Not exact matches
Chicago, GenomeWeb — A new study by researchers from Memorial Sloan Kettering Cancer Center has demonstrated the predictive power of an AR - V7 protein expression
test using Epic Sciences» non-EPCAM-based circulating tumor
cell detection platform, which could help guide treatment decisions for men with metastatic castration - resistant prostate cancer.
The United Nations Development Programme (UNDP) is planning a pilot project to
test a system that allows individuals to invest in solar energy - generating
cells and effectively receive rent from consumers that
use the hardware.
Currently marketed for research
use by Biofluidica, the
test's microfluidic channels
use specific cancer antibodies to detect capture circulating tumor
cells.
This includes a stem
cell research centre, a network of drug discovery institutes and a # 20 million global clinical development fund dedicated to supporting Phase I and II clinical trials; and a # 2 million collaboration between University of Cambridge and University College London that will
use donated
cells from people with Alzheimer's to
test potential new treatments
Indeed, because eggs are large
cells that are relatively easy to manipulate, they are one of the favored
cell types
used by biologists to express foreign genes and to
test gene function.
Genetic screening
using free fetal
cells can be done, depending on the
test, from 8 weeks on.
A ductogram or the Halo
test may be
used to examine breast fluid or ductal
cells.
Cord blood stem
cells can be
used to treat dozens of diseases and are being
tested in FDA - regulated clinical trials to help people with autism, brain injury, and other conditions.
Choose an obstetrician or health care provider Interview potential doctors Contact health insurance company about coverage Start and pregnancy and birth budget Discuss financial effects of pregnancy and baby with partner Stop smoking Stop drinking Stop
using street drugs Talk to your physician about any prescription medications Drink at least 8 glasses of water every day Visit the doctor at least once per month or every 4 weeks Do not dye or perm hair Stop drinking coffee and other caffeinated beverages Exercise daily Start taking prenatal vitamins Eat foods rich in folic acid Eat iron rich foods Increase daily intake of whole grains, fruits and vegetables Nap as much as possible as fatigue is common Eat fish with low levels of mercury no more than 2 days per week Do not eat undercooked meats Do not eat unpasteurized dairy producs Do not eat cold cut deli meats Allow someone else to clean out the kitty litter, if applicable Limit exposure to chemicals Try to limit stress and tension Complete all prenatal
tests — HIV, Chlamydia, Gonorrhea, Anemia, Blood Typing, Sickle
Cell Anemia, Urine Screening and Rubella.
Embryos created through somatic
cell nuclear transfer, which
uses skin
cells taken from the sick child, could also be
used to
test therapies.
As well as allowing the
use of stem
cells grown from established
cell lines, the technology could enable the creation of improved human tissue models for drug
testing and potentially even purpose - built replacement organs.
Researchers at the European Union Reference Laboratory for alternatives to animal
testing developed five different
tests that
use human blood
cells to detect contaminants in drugs that cause a potentially dangerous fever response.
Hingtgen's group is already
testing how far their tumor - homing
cells can migrate
using larger animal models.
The researchers collected samples of indoor dust from 11 homes in North Carolina and
tested extracts from the samples in a mouse pre-adipocyte
cell model, 3T3 - L1
cells, often
used to
test compounds for potential effects on the accumulation of triglycerides, a type of fat.
The team designed DNA circuits that simultaneously
test for 24 distinct regions of viral RNA — more than would have been possible
using only naturally occurring DNA sequences (
Cell, doi.org/wn4).
Immunophenotyping — a laboratory procedure
used to study the proteins expressed by
cells — is very commonly
used in basic science research as well as in laboratory diagnostic
testing.
«Because BX795 targets a common pathway that many viruses
use to replicate inside the
cell, it could be a new kind of broad - spectrum antiviral that might be
used to treat other viral infections, including HSV - 2, which primarily affects the genitals, and HIV, although we have not yet
tested it on viruses other than HSV - 1.»
Exposed to both air and fluid, the
cells might also be
used to model the lungs and
test drugs for lung disease.
The researchers are beginning to
use their model to
test whether Zika virus, and other pathogens associated with congenital disease, can infect placental
cells and / or cross the placental barrier.
First, the trial
tested GM - CSFs which act on more than one blood
cell lineage and are not commonly
used nowadays.
A group in Japan hopes to
test a similar approach in humans
using stem
cells from reprogrammed adult
cells within the next three years.
To start, she
used a cotton swab to get a sample of
cells from her cheek, boiled them in a
test tube in her kitchen to free the DNA, then added primers, nucleic acids that mark the part of the sequence.
Also, each was
tested on a companion
cell line already multi-drug resistant, as if the patient already had undergone chemotherapy
using Paclitaxel.
