Sentences with phrase «testing of the drug»

She plans shortly to begin animal testing of a drug derived from one of the three molecules.

Researchers hope to expand testing of the drug to more participants, including women and children, before it can be widely recommended as a new treatment.

Most animal testing of drugs has achieved between 10 % to 30 % less damage, and sometimes up to 50 %, she adds.

The mice described in the current report were developed for testing of drug and vaccine candidates and may not be good models for human transmission, said Weaver.

«Cyclodextrin therapy accelerates the hearing loss that is already a part of the natural progression of this disease,» said Ory, adding that the researchers expected to see hearing loss as a side effect, based on testing of the drug in animals.

The researchers also tested each of the drug combinations in a group of healthy mice, and found that the modified insulin and blood cell system reduced the risk of hypoglycemia compared to the other drug combinations.

Although, Hedrick and Linden target different cell types, innovations by both groups could encourage clinical tests of drugs designed to switch on a patient's immune cells by eradicating secondary lung malignancies.

LOS ANGELES, Calif. & BOSTON, Mass. — Investigators have demonstrated how cells of a human intestinal lining created outside an individual's body mirror living tissue when placed inside microengineered Intestine - Chips, opening the door to personalized testing of drug treatments.

Investigators from Cedars - Sinai and Emulate demonstrated how cells of a human intestinal lining created outside an individual's body mirror living tissue when placed inside Emulate's Intestine - Chips, opening the door to personalized testing of drug treatments.

Scientists are seeking the Food and Drug Administration's blessing for an unprecedented clinical trial — the first test of a drug to specifically target the process of human aging.

Differences between animal and human liver activity often result in under - reported human toxicities in preclinical animal testing of drug compounds.

In March, researchers, in collaboration with the pharmaceutical company Ultragenyx, completed the first part of a Phase III clinical trial in adults with XLH — the final test of a drug before federal approval.

Dr Dusko Ilic, leader of the team at King's College London, says: «Our new method can be used to grow much greater quantities of lab - grown human epidermal equivalents, and thus could be scaled up for commercial testing of drugs and cosmetics.

Tests of drug effects often rely on short - term surrogate indicators (say, change in cholesterol level), for instance, rather than eventual meaningful outcomes (say, heart attacks).

And in February, NIH and EPA announced a partnership to develop high - throughput toxicity testing of drugs and chemicals without animals.

But now that we can capture the most harmful cells and recreate the tumor itself for rapid response testing of drug combinations, in the very near future we can eradicate the entire tumor,» says Dr. Simeone.

In EXPEDITION3, the third test of the drug since it was developed in 2006, the compound failed once again to show significant benefit for people with mild forms of the disease.

In an earlier post by Altman & Altman, we discussed Zofran's pregnancy safety rating, which it purportedly received a rating of «Pregnancy Category B,» meaning that animal testing of this drug did not produce any concrete evidence that it would later become harmful in subjects who are pregnant.

Xarelto, a blood thinner linked to irreversible hemorrhaging and other serious medical problems, is now under investigation for problems that may have occurred during the FDA's initial testing of the drug.

He was also involved in the clinical testing of the drug, as was Max S. Topp, M.D., a former CRI postdoctoral fellow and now a professor at Würzburg University Hospital in Germany.

Testing of the drug in mouse models of Rett is now underway.

The company is currently in phase 2 testing of a drug that could one day treat diabetic macular edema.

«Because of this urgency, the testing of drugs like UCDA, which are already approved for other uses, is extremely valuable.

In September 2013 a report on the «crisis in cancer care» from the Institute of Medicine recommended offering drug companies a patent extension of six months on new drugs that have been tested in the elderly; a similar incentive has greatly increased the testing of drugs in children.

Published in the Journal of Clinical Investigation, the research team behind the findings hope that the new assay will enable the testing of drugs that aim to lower the production of the pathogenic mutant huntingtin protein that causes the disease, and could be useful in predicting or monitoring the progression of HD.

But fears that it would give alcoholics free rein to carry on drinking appear to have prevented the testing of the drug for this purpose.

«It is so important that we get blood pressure under control,» he says, that «there is strong justification» for a clinical trial to test some of these drugs.

A biomarker that could accurately identify those at greatest risk for cognitive decline could help clinicians better evaluate and treat patients, while also accelerating the testing of drugs to treat the disease.

For now, the testing of this drug will continue.

The government maintains highly stringent standards for the testing of drugs destined for the market.