«In fact,
we tested known compounds and showed that two of them substantially reduced UBE3A activity in neurons.»
Not exact matches
By using products bearing the GREENGUARD Children & SchoolsSM or GREENGUARD Gold Certification mark, parents, teachers and school officials can rest easy
knowing these products have been independently
tested and verified to meet strict emission levels of pollutants, such as volatile organic
compounds (VOCs), formaldehyde and phthalates.
Who
knows, there may even be useful
compounds hidden away in alternative or traditional medicines that could be found through a good
testing program.
Instead of systematically
testing the effects of
known compounds — the pharmaceutical industry's basic model for more than a century — scientists can now investigate backward, combing through genomic data to find links between specific genotypes and diseases and then screening drug data to identify therapeutic candidates.
Thinking that high concentrations of the corrosive
NO might play a role in the nerve damage, Hilary Koprowski and his colleagues at Thomas Jefferson University in Philadelphia
tested in mice three
compounds — uric acid, PTIO, and D609 — that are
known to scavenge
NO or inhibit its production.
Among the substances they
tested was a synthetic, small - molecule
compound known as PF - 04554787.
In France, the Nosopharm researchers
tested the ODL
compounds against bacterial pathogens, including many
known to develop resistance.
The agency released data from these
test wells in November that confirmed high levels of carcinogenic chemicals such as benzene, and a chemical
compound called 2 Butoxyethanol, which is
known to be used in fracking.
To
test its model and lay the foundation for modeling increasingly complex material interactions, the team decided to simulate silicon dioxide (SiO2), a common, well - studied material, most well -
known as the
compound that forms quartz.
Because the team already
knew that nitric oxide and GAPDH were involved in the process, they
tested the ability of the
compound CGP3466B,
known to disrupt nitric oxide / GAPDH interactions, to halt cocaine - induced autophagy.
As far as we have
tested in these experiments, we found that the CDDO
compound had no
known side effects.
Knowing of America's desperate search for new antimalarial drugs (by then, the U.S. government and Winthrop scientists had screened roughly 14,000 candidate
compounds), French military doctors shipped samples back to the States for further
testing.
I said before that we hope to deliver this
compound as an eye drop, but for now we are
testing it as an injection into the eye because we
know that gets the
compound where it needs to be and that is how the existing drugs are delivered.
One method that is being
tested removes iron by means of a complex - forming
compound, or chelate,
known as EDMA (ethylenediiminobis (2 - hydroxy -4-methyl-phenyl) acetic acid).
«We
know these foods are beneficial to health, and the 10 - minute method we developed, which can
test for the presence of specific
compounds linked to these vegetables, will help researchers quantify exactly how much of these molecules are being consumed,» says Marcin Dyba, research associate at Georgetown Lombardi.
I
know a lot of
compounding people think you should
test salivary estrogen levels, but the normal level is so broad that it seems like a waste of money.»
A
compound known as ellagic acid has already put these properties to
test, and they may offer the clues the secret that lies behind red raspberries anti-cancer potency.
«My instinct is that it only makes sense to prevent children's exposure to chemicals
known to affect the nervous system, and those include pesticides, solvents, many volatile organic
compounds, metals, PCBs, and thousands of other poorly
tested synthetic chemicals now in commerce.
«After field
testing the modified silica, called Osorb, DOE's National Energy Technology Laboratory confirmed it can remove more than 99 percent of oil and grease from water, and more than 90 percent of benzene, toluene, ethylbenzene, and xylenes — also
known as BTEX — the volatile
compounds that can poison drinking water.»