Sentences with phrase «telomeres play»
Telomeres play a pivotal role in how we age and how long we live.
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Functional telomeres play a key role in maintenance of genome integrity, DNA damage response and repair [2, 3].
The idea that shrinking telomeres play a role in organismal aging had been hyped in the media and by Geron's public relations division, she says.
Although de Lange notes that telomere shortening needs further investigation, she says there's now no doubt that telomeres play a critical role in limiting human cell division and that telomerase can reactivate the process.
Not exact matches
«Two - step process leads to cell immortalization and cancer: Clearer view of the role telomere length and telomerase play in cell immortalization.»
Some of the sequence matched repetitive DNA in telomeres, the caps of chromosomes, which often shorten each time a cell divides and play an important role in aging.
Telomeres are not the end of the story, but they play a role.
Dysfunction in telomere maintenance pathways plays an integral role in aging, cancer, and certain rare diseases such as dyskeratosis congenita (DC).
A molecular biologist born in Hobart, Australia, Blackburn is best known for her 2009 Nobel Prize — winning discovery of telomeres, caps on the ends of chromosomes that protect genetic information from damage and are thought to play an important role in aging and cancer.
Telomerase is an enzyme responsible for the production of telomeres, which play an important role in the regulation of normal cell division.
The gradual erosion of telomeres — the strands of DNA that cap our chromosomes and wear away with each cell division — may play a pivotal role in heart disease.
The isoforms of this histone play complex regulatory roles in several cellular processes — epigenetic regulation of gene expression, selective regulation of developmental genes, and telomere maintenance — that could contributed to tumor growth and progression if dysregulated.
Dr. Blackburn won the Nobel Prize in Physiology or Medicine in 2009 for discovering the molecular nature of telomeres and for co-discovering the enzyme telomerase; both telomeres and telomerase are thought to play central roles in aging and diseases such as cancer.
Telomere maintenance has been proposed to play a central role in human aging by limiting the replicative potential of somatic cell populations and... >> MORE
Telomeres will continue to gain momentum as a hot topic, having already been a focus of the 2014 documentary film, The Connection, and playing a central role in Cameron Diaz's next book, a follow - up to her bestselling The Body Book.
I am currently taking 4 herbs which are reputed to play a role in something called «telomere extension».
Interestingly, increased glutathione levels may actually play a role in stopping telomere (9) shortening, which is one of the most exciting anti-aging discoveries in recent years.