Sentences with phrase «term effects on disease»

«We focused on children because early exposure can have long - term effects on disease outcomes,» says Rainbow Vogt, lead author of the study.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

For its annual list, US News & World Report ranked 38 eating plans, considering different criteria including how easy the diet is to follow, its effects on weight loss (both short and long term), how nutritional and safe the diet is, and how well it helps prevent diabetes and heart disease.

«Hitler was not insane or deranged, or suffering from drug - induced delusions,» he writes, «or laboring under the effects of some chronic disease such as syphilis, or acting in an unresolved hypnotic trance: on the contrary, he was sane according to any reasonable definition of the term, and fully responsible for his actions.»

Actually, since cancer is a disease of old age, which kicks in long after most people have done whatever procreating they're going to do, it has zero effect on long - term survivability of the species.

In cases of true gluten sensitivity or celiac disease, ingesting even a trace amount can have serious detrimental effects on your health in both the short and long terms.

Although breastfeeding has modest effects on blood pressure (51) and adiposity (52, 53) in later life, it has numerous other health benefits, including protection against infectious disease morbidity (54) and mortality (55) in infancy and a lower risk of type 2 diabetes (56) and improved neural and psychosocial development in the longer term (57, 58).

However, there is still limited data on the short and long - term effects of administering stem cell therapy in chronic respiratory disease.

«Healthy gut bacterial communities are known to benefit immune regulation, metabolism and potentially even the nervous system, so if cholera or other diarrheal diseases permanently impact the microbiota, there could be long - term effects on human health,» explains Regina LaRocque, MD, MPH, of the Massachusetts General Hospital (MGH) Division of Infectious Diseases, co-senior author of the paper.

«Stroke damages blood - spinal cord barrier, researchers find: Stroke's long - term effects on blood - spinal cord barrier can lead to «an increasingly toxic environment» in spinal cord and «significant input on disease pathology».»

Williams said, the long - term follow up allowed authors to examine dietary patterns and analyze the effect of gradual adherence to a plant - based diet through reduced animal food intake and increased plant food intake on heart disease risk.

This coupling, termed O - GlcNAcylation, has favorable effects on disease - injured cells, including myocytes.

«The introduction of mitochondria into damaged cells has beneficial effects on the health of cells and, in the long term, we believe that mesenchymal stem cells could even be engineered to create more effective therapies for lung disease in humans.»

«More studies are required in order to make these important associations in terms of the effects of supplementation on cardiometabolic syndrome, the immune and inflammatory mechanisms of cardiovascular disease in postmenopausal women, and their quality of life,» Nahas said.

«Our goal is to define readily implementable and sustainable lifestyle changes that will have a long - term effect on the course of the disease.

However, the long - term effects of e-cigarettes on liver disease, diabetes, heart disease or stroke are unknown.

This study — only the second overall assessment of diet and food on this disease — provides a very thorough evaluation of current scientific knowledge and makes a point of only reporting dietary interventions and specific foods that clearly show proven long - term effects.

Therefore, a lack of testosterone is not only a serious obstacle on your road to great muscles — if left untreated, low testosterone levels can have grave long - term negative effects on your health, ranging from osteoporosis and diabetes to an increased risk of death from heart disease.

According to older beliefs dietary cholesterol is the cause of heart disease and other health problems, but recent studies have shown that dietary cholesterol has a low and short - term effect on blood cholesterol.

His team is also studying the long - term effects of gluten consumption on other health measures, including heart disease and weight gain.

Most recently, a study which examined the effects of this type of training on the metabolic constraints of fatty liver disease found that 12 weeks of training significantly reduced the levels of fat, iron and insulin in the subjects, thereby alleviating the symptoms of metabolic syndrome in terms of a non-alcoholic fatty liver disease.

Dr. Tom O'Bryan discusses gluten sensitivity, celiac disease, and the long term effects of grain consumption on the Wellness Mama Podcast.

«Diet has tremendous effects on our short - and long - term health, especially when it comes to obesity, diabetes, and heart disease,» says Dariush Mozaffarian, MD, associate professor of cardiovascular medicine at Harvard Medical School.

Controlling flare - ups of eczema symptoms may help reduce the risk of problems such as sleep disturbance, but heart disease and other conditions may develop due to eczema's long - term effects on the body, Silverberg said.

Diabetes is a seriously debilitating disease that has many long - term effects you wouldn't wish on your enemies... why suffer these effects when you can reverse and even rid yourself of most, if not all, of them.

The long term health benefits of fruit / honey / nectar have been proven and the burden of proof is on you to show fruit has long term disease effects.

