Sentences with phrase «tested human lung»

The researchers also tested human lung tissue of premature infants with BPD and found similar levels of increased autophagy.

Not exact matches

By printing multiple lung airways — or any other afflicted organ — from a human patient and testing drugs on them, pharma companies can bypass the ethically challenged practice of testing on animals and proceed to human clinical trials with greater confidence the drugs will actually work, according to Wadsworth.

Potti and his colleagues began by testing chemotherapy drugs on cultured cell lines from human tumors, such as from the lung, breast, or ovary.

In their latest study, they tested compounds against cells from nine different types of human cancer, including common types affecting blood, colon, breast, prostate, ovaries, kidneys, and lungs.

NIOSH immunotoxicologist Stacey Anderson has begun testing dicarbonyls, 4 - OPA in particular, to see if they provoke an immune reaction in mice or human lung cells.

Virologist Yoshihiro Kawaoka of the University of Wisconsin and University of Tokyo and his colleagues tested strains of H5N1 isolated from respiratory tissue in the noses, throats and lungs of infected humans.

Finally, a Calgary, Alberta — based company, Oncolytics Biotech, is testing a reovirus (an RNA virus often found in human lungs but thought to be nonpathogenic) against several types of cancer, including that of the lung and skin as well as head and neck malignancies.

First, the destabilizing effects of VX - 770 on the corrected CFTR protein might be less robust in the human body than were the effects seen in lab tests using human lung cells.

She expects she will find laminum - 8 uniquely overexpressed in other invasive cancers, like lung and colon cancer, but to date she has tested for it in only human brain and metastatic breast cancer.

To test this idea, the researchers utilized two mouse models of human breast cancer metastasis and found dormant disseminated tumor cells residing upon the membrane microvasculature of lung, bone marrow and brain tissue.

They also tested other cancer lines — human cervical, lung and prostate cancers — and found that they responded to the patterned tumor environments in the same way.

«We have also tested this process in human cells taken from diseased lung tissue, and we see very similar results.»

According to the team, further study is clearly needed, especially biotoxicity testing directly relevant to the human lung.

This week it emerged that the first human test of the controversial gene - editing technique CRISPR had taken place at West China Hospital in Chengdu, where oncologists used it to treat a man with an aggressive lung cancer.

Clevers and other scientists have developed organoids of the gut, liver, lung, brain, and many other human organs that can be used to model disease or to serve as test beds for drugs.

If the marriage of stem cells and CRISPR follows a similar path, it might not be long before pigs have enough Homo sapiens in them not only to grow human hearts, lungs, livers, and kidneys for transplant but also to model human diseases more closely than current lab animals do and to test experimental drugs.

After mroe than two years of testing on humans, the U.S. FDA has approved a new lung cancer pill for AstraZeneca, a British drugmaker.

Among these, Aflatoxin B1 (AFB1) causes extensive DNA damage and is the most potent carcinogen ever tested, especially affecting liver and lungs, also causing birth defects, immune - toxicity and even death in farm animals and humans.

The researchers conducted tests by growing both healthy human - lung cells and precancerous human - lung cells in laboratory flasks.