Anand and his colleague Susan McKay started with human skin
cells, which they turned into induced pluripotent stem
cells (iPSCs)
using a tried - and -
tested method.
Researchers then
tested cell cultures and mouse models by
using a gene editing process called CRISPR - Cas9 to demonstrate how the presence or absence of myomaker and myomerger — both individually and in unison — affect
cell fusion and muscle formation.
«We came up with a list of potential cellular candidates that could be compensating for the loss of these specific macrophages and
used several different
tests to determine which
cells were clearing away the nerve debris after injury,» Lindborg said.
Each of the four compounds was then
tested in the lab to see how it would affect a line of prostate cancer
cells relatively sensitive to the chemotherapeutic Paclitaxel, commonly
used to treat prostate cancer patients.
The lab tracked the differentiating process
using fluorescent
cell imaging, which
tested for the necessary markers during each step.
The system works just like a standard glucose meter: patients
test their blood
using a traditional lancet, then
use a special strip stored in the
cell phone to analyze it.
The so - called STEP trial, sponsored by pharmaceutical giant Merck & Co. and the federally funded HIV Vaccine Trials Network (HVTN), was the first to
test the idea of stimulating the immune system's killer T
cells to hunt for the virus more aggressively, in this case
using a weakened form of the cold virus to carry three genes from HIV.
A «Trojan horse» treatment for an aggressive form of brain cancer, which involves
using tiny nanoparticles of gold to kill tumour
cells, has been successfully
tested by scientists.
In addition, the substance
used to stick
cells together (ViaGlue), will provide researchers with tools to create and
test 3D in vitro cardiac tissue in their own labs to study heart disease and issues with transplantation.
Using frozen samples of Nannochloropsis oculata, a type of single -
celled ocean - dwelling algae, Dina Pasini (University of Kent) set out to
test the conditions which early life would have had to survive if it did indeed travel through space.
Roughly half of the 2,000 molecules
tested include FDA - approved molecules
used to prevent viral replication in infected
cells.
Normally, the
cells Nobel
used for the
test would divide and give rise to a specialized type of
cell in the central nervous system called an oligodendrocyte.
A technique that involves genetically engineering brain
cells so that they fire in the presence of certain drugs has been
used to treat epilepsy in rats, and it could soon be
tested in humans.
Hoping to develop a more potent approach, medical oncologist Ron Levy of Stanford University in Palo Alto, California, and colleagues
used mice to
test the cancer - fighting capabilities of some 20 molecules, including several types of antibodies that activate immune
cells.
The enzyme was
tested in three different
cell lineages: leukemia
cells incapable of producing asparagine at normal levels (MOLT4); another line of leukemia
cells, in this case capable of producing asparagine at normal levels (REH); and non-malignant
cells,
used as a control (HUVECs).
Her new projects could eventually lead to light - based technologies
used to improve drugs or to create new
tests to find cancerous
cells.
Researchers at The University of Texas MD Anderson Cancer Center developed a novel chimeric mouse model to
test the combination therapy
using immune checkpoint blockades with therapies targeting myeloid - derived suppressor
cells (MDSCs).
To
test that idea in the ragworm, Tomer
used a technique he had developed to examine the complex brains of small creatures with unprecedented clarity: He created a high - resolution map of the worm's brain
cells according to the genes they express, not just their shape and location.
BABY BLUE
Using human eye
cells, researchers fashioned an artificial eye surface that could be
used to study and
test treatments for eye diseases.
Using fluorescence inside living
cells as well as biochemistry, they showed that SMN promotes an interaction between the «zipcode» region of a
test RNA and a transport protein.
The materials that pharmaceutical companies
use to
test drugs» effects on
cells don't allow for three - dimensional vascularization, a network of capillaries that carry drugs and other materials throughout the body.
Today, the lab's prenatal
testing website stresses the
use of «
cell - free» fetal DNA, which passes across the placenta from fetal
cells that have broken down.
Often times we'll
use an animal model or
cell culture model to
test a bioactive to see if it has efficacy.
For his part, Collins, who has led NIH since 2009 and been kept on by the Trump administration, pointed to an array of promising NIH activities, including the development of new technologies to provide insights into human brain circuitry and function through the Brain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the
use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and
test a «curative therapy» for the first molecular disease: sickle
cell disease.
Using a diamond anvil pressure
cell and laser heating — to duplicate the mantle's unimaginable pressure and heat — they
tested their recipe of bridgmanite with a pinch of ferric iron.
Using tumor samples from a patient, they do lab
tests to determine which substances can first make the different types of cancer
cells uniform and then effectively kill them.
Cytology - based screening, known as the Pap
test or Pap smear, is
used to detect abnormal
cells.