Sentences with phrase «term effects of the product»

«The problem with routine prescription of prenatal Rhogam is that many babies who are Rh negative like their mothers will be exposed to the drug, and there has been no systematic study of the long - term effects of this product in babies.

I could not find alot of information on it, but most people were saying that we don't know the long term effects of the product.

It takes responsibility for the short - and long - term effects of its products.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

Such risks, uncertainties and other factors include, without limitation: (1) the effect of economic conditions in the industries and markets in which United Technologies and Rockwell Collins operate in the U.S. and globally and any changes therein, including financial market conditions, fluctuations in commodity prices, interest rates and foreign currency exchange rates, levels of end market demand in construction and in both the commercial and defense segments of the aerospace industry, levels of air travel, financial condition of commercial airlines, the impact of weather conditions and natural disasters and the financial condition of our customers and suppliers; (2) challenges in the development, production, delivery, support, performance and realization of the anticipated benefits of advanced technologies and new products and services; (3) the scope, nature, impact or timing of acquisition and divestiture or restructuring activity, including the pending acquisition of Rockwell Collins, including among other things integration of acquired businesses into United Technologies» existing businesses and realization of synergies and opportunities for growth and innovation; (4) future timing and levels of indebtedness, including indebtedness expected to be incurred by United Technologies in connection with the pending Rockwell Collins acquisition, and capital spending and research and development spending, including in connection with the pending Rockwell Collins acquisition; (5) future availability of credit and factors that may affect such availability, including credit market conditions and our capital structure; (6) the timing and scope of future repurchases of United Technologies» common stock, which may be suspended at any time due to various factors, including market conditions and the level of other investing activities and uses of cash, including in connection with the proposed acquisition of Rockwell; (7) delays and disruption in delivery of materials and services from suppliers; (8) company and customer - directed cost reduction efforts and restructuring costs and savings and other consequences thereof; (9) new business and investment opportunities; (10) our ability to realize the intended benefits of organizational changes; (11) the anticipated benefits of diversification and balance of operations across product lines, regions and industries; (12) the outcome of legal proceedings, investigations and other contingencies; (13) pension plan assumptions and future contributions; (14) the impact of the negotiation of collective bargaining agreements and labor disputes; (15) the effect of changes in political conditions in the U.S. and other countries in which United Technologies and Rockwell Collins operate, including the effect of changes in U.S. trade policies or the U.K.'s pending withdrawal from the EU, on general market conditions, global trade policies and currency exchange rates in the near term and beyond; (16) the effect of changes in tax (including U.S. tax reform enacted on December 22, 2017, which is commonly referred to as the Tax Cuts and Jobs Act of 2017), environmental, regulatory (including among other things import / export) and other laws and regulations in the U.S. and other countries in which United Technologies and Rockwell Collins operate; (17) the ability of United Technologies and Rockwell Collins to receive the required regulatory approvals (and the risk that such approvals may result in the imposition of conditions that could adversely affect the combined company or the expected benefits of the merger) and to satisfy the other conditions to the closing of the pending acquisition on a timely basis or at all; (18) the occurrence of events that may give rise to a right of one or both of United Technologies or Rockwell Collins to terminate the merger agreement, including in circumstances that might require Rockwell Collins to pay a termination fee of $ 695 million to United Technologies or $ 50 million of expense reimbursement; (19) negative effects of the announcement or the completion of the merger on the market price of United Technologies» and / or Rockwell Collins» common stock and / or on their respective financial performance; (20) risks related to Rockwell Collins and United Technologies being restricted in their operation of their businesses while the merger agreement is in effect; (21) risks relating to the value of the United Technologies» shares to be issued in connection with the pending Rockwell acquisition, significant merger costs and / or unknown liabilities; (22) risks associated with third party contracts containing consent and / or other provisions that may be triggered by the Rockwell merger agreement; (23) risks associated with merger - related litigation or appraisal proceedings; and (24) the ability of United Technologies and Rockwell Collins, or the combined company, to retain and hire key personnel.

The idea of meddling with something as fundamental to our existence as food can be unnerving, and the long - term health and environmental effects of the products will not be known for quite some time.

, this sort of effect is disastrous for businesses that depend on customers deriving long - term value (productivity, convenience, etc.) from their product (s).

Having your business become a brand name for a particular product or service is immeasurable in terms of the effect on your business — in effect, without the expenditure of any effort or costs, your product sells itself in the marketplace.

If there is a competitive drug market, with limited advantage offered by the new drug in terms of increased effectiveness or reduced side effects, the drug will probably not win substantial market share in its product category.

Irrespective of the short - term effects, Osram has chosen the right strategy, under which it is focusing on semiconductor - based high - tech products.

«The term implies that the products could go live again, but I'm thinking we'll never see those products again,» laments one registered rep who had had been putting a lot of business through one of the companies with suspensions now in effect.

Last year, a report by the Oxford Martin School at Oxford University, led by Professor Marco Springmann, said a tax on animal products could have a «substantial» effect in terms of mitigating their contributions to climate change.

