For this study, the team will
test Sofosbuvir, a new drug, and Ribavirin, which is used in the treatment with interferon.
Not exact matches
In subsequent
tests using an immunodeficient mouse model infected by Zika, intravenous injections of
sofosbuvir significantly reduced viral loads in blood serum compared to a placebo group.
In
tests using human neural progenitor cells (NPCs)-- self - renewing, multipotent cells that generate neurons and other brain cell types — the scientists found that exposure to
sofosbuvir not only rescued dying NPCs infected with the Zika virus, but restored gene expression linked to their antiviral response.