Sentences with phrase «test cells used»

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Chicago, GenomeWeb — A new study by researchers from Memorial Sloan Kettering Cancer Center has demonstrated the predictive power of an AR - V7 protein expression test using Epic Sciences» non-EPCAM-based circulating tumor cell detection platform, which could help guide treatment decisions for men with metastatic castration - resistant prostate cancer.
The United Nations Development Programme (UNDP) is planning a pilot project to test a system that allows individuals to invest in solar energy - generating cells and effectively receive rent from consumers that use the hardware.
Currently marketed for research use by Biofluidica, the test's microfluidic channels use specific cancer antibodies to detect capture circulating tumor cells.
This includes a stem cell research centre, a network of drug discovery institutes and a # 20 million global clinical development fund dedicated to supporting Phase I and II clinical trials; and a # 2 million collaboration between University of Cambridge and University College London that will use donated cells from people with Alzheimer's to test potential new treatments
Indeed, because eggs are large cells that are relatively easy to manipulate, they are one of the favored cell types used by biologists to express foreign genes and to test gene function.
Genetic screening using free fetal cells can be done, depending on the test, from 8 weeks on.
A ductogram or the Halo test may be used to examine breast fluid or ductal cells.
Cord blood stem cells can be used to treat dozens of diseases and are being tested in FDA - regulated clinical trials to help people with autism, brain injury, and other conditions.
Choose an obstetrician or health care provider Interview potential doctors Contact health insurance company about coverage Start and pregnancy and birth budget Discuss financial effects of pregnancy and baby with partner Stop smoking Stop drinking Stop using street drugs Talk to your physician about any prescription medications Drink at least 8 glasses of water every day Visit the doctor at least once per month or every 4 weeks Do not dye or perm hair Stop drinking coffee and other caffeinated beverages Exercise daily Start taking prenatal vitamins Eat foods rich in folic acid Eat iron rich foods Increase daily intake of whole grains, fruits and vegetables Nap as much as possible as fatigue is common Eat fish with low levels of mercury no more than 2 days per week Do not eat undercooked meats Do not eat unpasteurized dairy producs Do not eat cold cut deli meats Allow someone else to clean out the kitty litter, if applicable Limit exposure to chemicals Try to limit stress and tension Complete all prenatal tests — HIV, Chlamydia, Gonorrhea, Anemia, Blood Typing, Sickle Cell Anemia, Urine Screening and Rubella.
Embryos created through somatic cell nuclear transfer, which uses skin cells taken from the sick child, could also be used to test therapies.
As well as allowing the use of stem cells grown from established cell lines, the technology could enable the creation of improved human tissue models for drug testing and potentially even purpose - built replacement organs.
Researchers at the European Union Reference Laboratory for alternatives to animal testing developed five different tests that use human blood cells to detect contaminants in drugs that cause a potentially dangerous fever response.
Hingtgen's group is already testing how far their tumor - homing cells can migrate using larger animal models.
The researchers collected samples of indoor dust from 11 homes in North Carolina and tested extracts from the samples in a mouse pre-adipocyte cell model, 3T3 - L1 cells, often used to test compounds for potential effects on the accumulation of triglycerides, a type of fat.
The team designed DNA circuits that simultaneously test for 24 distinct regions of viral RNA — more than would have been possible using only naturally occurring DNA sequences (Cell, doi.org/wn4).
Immunophenotyping — a laboratory procedure used to study the proteins expressed by cells — is very commonly used in basic science research as well as in laboratory diagnostic testing.
«Because BX795 targets a common pathway that many viruses use to replicate inside the cell, it could be a new kind of broad - spectrum antiviral that might be used to treat other viral infections, including HSV - 2, which primarily affects the genitals, and HIV, although we have not yet tested it on viruses other than HSV - 1.»
Exposed to both air and fluid, the cells might also be used to model the lungs and test drugs for lung disease.
The researchers are beginning to use their model to test whether Zika virus, and other pathogens associated with congenital disease, can infect placental cells and / or cross the placental barrier.
First, the trial tested GM - CSFs which act on more than one blood cell lineage and are not commonly used nowadays.
A group in Japan hopes to test a similar approach in humans using stem cells from reprogrammed adult cells within the next three years.
To start, she used a cotton swab to get a sample of cells from her cheek, boiled them in a test tube in her kitchen to free the DNA, then added primers, nucleic acids that mark the part of the sequence.
Also, each was tested on a companion cell line already multi-drug resistant, as if the patient already had undergone chemotherapy using Paclitaxel.