The opportunities for Australia are immense not just in terms of the potential benefit to the Australian economy through future jobs and export earners, but also because Australians will benefit from better and more cost - effective health products and services as a flow on effect from a thriving domestic MTP industry.

The weight loss effects of such fad diets or products, which claim to be «miracle diets», have short term results and have many side effects.

Changing the ratio of water and formula changes the composition of the product, which could have severe short and long - term effects on your child's health and development.

Additionally, there have been very few, if any, studies done on the long - term effects of some of these products.

This sets the standard for the term Natural and stipulates: * Product must be made up of at least 95 percent truly natural ingredients or ingredients that are derived from natural sources * No ingredients with any potential suspected human health risks * No processes that significantly or adversely alter the purity / effect of the natural ingredients * Ingredients that come from a purposeful, renewable / plentiful source found in nature (flora, fauna, mineral) * Processes that are minimal and don't use synthetic / harsh chemicals or otherwise dilute purity * Non-natural ingredients only when viable natural alternative ingredient are unavailable and only when there are absolutely no suspected potential human health risks

While all of these products have «equivalent success in appropriately trained hands,» the researchers note that they are not interchangeable in terms of dosage and effects.

Tattersall explains how epigenetic effects on key genes cascade to produce radical morphological changes in an eye blink, and why our unusual thinking style, far from being the perfected product of long - term selective pressures, was bootstrapped out of existing abilities barely 100,000 years ago.

«We hypothesized that long - term yogurt intake might reduce the risk of cardiovascular problems since some previous small studies had shown beneficial effects of fermented dairy products,» said one of the paper's authors, Justin Buendia.

«While genetic modification of crops can introduce new beneficial traits into existing crops, the resulting products need to be tested for long - term health effects before making assumptions about their impact on human health,» said senior investigator Frances Sladek, a professor of cell biology and neuroscience at UC Riverside.

I am very pleased with the product performance so far and have high hopes for positive long - term effects with continued use, of

Most of these parameters are related to the changes occurring within the dermal matrix, which improved after treatment, whereas most of the topically applied cosmetic products have a short term effect on superficial structures.

We recently published an article documenting the grim long - term effects of low - carbohydrate diets, in which we explain the evidence - based research showing that low - carbohydrate diets high in fat and protein including meat, dairy products, eggs, fish, and oil actually worsen diabetes health, increase cancer risk, increase cholesterol, increase atherosclerosis, harden blood vessels, and increase all - cause mortality.

It is unfortunate that the damaging effects of these chemical laden products are hidden from us over the short term.

Hello Kmatthews, one must look at the long term effects and side effects of any drugs or supplements before claiming a product completely helpful due to a simple lowering of lipid profiles.

Cysteine helps protect the liver against long - term effects of alcohol use, specifically from the poison acetaldehyde (a by - product of alcohol metabolism), although it does not reduce drunkenness.

And while the long - term effects of GMO products are not really known, there are studies that show that GMO anti-nutrients can be destructive to health and have a negative impact on gene expression.

This study was the first of its kind to look at the long - term effects of cleaning products on the respiratory tract.

Risks and uncertainties include without limitation the effect of competitive and economic factors, and the Company's reaction to those factors, on consumer and business buying decisions with respect to the Company's products; continued competitive pressures in the marketplace; the ability of the Company to deliver to the marketplace and stimulate customer demand for new programs, products, and technological innovations on a timely basis; the effect that product introductions and transitions, changes in product pricing or mix, and / or increases in component costs could have on the Company's gross margin; the inventory risk associated with the Company's need to order or commit to order product components in advance of customer orders; the continued availability on acceptable terms, or at all, of certain components and services essential to the Company's business currently obtained by the Company from sole or limited sources; the effect that the Company's dependency on manufacturing and logistics services provided by third parties may have on the quality, quantity or cost of products manufactured or services rendered; risks associated with the Company's international operations; the Company's reliance on third - party intellectual property and digital content; the potential impact of a finding that the Company has infringed on the intellectual property rights of others; the Company's dependency on the performance of distributors, carriers and other resellers of the Company's products; the effect that product and service quality problems could have on the Company's sales and operating profits; the continued service and availability of key executives and employees; war, terrorism, public health issues, natural disasters, and other circumstances that could disrupt supply, delivery, or demand of products; and unfavorable results of other legal proceedings.

The inverse funds exhibit the same traits as the leveraged funds in terms of compounding and rebalancing, but those effects are muted because of the low gearing in the products.

The Dividend Rate and Annual Percentage Yield are fixed and will be in effect for the initial term of the account so long as the required products and services applicable to the relationship levels are maintained.

