There are lots of caveats about
temporal resolution in the paleo data, and I'm probably not up to date on the latest, but the lags between warming and CO2 outgassing you mention were thought to be something like 800 years.
Moreover, conformational changes of single proteins and molecular motors can be recorded with sub-nanometer accuracy and
a temporal resolution in the tens of microseconds.
A key to a mechanistic understanding is the ability to observe membrane organization with a spatial resolution on the molecular level,
a temporal resolution in the micro-second range and sensitivity down to the single molecule without disturbing the system (noninvasive).
Unlike other studies on p53, however, which target cell populations that average many cells together, Dr. Lahav developed a new approach, quantifying p53 at high
temporal resolution in single cells and taking into account that «individual cell decisions are crucial in the development and treatment of cancer.»
NIRSIT, a functional near - infrared spectroscopy neuroimaging device, is set to change the landscape of neuroscience research and the medical sector by offering high spatial resolution as well as high
temporal resolution in a portable and wireless manner.
As the method can be automated, it might be possible to obtain data on biodiversity in an unprecedented spatial and
temporal resolution in the future.
Silvio Rizzi and Joe Insley, Argonne Leadership Computing Facility, Argonne National Laboratory This shows the HACC cosmology simulation, which combines high spatial and
temporal resolution in a large cosmological volume.
Not exact matches
At this point I would like to draw attention to Hartshorne's
resolution of one serious problem
in metaphysics itself, the problem of
temporal relations.
The field of live - cell imaging has expanded greatly
in recent years, but still faces many challenges, such as how to improve spatial and
temporal resolution as well as how to keep cells healthy for extended periods of time.
Imaging with single electrons can track structural dynamics of gold and graphite
in real space with femtosecond
temporal resolution and angstrom spatial
resolution.
We generated knockout mice lacking synaptobrevin / VAMP 2, the vesicular SNARE protein responsible for synaptic vesicle fusion
in forebrain synapses, to make use of the exquisite
temporal resolution of electrophysiology
in measuring fusion.
In this Perspective, Wolf and Ertl discuss results by Kliewer et al. (page 1399) and Petek et al. (page 1402), which illustrate the fundamental insights into the microscopic characteristics of electron dynamics at surfaces that can be obtained by state - of - the - art high spatial and
temporal resolution studies.
It's also light - tunable, non-invasive and has great
temporal resolution —
in other words, it can be turned on when it is needed and turned off when it is not.
IRIS can resolve solar features only 150 miles
in size, has a
temporal resolution of a few seconds, and has a spectral
resolution capable of measuring plasma flows of a few miles per second.
«Applying these analysis concepts to multichannel long - term EEG recordings from 17 epilepsy patients with high
temporal resolution allowed us to derive a sequence of functional brain networks spanning several days
in duration,» said Christian Geier, a doctoral student working with Lehnertz.
It also measures how the leg moves
in space with high
temporal resolution.
The high
temporal resolution tracks the evolution of structures
in great detail and correlates formation histories to the environments
in which the structures form.
«Young students of cognitive neuroscience are lucky to be
in the midst of a new era where we have access to amazing new tools of science for eavesdropping on the population of cells with a superb
temporal resolution,» Parvizi says.
Through analysis of high -
resolution anatomical magnetic resonance imaging of brain volumes, taken three times over the two - year study period, the researchers were able to determine that individuals with MCI or Alzheimer's showed greater losses
in gray matter volume
in both the basal forebrain and
temporal lobe, compared with cognitively normal controls.
At lower levels,
in the retina and
in the geniculate, cells
in these two subdivisions differ
in their color selectivity, contrast sensitivity,
temporal properties, and spatial
resolution.
In particular, electron pulse technology still has a long way to go to achieve the
temporal resolution required to capture the motions of electrons inside a material.
He feels he has landed
in an area with the right balance of variables, or, as he calls it, «a sweet spot of spatial and
temporal resolution.»
But Betzig says that
in terms of combined spatial
resolution and
temporal resolution, there is no technique like it.
Although non-invasive methods to explore brain function
in humans such as functional imaging and EEG / MEG have been informative regarding the potential role of a given brain area
in a particular cognitive function, they lack the necessary
temporal and spatial
resolution to study brain microcircuits.
We will use high and super-
resolution fluorescence microscopy like total internal reflection fluorescence microscopy (TIRFM) and fluorescence photo - activation localization microscopy (FPALM) to visualize and track the spatio -
temporal dynamics of tethering and SNARE proteins
in live and fixed cells with single molecule
resolution.
We aim at understanding molecular processes
in biological systems with a high spatio -
temporal resolution and with regard to uncertainties and scaling cascades by utilizing mathematical advances and efficient HPC techniques.
The current project will use high -
resolution mass spectrometry - based metabolomics approaches to measure
temporal and spatial changes of metabolic pathways
in the RPE and retina under both physiological and disease conditions, with a focus on mTOR - mediated signal transduction pathways.
Conditional expression of hairpin constructs
in Drosophila is a powerful method to disrupt the activity of single genes with a spatial and
temporal resolution that is impossible, or exceedingly difficult, using classical genetic methods.