Cook NR, «Long term effect of dietary sodium reduction on cardiovascular disease outcomes: observational follow - up of the trials of hypertension prevention.

And such data as there is (on the long term effects) suggests that low carb increases risk of cardiovascular disease, and accelerates mortality.

This disease has long - term effects on the joints and tendons and, if not treated, can lead to heart and kidney disease and other major problems.

However, long - term studies on the effects of fluoride are showing that it can cause a multitude of health issues including cancer (specifically bladder), gum disease, thyroid dysfunction, kidney and liver disease, genetic defects, endocrine imbalance, nervous system disorders and bone disease including fluorosis.

So, «[E] arly dietary counseling of teenage acne patients is thus a great opportunity for dermatology, which will not only help to improve acne but may reduce the long - term adverse effects of Western diet on more serious [TOR]- driven diseases...»

1935 Effects of the high carbohydrate - low calorie diet upon carbohydrate tolerance in diabetes mellitus 1955 Low - fat diet and therapeutic doses of insulin in diabetes mellitus 1958 Effect of rice diet on diabetes mellitus associated with vascular disease 1976 Beneficial effects of a high carbohydrate, high fiber diet on hyperglycemic diabetic men 1977 Effect of carbohydrate restriction and high carbohydrates diets on men with chemical diabetes 1979 High - carbohydrate, high - fiber diets for insulin - treated men with diabetes mellitus 1981 High carbohydrate high in fibre diet in diabetes 1982 Response of non-insulin-dependent diabetic patients to an intensive program of diet and exercise 1983 Long - term use of a high - complex - carbohydrate, high - fiber, low - fat diet and exercise in the treatment of NIDDM patients 1994 Diet and exercise in the treatment of NIDDM: the need for early emphasis 1999 Toward improved management of NIDDM: A randomized, controlled, pilot intervention using a lowfat, vegetarian diet 2005 The effects of a low - fat, plant - based dietary intervention on body weight, metabolism, and insulin sensitivity 2006 A low - fat vegan diet improves glycemic control and cardiovascular risk factors in a randomized clinical trial in individuals with type 2 diabetes 2006 Effect of short ‐ term Pritikin diet therapy on the metabolic syndrome 2009 A low - fat vegan diet and a conventional diabetes diet in the treatment of type 2 diabetes: a randomized, controlled, 74 - wk clinical trial

A diet rich in sweets has both short - and long - term effects on your well - being, and can lead to disease.

Dietary interventions must be implemented to promote sustained beneficial effects on disease markers and long - term adherence.

King LK, Almeida QJ, Ahonen H. «Short - term effects of vibration therapy on motor impairments in Parkinson's disease.»

Although low - carb diets have become popular for managing type 2 diabetes, few high - quality studies have investigated their long - term effects on blood sugar control and risk factors for heart disease (2).

Short term effects of energy restriction and dietary fat sub-type on weight loss and disease risk factors

The past doubts regarding the effects of using a ketogenic diet long term as one's main diet were centered on the «official» advice to avoid saturated fats because they supposedly raised cholesterol levels, which they claim increases the risk of cardiovascular heart disease.

This study shows in terms of having this enormous effect on risk of disease and actually about a 38 percent decrease in the risk of obesity.

Some diseases have a direct impact on a child's growth and development, and early detection is the key to addressing these problems before they can have a long - term effect.

â $ cents Conduct long - term studies on the effects of both viscous and whole - grain cereal fibers on coronary heart disease and diabetes risk factors.

This compelling knowledge base underscores three significant, unmet needs: (1) valid and reliable biological and bio-behavioral measures (or «biomarkers») of «toxic stress» to identify children who are at higher risk of chronic disease in adulthood; (2) more effective intervention strategies to prevent, reduce, or mitigate the long - term health consequences of significant adversity in early childhood; and (3) biomarkers that are sensitive to change and can thus be used to assess the short - term and medium - term effects of intervention strategies whose ultimate impacts on physical and mental health may not be apparent until decades later.

The study examines epidemiology and the long - term effects of nutrition, environment, lifestyle and genetics on health and the development of cancer and other major diseases in dogs.

GALT tests for and treats tick - borne diseases like Ehrlichia, Babesia, Rocky Mountain Spotted Fever, and Lyme disease because they can have long - term effects on your greyhound's health.

Tumulty JW, Broussard JD, Steiner JM, Peterson ME, Williams DA: Clinical effects of short - term oral budesonide on the hypothalamic - pituitary - adrenal axis in dogs with inflammatory bowel disease.

You have to factor in long - term sustainability, requirements to manufacture it on the large scale, the effects on disease spread, whether or not it's even reasonably possible with how things are at current, and even such lovely things as Hurricane Dolly.