Anand and his colleague Susan McKay started with human skin cells, which they turned into induced pluripotent stem cells (iPSCs) using a tried - and - tested method.
Researchers then tested cell cultures and mouse models by using a gene editing process called CRISPR - Cas9 to demonstrate how the presence or absence of myomaker and myomerger — both individually and in unison — affect cell fusion and muscle formation.
«We came up with a list of potential cellular candidates that could be compensating for the loss of these specific macrophages and used several different tests to determine which cells were clearing away the nerve debris after injury,» Lindborg said.
Each of the four compounds was then tested in the lab to see how it would affect a line of prostate cancer cells relatively sensitive to the chemotherapeutic Paclitaxel, commonly used to treat prostate cancer patients.
The lab tracked the differentiating process using fluorescent cell imaging, which tested for the necessary markers during each step.
The system works just like a standard glucose meter: patients test their blood using a traditional lancet, then use a special strip stored in the cell phone to analyze it.
The so - called STEP trial, sponsored by pharmaceutical giant Merck & Co. and the federally funded HIV Vaccine Trials Network (HVTN), was the first to test the idea of stimulating the immune system's killer T cells to hunt for the virus more aggressively, in this case using a weakened form of the cold virus to carry three genes from HIV.
A «Trojan horse» treatment for an aggressive form of brain cancer, which involves using tiny nanoparticles of gold to kill tumour cells, has been successfully tested by scientists.
In addition, the substance used to stick cells together (ViaGlue), will provide researchers with tools to create and test 3D in vitro cardiac tissue in their own labs to study heart disease and issues with transplantation.
Using frozen samples of Nannochloropsis oculata, a type of single - celled ocean - dwelling algae, Dina Pasini (University of Kent) set out to test the conditions which early life would have had to survive if it did indeed travel through space.
Roughly half of the 2,000 molecules tested include FDA - approved molecules used to prevent viral replication in infected cells.
Normally, the cells Nobel used for the test would divide and give rise to a specialized type of cell in the central nervous system called an oligodendrocyte.
A technique that involves genetically engineering brain cells so that they fire in the presence of certain drugs has been used to treat epilepsy in rats, and it could soon be tested in humans.
Hoping to develop a more potent approach, medical oncologist Ron Levy of Stanford University in Palo Alto, California, and colleagues used mice to test the cancer - fighting capabilities of some 20 molecules, including several types of antibodies that activate immune cells.
The enzyme was tested in three different cell lineages: leukemia cells incapable of producing asparagine at normal levels (MOLT4); another line of leukemia cells, in this case capable of producing asparagine at normal levels (REH); and non-malignant cells, used as a control (HUVECs).
Her new projects could eventually lead to light - based technologies used to improve drugs or to create new tests to find cancerous cells.
Researchers at The University of Texas MD Anderson Cancer Center developed a novel chimeric mouse model to test the combination therapy using immune checkpoint blockades with therapies targeting myeloid - derived suppressor cells (MDSCs).
To test that idea in the ragworm, Tomer used a technique he had developed to examine the complex brains of small creatures with unprecedented clarity: He created a high - resolution map of the worm's brain cells according to the genes they express, not just their shape and location.
BABY BLUE Using human eye cells, researchers fashioned an artificial eye surface that could be used to study and test treatments for eye diseases.
Using fluorescence inside living cells as well as biochemistry, they showed that SMN promotes an interaction between the «zipcode» region of a test RNA and a transport protein.
The materials that pharmaceutical companies use to test drugs» effects on cells don't allow for three - dimensional vascularization, a network of capillaries that carry drugs and other materials throughout the body.
Today, the lab's prenatal testing website stresses the use of «cell - free» fetal DNA, which passes across the placenta from fetal cells that have broken down.
Often times we'll use an animal model or cell culture model to test a bioactive to see if it has efficacy.
For his part, Collins, who has led NIH since 2009 and been kept on by the Trump administration, pointed to an array of promising NIH activities, including the development of new technologies to provide insights into human brain circuitry and function through the Brain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disease.
Using a diamond anvil pressure cell and laser heating — to duplicate the mantle's unimaginable pressure and heat — they tested their recipe of bridgmanite with a pinch of ferric iron.
Using tumor samples from a patient, they do lab tests to determine which substances can first make the different types of cancer cells uniform and then effectively kill them.
Cytology - based screening, known as the Pap test or Pap smear, is used to detect abnormal cells.
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