Prior to Joining IDRI, Matthew worked at the Institut de Biologie Integrative de la Cellule, France with Dr. Frederic Boccard applying super
resolution microscopy to study the
temporal and spatial localization of proteins involved
in bacterial chromosome organization.
Objective: To study, at high spatial and
temporal resolution, the conformational dynamics of the nicotinic receptors enabling neuronal communication
in the brain, which are major therapeutic targets linked to cognition and tobacco dependence.
Samples for analyses were taken every two hours
in order to obtain a high
temporal resolution.
In order to draw arbitrarily - chosen ChR2 stimulation patterns with sub-millisecond
temporal resolution, the macroscope was implemented with a random - access scanning head based on acousto - optic deflectors (AODs).
In addition to 2 - photon microscopy, lightsheet microscopy is rapidly becoming the preferred technique for many of these samples due to its fast
temporal resolution and decreased phototoxicity.
In order to address the challenges of future ocean acidification at a regional scale, it is necessary to increase the
resolution of spatial and
temporal monitoring of the inorganic carbon system beyond what is currently available.
However some technical challenges still need to be taken to make the technology more accessible and usable to its full potential: gaining selective and comprehensive genetic access to the neurons of interest, controlling variation
in the expression of the optogenetic tools (when using viruses) and its precise localization (axon vs. presynaptic terminals), tailoring light - delivery system signals to individual cells
in a population rather than the population as a whole, developing observation techniques which have the same spatial and
temporal resolution as those tools... to cite only a few of them.
In vivo mapping of brain activity is implemented via calcium imaging techniques at high
temporal resolution.
One approach is to develop empirical regional models that enable aragonite saturation state to be estimated from existing hydrographic measurements, for which greater spatial coverage and longer time series exist
in addition to higher spatial and
temporal resolution.
We use the Haplobank
in reverse genetic screens to investigate the
temporal resolution of essential genes
in mES cells, and to identify novel genes that control sprouting angiogenesis and lineage specification of blood vessels.
«This money will help us develop completely new optical methods to study dynamics
in the living cell at very high spatial and
temporal resolution.»
Watch the video with Dr. Kirk McManus, Associate Professor, University of Manitoba, and Senior Scientist, CancerCare Manitoba, to learn how
temporal resolution of 3D tumor spheroids
in colorectal cancer is obtained using the Cytation microplate reader by BioTek.
«
In multiplayer mode, however, we use a technique called «
temporal reprojection,» which combines pixels and motion vectors from multiple lower -
resolution frames to reconstruct a full 1080p image.
In reducing per - frame render time to 1 / 60th of a second - 16.7 ms - dynamic resolution scaling along with temporal reconstruction plays a key role in accelerating the render pipeline, and this can introduce a combination of softness and some dithering artefacts, with the extent changing on a per - platform basi
In reducing per - frame render time to 1 / 60th of a second - 16.7 ms - dynamic
resolution scaling along with
temporal reconstruction plays a key role
in accelerating the render pipeline, and this can introduce a combination of softness and some dithering artefacts, with the extent changing on a per - platform basi
in accelerating the render pipeline, and this can introduce a combination of softness and some dithering artefacts, with the extent changing on a per - platform basis.
Interestingly, both versions of the game use
Temporal Reconstruction but only when dynamic
resolution kicks
in.
While Horizon is a 30 fps title, the additional
temporal resolution makes frame - rate analysis with accurate frame - time graphing possible, giving us our first work -
in - progress look at how Guerrilla's beautiful title is shaping up on the new PlayStation 4 hardware.
Having worked closely with Ubisoft throughout Watch Dogs 2's development, we've had the opportunity to integrate HBAO + for richer, more realistic Ambient Occlusion contact shadowing; PCSS and HFTS for vastly improved character, object and world shadowing; TXAA for improved anti-aliasing and the addition of
temporal anti-aliasing; SLI for increased performance on Multi-GPU systems; Surround for immersive triple - screen gaming; and NVIDIA Ansel, an
in - game tool that enables you to capture unique screenshots
in Super
Resolution, Stereo, 360 ° Virtual Reality, and 360 ° Stereo formats.
By analyzing 80 proxy records from around the globe (generally with
resolutions better than 500 years) the authors are able to evaluate the changes occurring during different time periods
in order to characterize the spatial and
temporal structure of the deglacial evolution.
Indeed, the paleoclimate community, with help from the various funding agencies, e.g. NSF, NOAA, etc., is actively engaged
in work that should extend our knowledge at the relevant
temporal resolutions (i.e. decadal) several millennia back
in time.
Our study did not directly address this question because the paleotemperature records used
in our study have a
temporal resolution of ~ 120 years on average, which precludes us from examining variations
in rates of change occurring within a century.
There's
temporal resolution loss as you go back, but I suspect that for a given background climate, there's a lot of «boringness» within it (e.g., how much
in - Eocene or
in - Snowball variability do we actually expect?
This product is consistent with broad current knowledge about the surface sources and sinks of CO2, CH4 and N2O, but, to our knowledge, it is unique
in its combination of
temporal coverage, spatial
resolution and inclusion of recent measurements.