.

Intriguingly, the study also found that drugs called statins, which are better known for their cholesterol - lowering properties, appeared to alleviate the effects of telomere damage — and may even have protected telomeres against degradation.

Even among the children, who are beginning their lives, researchers found shorter telomeres than those that would be expected for their ages.

All six studies looking specifically at LTL found reduced telomere length in persons with PTSD.

Although mother's telomeres were also shorter, they did not find any alteration in the father's telomere length.

The findings underscore the importance of intervening early to address behavior issues in children to prevent psychosocial stress and shortening of telomeres.

Reducing sedentary activity appears to lengthen telomeres, which sit on the end of chromosomes, the DNA storage units in each cell, the findings show.

This was a key finding, as telomeres serve important functions in cell division and protecting mammalian chromosomes.

Adding telomerase to dividing cells in culture can lengthen their lifespan (ScienceNOW, 13 January 1998), but no one has found a direct link between telomeres and animal aging.

The study demonstrates that RingoA is active at telomeres — structures that protect the ends of chromosomes and where Cdk2 is also found.

When researchers took a close look at the cells of Dolly, the cloned sheep, they found that her telomeres, the caps on the ends of the chromosomes, were shorter than normal.

They found that women who reported low socioeconomic status as kids and who struggled with family support as adults were biologically older, as indicated by shorter telomeres.

The researchers also found that parental homeownership in both early childhood and adolescence were both associated with adult telomere length.

They also measured HDL cholesterol, cardiorespiratory fitness, lung function and the length of the telomeres — protective caps at the end of chromosomes that have been found to shorten with age.

In this context, telomerase activity can have unfavorable effects: «We found that this enzyme allows cells with aneuploidy to bypass the protective function of telomeres.