In both instances, these services or products may include: company financial data and economic data (e.g., unemployment, inflation rates and GDP figures), stock quotes, last sale prices and trading volumes, research reports analyzing the performance of a particular company or stock, narrowly distributed trade magazines or technical journals covering specific industries, products, or issuers, seminars or conferences registration fees which provide substantive content relating to eligible research, quantitative analytical software and software that provides analyses of securities portfolios, trading strategies and pre / post trade analytics, discussions with research analysts or meetings with corporate executives which provide a means of obtaining oral advice on securities, markets or particular issuers, short - term custody related to effecting particular transactions and clearance and settlement of those trades, lines between the broker - dealer and order management systems operated by a third party vendor, dedicated lines between the broker - dealer and the investment adviser's order management system, dedicated lines providing direct dial - up service between the investment adviser and the trading desk at the broker - dealer, message services used to transmit orders to broker - dealers for execution, electronic communication of allocation instructions between institutions and broker - dealers, comparison services required by the SEC or another regulator (e.g., use of electronic confirmation and affirmation of institutional trades), exchange of messages among broker - dealers, custodians, and institutions related to a trade, post-trade matching of trade information, routing settlement instructions to custodian banks and broker - dealers» clearing agents, software that provides algorithmic trading strategies, and trading software operated by a broker - dealer to route orders to market centers or direct market access systems.

In both instances, these services or products may include: company financial data and economic data (e.g., unemployment, inflation rates and GDP figures), stock quotes, last sale prices and trading volumes, research reports analyzing the performance of a particular company or stock, narrowly distributed trade magazines or technical journals covering specific industries, products, or issuers, seminars or conferences registration fees which provide substantive content relating to eligible research, quantitative analytical software and software that provides analyses of securities portfolios, trading strategies and pre / post trade analytics, discussions with research analysts or meetings with corporate executives which provide a means of obtaining oral advice on securities, markets or particular issuers, short - term custody related to effecting particular transactions and clearance and settlement of those trades, lines between the broker - dealer and order management systems operated by a third party vendor, dedicated lines between the broker - dealer and the investment adviser's order management system, dedicated lines providing direct

Vomiting, diarrhea, loss of appetite, facial swelling Joint inflammation (arthritis, fever, muscle soreness), especially in Dobermans Skin rashes and itchiness Liver failure (nausea; yellowing of gums, skin, eyes) Inability to produce adequate tears or «dry eye» (increased blinking or discharge, eye rubbing) Sulfa bladder or kidney stones Blood abnormalities (bleeding tendencies, pale gums, fatigue, or fever of 103 - 105 ° F) Dogs can develop hypothyroidism with long - term use It is important to stop therapy and contact your veterinarian immediately if you think you pet has a medical problem or side effect from this product's therapy Can this drug be given with other drugs?

There are questions about the effects of long - term, cumulative exposures as well as combined exposures from the use of other products containing OPs and carbamates.

PB: Another concern often sparked by such a merger is what effect the new partnership will have on the product in terms of quality, ingredients and sourcing.

BioActive is the use of biologically active compounds in the product and is also a term used in veterinary research, referring to the compounds that have an effect on cells and tissues — examples include fatty acids, flavonoids, choline, prebiotics and polyphenols.

The most common recalls are issued for things like elevated levels of beef thyroid hormone, which may only have a short term effect that is reversed once the dog stops eating that product.

Mapping the long - term effects of the nearly 2 million gallons of dispersant used by BP PLC may well be equally difficult, given the array of unanswered questions that surround the products» rapid breakdown of oil droplets and their chronic toxicity.

Unfortunately, mean temperatures have risen much further when account is taken of the short - term masking effect of aerosols emitted from coal and oil, mainly sulphur dioxide and its oxidized products... «Thus, according to -LSB-...]

But remember, the existing products include a compensation to try and remove UHI, UHI only impacts our long term temperature results if the magnitude of the effect is growing, and each station's data still has to be added to the results for all other stations using Area Weighted Averaging.

While climate effects are often measured in terms of its financial impacts on countries» Gross Domestic Product, that doesn't capture the full human cost, says report author Stéphane Hallegatte, a World Bank senior economist.

Nanoparticles are found in lots of products we use but are still so new that there is not enough research yet on the long - term health effects.

Over the years, however, the drug companies have found ways of rushing their products to retail shelves without understanding their full and long term effects.

The pharmaceutical industry has the benefit of resources, the insider knowledge of the product, and the profit motive that make it possible to game the system and market drugs whose long term side effects may not be fully understood.

Huntsman v Petroplus: multi-million dollar dispute under an agreement for the supply of naphtha and LPG raising issues of construction (including whether the effect of an entire agreement clause is to exclude implied terms under the Sale of Goods Act 1979) and technical questions as to the cause of mercury contamination and whether it was such as to render the products unsatisfactory or unfit for purpose).

While many children suffer meconium aspiration at birth with few long - term effects, some will develop meconium aspiration syndrome (MAS) as a result of breathing in the waste products they excreted in the womb.

Huntsman v Petroplus - multi-million dollar dispute under an agreement for the supply of naphtha and LPG raising issues of construction (including whether the effect of an entire agreement clause is to exclude implied terms under the Sale of Goods Act 1979) and technical questions as to the cause of mercury contamination and whether it was such as to render the products unsatisfactory or unfit for purpose).

Product Basics TotalSecure + is a pure term insurance plan with no maturity benefits - in effect, the best kind of insurance plan.