Sentences with phrase «tested at higher doses»

Other Alzheimer's drugs are also in development and being tested at higher doses.

Not exact matches

One moderate sacral insufficiency fracture occurred in one patient at the highest tested dose of 20 mg / kg every three weeks after 6 cycles.

The drug, daratumumab, proved generally safe in patients, even at the highest doses tested in the study.

The best immune response was shown in a group of nine test persons who received the highest dose of the vaccine three times at four - week intervals.

At the highest dose of DMAU tested, 400 mg, subjects showed «marked suppression» of levels of their testosterone and two hormones required for sperm production.

After receiving a booster dose at 40 months of age, 89 % -100 % of the children had high antibody levels for all but 1 of the 8 Meningitis B strains tested.

«If we can identify similar genetic loci in people, and if we could find biomarkers for these gene - environment interactions, then perhaps we could develop a simple blood test that identifies people who are at high risk of cancer from low - dose radiation,» says Mao.

At all post-immunization time points, mean log antibody levels (µg / mL) were significantly higher in the malaria vaccine groups compared to the rabies vaccine group (t - test p - values < 0.0001 at all post-immunization time points for each malaria vaccine dose group compared to rabies vaccine groupAt all post-immunization time points, mean log antibody levels (µg / mL) were significantly higher in the malaria vaccine groups compared to the rabies vaccine group (t - test p - values < 0.0001 at all post-immunization time points for each malaria vaccine dose group compared to rabies vaccine groupat all post-immunization time points for each malaria vaccine dose group compared to rabies vaccine group).

TIC10 seems to be nontoxic to normal cells or mice even at doses 10 times higher that an observed therapeutic dose, however more research needs to be completed to satisfy FDA requirements prior to initiation of clinical testing.

In a study at the Washington University School of Medicine in St. Louis, people who received high doses of the stress hormone cortisol daily for four days performed worse on recall tests than those in the control group.

Where traditional toxicology asserts that higher doses does greater harm, bisphenol A tests show that low doses can be the most toxic of all, partly because at low levels it can fall below the radar of your body's natural detox mechanism.

Then the researchers looked at the weight the test subjects could shift for just one leg press rep.. This time the low dose of Amplified Creatine worked a bit better than the creatine, and the high dose less.

But even the high dose at 25 mg / kg was only half the acceptable daily intake set by the FDA, so the FDA says one can safely consume 50 mg a day, but after just eight days on half that, participants had more irritable mood, exhibited more depression, and performed worse on certain brain function tests.

And numerous studies conducted to test the herbs» toxicity levels have shown that Tongkat Ali is safe to be consumed even at higher doses.

They opted for higher doses of pramlintide (240 ug TID [three times per day]-RRB- because in dose - escalation studies, the incidence and severity of adverse drug reactions was consistently low at all doses tested.

My new GP has done all sorts of tests and 90 % of my readings show withing the norm, the only thing he found is I have too high reverse T3, for which he prescribed slow release T3, even upped the dose to 20 mg a day with 100 mg of L thyroxin, and still, the T3 buggers are still at the end of the bracket over 500 I mean.

In another 3 - generation study no problem was found at 17.5 mg boron / kg / day, corresponding to 9 grams of borax / 60 kg while the next higher tested borax dose of 58.5 mg / kg / day, corresponding to 30 grams of borax / 60 kg, resulted in infertility.

The copay will likely be cheaper than an at - home test; plus, if you're really low, your doc can advise you on the appropriate dose to keep you in the normal range, which may be higher than what over-the-counter supplements provide.

In addition to English and math, the test - prep classes at Central High included a heavy dose of motivation.

Once the therapeutic dose for your pet is determined, phenobarbital blood levels and liver function tests will need to be monitored at least every six months to ensure that your pet's blood levels stay within the therapeutic range (i.e. that they do not get dangerously high or low), and that the no damage to the liver is occurring.

It might also help differentiate between PDH and AT, but that is better determined by the HDDS test (High Dose Dexamethasone Suppression test).