Not exact matches
Paweletz and his colleagues are now developing a PCR - based
test to detect drug resistance mutations in
lung tumors.
Potti and his colleagues began by
testing chemotherapy drugs on cultured cell lines from human
tumors, such as from the
lung, breast, or ovary.
To
test this idea, the researchers utilized two mouse models of human breast cancer metastasis and found dormant disseminated
tumor cells residing upon the membrane microvasculature of
lung, bone marrow and brain tissue.
They also
tested other cancer lines — human cervical,
lung and prostate cancers — and found that they responded to the patterned
tumor environments in the same way.
Various genetic
testing methods were used to examine
lung tumors, uninvolved
lung tissue and normal - appearing airways located varying distances from the
tumors.
«In our practice, we recommend that all patients with baseline EGFR T790M identified in their
lung tumor tissue be referred to clinical genetics to discuss EGFR T790M germline
testing.
The team is also hoping to
test T cells modified to attack breast,
lung, and colon
tumors.
The companies have launched a phase II trial of the antibody - drug conjugate, and are also
testing it in other solid
tumors, including ovarian and non — small - cell
lung cancers.
In the study, the researchers
tested phenformin as a chemotherapy agent in genetically - engineered mice lacking LKB1 and which had advanced stage
lung tumors.
Over the span of several months, the researchers recorded their results following
tests on the
lungs and the
tumors.
Initial evaluation of a dog with a suspected bone
tumor often includes: complete physical exam, blood
tests, radiographs (both the primary site and the
lungs), and a biopsy.